Bifido and Protopic drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Bifido (bifidobacteria) and Protopic (tacrolimus). Common drug interactions include heart rate irregular among females and dyspnoea among males.

The phase IV clinical study analyzes what interactions people have when they take Bifido and Protopic. It is created by eHealthMe based on reports of 11 people who take the same drugs from the FDA, and is updated regularly.

What is Bifido?

Bifido has active ingredients of bifidobacteria. eHealthMe is studying from 5,030 Bifido users. Check the latest studies of Bifido.

What is Protopic?

Protopic has active ingredients of tacrolimus. It is often used in eczema. eHealthMe is studying from 5,403 Protopic users. Check the latest studies of Protopic.

On Jul, 17, 2026

11 people who take Bifido and Protopic together, and have interactions are studied.

What are the common drug interactions of Bifido and Protopic, by gender? *:

female:

Heart rate irregular
Pain
Aphasia (damage to the parts of the brain that control language)
Blood pressure decreased
Cardiac disorder
Diarrhoea
Dizziness
Erythema (redness of the skin)
Fatigue (feeling of tiredness)
Fluid overload (too much fluid in the blood)

male:

Dyspnoea (difficult or laboured respiration)
Therapeutic response decreased (less preventive response)

What are the common drug interactions of Bifido and Protopic, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

n/a

40-49:

Dermatitis atopic (inflammatory, chronically relapsing, non-contagious and pruritic skin disorder)
Pain
Peripheral swelling
Pruritus (severe itching of the skin)
Sleep disorder

50-59:

n/a

60+:

Dermatitis atopic (inflammatory, chronically relapsing, non-contagious and pruritic skin disorder)
Injection site pain
Pruritus (severe itching of the skin)
Rash

What are the existing conditions these people have? *

Dermatitis Atopic (inflammatory, chronically relapsing, non-contagious and pruritic skin disorder): 5 people, 45.45%
Systemic Lupus Erythematosus (an autoimmune disease, which means the body's immune system mistakenly, attacks healthy tissue): 4 people, 36.36%
Dermatomyositis (inflammation of the skin and underlying muscle tissue, typically occurring as an autoimmune condition or associated with internal cancer): 4 people, 36.36%
Psoriasis (immune-mediated disease that affects the skin): 3 people, 27.27%
Asthma: 2 people, 18.18%
Urticaria Chronic (long lasting rash of round, red welts on the skin that itch intensely): 1 person, 9.09%
Polymyositis (inflammatory muscle disease that causes weakness of the skeletal muscles): 1 person, 9.09%
Itching: 1 person, 9.09%
Idiopathic Urticaria (allergic reactions, presence of hives with unknown cause): 1 person, 9.09%
High Blood Pressure: 1 person, 9.09%

* Approximation only. Some reports may have incomplete information.

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