Bifidobacterium and Methylphenidate drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Bifidobacterium (bifidobacteria) and Methylphenidate (methylphenidate). Common drug interactions include hypertension among females and asthenia among males.

The phase IV clinical study analyzes what interactions people have when they take Bifidobacterium and Methylphenidate. It is created by eHealthMe based on reports of 13 people who take the same drugs from the FDA, and is updated regularly.

What is Bifidobacterium?

Bifidobacterium has active ingredients of bifidobacteria. eHealthMe is studying from 5,013 Bifidobacterium users. Check the latest studies of Bifidobacterium.

What is Methylphenidate?

Methylphenidate has active ingredients of methylphenidate. eHealthMe is studying from 8,216 Methylphenidate users. Check the latest studies of Methylphenidate.



On Jul, 11, 2026

13 people who take Bifidobacterium and Methylphenidate together, and have interactions are studied.

Bifidobacterium and Methylphenidate drug interactions.

What are the common drug interactions of Bifidobacterium and Methylphenidate, by gender? *:

female:

  1. Hypertension (high blood pressure)
  2. Injection site erythema (redness at injection site)
  3. Urticaria (rash of round, red welts on the skin that itch intensely)
  4. Decreased appetite
  5. Dysphonia (speech disorder attributable to a disorder of phonation)
  6. Headache (pain in head)
  7. Insomnia (sleeplessness)
  8. Palpitations (feelings or sensations that your heart is pounding or racing)
  9. Paraesthesia (sensation of tingling, tickling, prickling, pricking, or burning of a person's skin with no apparent long-term physical effect)
  10. Anxiety

male:

  1. Asthenia (weakness)
  2. Fatigue (feeling of tiredness)
  3. Malaise (a feeling of general discomfort or uneasiness)
  4. Middle insomnia (difficulty returning to sleep after awakening either in the middle of the night)
  5. Neuralgia (pain in one or more nerves)
  6. Pyrexia (fever)
  7. Sinusitis (inflammation of sinus)
  8. Skin ulcer
  9. Upper respiratory tract infection
  10. Vasculitis (inflammation of a blood vessel or blood vessels)

What are the common drug interactions of Bifidobacterium and Methylphenidate, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

  1. Asthma

10-19:

n/a

20-29:

n/a

30-39:

  1. Decreased appetite
  2. Dysphonia (speech disorder attributable to a disorder of phonation)
  3. Headache (pain in head)
  4. Hypertension (high blood pressure)
  5. Insomnia (sleeplessness)
  6. Palpitations (feelings or sensations that your heart is pounding or racing)
  7. Paraesthesia (sensation of tingling, tickling, prickling, pricking, or burning of a person's skin with no apparent long-term physical effect)

40-49:

n/a

50-59:

  1. Aphonia (inability to produce voice)
  2. Asthenia (weakness)
  3. Back disorder
  4. Fatigue (feeling of tiredness)
  5. Heart valve incompetence (heart's valves do not work correctly)
  6. Infection
  7. Infusion site bruising
  8. Insomnia (sleeplessness)
  9. Laryngitis (inflammation of the larynx)
  10. Malaise (a feeling of general discomfort or uneasiness)

60+:

  1. Fatigue (feeling of tiredness)
  2. Arthralgia (joint pain)
  3. Pain
  4. Pneumonia
  5. Pruritus (severe itching of the skin)
  6. Asthenia (weakness)
  7. Cough
  8. Decreased appetite
  9. Flank pain (a distressing sensation experienced around the lower back and the upper abdomen)
  10. Injection site erythema (redness at injection site)

What are the existing conditions these people have? *

  1. Narcolepsy (brain's inability to regulate sleep-wake cycles normally): 4 people, 30.77%
  2. Cataplexy (loss of muscle tone accompanied by full conscious awareness): 4 people, 30.77%
  3. Primary Immunodeficiency Syndrome: 3 people, 23.08%
  4. Constipation: 2 people, 15.38%
  5. Rheumatoid Arthritis (a chronic progressive disease causing inflammation in the joints): 1 person, 7.69%
  6. Interstitial Lung Disease: 1 person, 7.69%
  7. Immunodeficiency Common Variable: 1 person, 7.69%
  8. Idiopathic Pulmonary Fibrosis (chronic lung disease): 1 person, 7.69%
  9. Drowsiness: 1 person, 7.69%
  10. Asthma: 1 person, 7.69%

* Approximation only. Some reports may have incomplete information.

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Related studies:

Effectiveness of, side effects of, and alternative drugs to the 2 drugs:

Browse all drug interactions of Bifidobacterium and Methylphenidate:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Bifidobacterium:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all side effects of Methylphenidate:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Bifidobacterium and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Methylphenidate and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

How the study uses the data?

The study uses data from the FDA. It is based on bifidobacteria and methylphenidate (the active ingredients of Bifidobacterium and Methylphenidate, respectively), and Bifidobacterium and Methylphenidate (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

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