Biktarvy and Valacyclovir hydrochloride drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Biktarvy (bictegravir sodium; emtricitabine; tenofovir alafenamide fumarate) and Valacyclovir hydrochloride (valacyclovir hydrochloride). Common drug interactions include back pain among females and anxiety among males.

The phase IV clinical study analyzes what interactions people have when they take Biktarvy and Valacyclovir hydrochloride. It is created by eHealthMe based on reports of 60 people who take the same drugs from the FDA, and is updated regularly.

What is Biktarvy?

Biktarvy has active ingredients of bictegravir sodium; emtricitabine; tenofovir alafenamide fumarate. It is often used in hiv infection. eHealthMe is studying from 19,543 Biktarvy users. Check the latest studies of Biktarvy.

What is Valacyclovir hydrochloride?

Valacyclovir hydrochloride has active ingredients of valacyclovir hydrochloride. It is often used in herpes zoster. eHealthMe is studying from 12,929 Valacyclovir hydrochloride users. Check the latest studies of Valacyclovir hydrochloride.

On Jul, 26, 2026

60 people who take Biktarvy and Valacyclovir hydrochloride together, and have interactions are studied.

Biktarvy and Valacyclovir hydrochloride drug interactions.

What are the common drug interactions of Biktarvy and Valacyclovir Hydrochloride, by gender? *:

female:

Back pain
Blood creatinine increased
Bone loss
Bone pain
Decreased activity
Foot fracture
Fractured sacrum
Joint range of motion decreased (disease of joint movement)
Joint swelling
Nephropathy (damage to or disease of a kidney)

male:

Anxiety
Emotional distress
Renal failure (kidney dysfunction)
Gait disturbance
Hypertension (high blood pressure)
Insomnia (sleeplessness)
Renal impairment (severely reduced kidney function)
Arthralgia (joint pain)
Bone pain
Mobility decreased (ability to move is reduced)

What are the common drug interactions of Biktarvy and Valacyclovir Hydrochloride, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

Hospitalisation

30-39:

Drug resistance (reduction in effectiveness of a drug)
Anxiety
Chronic kidney disease
Depression
Emotional distress
Pain
Pollakiuria (abnormally frequent passage of relatively small quantities or urine)
Pulmonary embolism (blockage of the main artery of the lung)
Thrombosis (formation of a blood clot inside a blood vessel)

40-49:

Quality of life decreased
Bone disorder
Bone loss
Decreased activity
Drug ineffective
Fanconi syndrome acquired (self developed genetic disease of kidney damage due to defective transport system)
Femur fracture
Hypokalaemia (low potassium)
Immune system disorder
Impaired work ability

50-59:

Emotional distress
Pain
Anhedonia (inability to experience pleasure from activities usually found enjoyable)
Anxiety
Osteopenia (a condition where bone mineral density is lower than normal)
Osteoporosis (bones weak and more likely to break)
Blood creatinine increased
Chronic kidney disease
Renal failure (kidney dysfunction)
Anaemia (lack of blood)

60+:

Anhedonia (inability to experience pleasure from activities usually found enjoyable)
Anxiety
Bone pain
Osteoporosis (bones weak and more likely to break)
Tubulointerstitial nephritis (a form of nephritis affecting the interstitium of the kidneys surrounding the tubules)
Back pain
Balance disorder
Blood creatinine increased
Chronic kidney disease
Clavicle fracture

What are the existing conditions these people have? *

Pain: 6 people, 10.00%
Insomnia (sleeplessness): 6 people, 10.00%
Mycobacterium Avium Complex Infection: 4 people, 6.67%
Viral Infection: 3 people, 5.00%
Kaposi's Sarcoma (a tumour caused by human herpes virus): 3 people, 5.00%
Diarrhea: 3 people, 5.00%
Depression: 3 people, 5.00%
Bacterial Infection: 3 people, 5.00%

* Approximation only. Some reports may have incomplete information.

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