Biotin and Apresoline drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Biotin (biotin) and Apresoline (hydralazine hydrochloride). Common drug interactions include fatigue among females and dehydration among males.

The phase IV clinical study analyzes what interactions people have when they take Biotin and Apresoline. It is created by eHealthMe based on reports of 15 people who take the same drugs from the FDA, and is updated regularly.

What is Biotin?

Biotin has active ingredients of biotin. It is often used in hair loss. eHealthMe is studying from 35,393 Biotin users. Check the latest studies of Biotin.

What is Apresoline?

Apresoline has active ingredients of hydralazine hydrochloride. It is often used in high blood pressure. eHealthMe is studying from 2,475 Apresoline users. Check the latest studies of Apresoline.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.

On Aug, 16, 2026

15 people who take Biotin and Apresoline together, and have interactions are studied.

Biotin and Apresoline drug interactions.

What are the common drug interactions of Biotin and Apresoline, by gender? *:

female:

Fatigue (feeling of tiredness)
Abdominal distension
Abdominal pain
Back pain
Device dislocation
Dysmenorrhoea (painful menstruation)
Dyspnoea (difficult or laboured respiration)
Lymphocyte count decreased
Menorrhagia (an abnormally heavy bleeding and prolonged menstrual period at regular intervals)
Migraine (headache)

male:

Dehydration (dryness resulting from the removal of water)
Diabetic ketoacidosis (diabetic ketoacidosis (dka) is high concentrations of ketone bodies)
Subdural haematoma (blood collects between the skull and the surface of the brain)
Urinary incontinence (inability to control the flow of urine and involuntary urination)
Vomiting
Electrocardiogram qt prolonged
Blood alcohol increased
Ecchymosis (a discoloration of the skin resulting from bleeding underneath)
Fall
Limb discomfort (discomfort in leg)

What are the common drug interactions of Biotin and Apresoline, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

n/a

40-49:

Abdominal distension
Abdominal pain
Device dislocation
Dysmenorrhoea (painful menstruation)
Fatigue (feeling of tiredness)
Lymphocyte count decreased
Menorrhagia (an abnormally heavy bleeding and prolonged menstrual period at regular intervals)
Migraine (headache)
Uterine haemorrhage (uterine bleeding)
Haemangioma of skin (noncancerous, abnormally dense collections of dilated small blood vessels that may occur in the skin or internal organs)

50-59:

Dehydration (dryness resulting from the removal of water)
Diabetic ketoacidosis (diabetic ketoacidosis (dka) is high concentrations of ketone bodies)
Electrocardiogram qt prolonged

60+:

Back pain
Dyspnoea (difficult or laboured respiration)
Injury
Limb injury
Pain in jaw
Skin wound
Blood alcohol increased
Blood glucose increased
Cholecystitis (infection of gallbladder)
Cognitive disorder (mental health disorders affects learning, memory, perception, and problem solving)

What are the existing conditions these people have? *

Pain: 6 people, 40.00%
Depression: 4 people, 26.67%
Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 4 people, 26.67%
Hypertonic Bladder (bladder-storage function that causes a sudden urge to urinate): 3 people, 20.00%
Multiple Sclerosis (a nervous system disease that affects your brain and spinal cord. it damages the myelin sheath): 3 people, 20.00%
High Blood Cholesterol: 3 people, 20.00%
Migraine Without Aura (headache without neurological problems): 3 people, 20.00%
Biotin Deficiency: 2 people, 13.33%
Chest Pain: 2 people, 13.33%
Chronic Obstructive Pulmonary Disease (a progressive disease that makes it hard to breathe): 2 people, 13.33%

* Approximation only. Some reports may have incomplete information.

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