Bisacodyl and Atarax drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Bisacodyl (bisacodyl) and Atarax (hydroxyzine hydrochloride). Common drug interactions include tricuspid valve incompetence among females and rash maculo-papular among males.

The phase IV clinical study analyzes what interactions people have when they take Bisacodyl and Atarax. It is created by eHealthMe based on reports of 80 people who take the same drugs from the FDA, and is updated regularly.

What is Bisacodyl?

Bisacodyl has active ingredients of bisacodyl. It is often used in constipation. eHealthMe is studying from 18,852 Bisacodyl users. Check the latest studies of Bisacodyl.

What is Atarax?

Atarax has active ingredients of hydroxyzine hydrochloride. It is often used in stress and anxiety. eHealthMe is studying from 23,553 Atarax users. Check the latest studies of Atarax.



On Jul, 11, 2026

80 people who take Bisacodyl and Atarax together, and have interactions are studied.

Bisacodyl and Atarax drug interactions.

What are the common drug interactions of Bisacodyl and Atarax, by gender? *:

female:

  1. Tricuspid valve incompetence (inefficient heart valve)
  2. Type 2 diabetes mellitus
  3. Irritability
  4. Nausea (feeling of having an urge to vomit)
  5. Abdominal distension
  6. Abdominal mass (localized enlargement or swelling in the human abdomen)
  7. Abscess intestinal (collections of pus-intestinal)
  8. Agranulocytosis (a deficiency of granulocytes in the blood, causing increased vulnerability to infection)
  9. Aortic arteriosclerosis (hardening of the aortic arteries)
  10. Aortic valve incompetence

male:

  1. Rash maculo-papular (red area on the skin that is covered with small confluent bumps)
  2. Eosinophilia (eosinophil count in the peripheral blood exceeds)
  3. Hypertension (high blood pressure)
  4. Perirectal abscess
  5. Pyrexia (fever)
  6. Renal failure (kidney dysfunction)
  7. Staphylococcal sepsis (blood infection by an infection with staphylococcus bacteria)
  8. Aortic valve disease
  9. Arthritis (form of joint disorder that involves inflammation of one or more joints)
  10. Mitral valve disease (disease of mitral valve of heart)

What are the common drug interactions of Bisacodyl and Atarax, by age (0-1 to 60+)? *:

0-1:

  1. Alanine aminotransferase increased
  2. Anaemia (lack of blood)
  3. Aspartate aminotransferase increased
  4. Atelectasis (partial or complete collapse of the lung)
  5. Blood alkaline phosphatase increased
  6. Blood lactate dehydrogenase increased
  7. Carbon dioxide decreased
  8. Cellulitis (infection under the skin)
  9. Cough
  10. Diarrhoea

2-9:

n/a

10-19:

n/a

20-29:

  1. Pulmonary embolism (blockage of the main artery of the lung)

30-39:

  1. Anaemia (lack of blood)
  2. Chest pain
  3. Hyperkalaemia (damage to or disease of the kidney)
  4. Hypertension (high blood pressure)
  5. Cellulitis (infection under the skin)
  6. Cellulitis staphylococcal (a type of bacteria originated skin soft tissue infection)
  7. Deformity (disfigurement)
  8. Dyspnoea (difficult or laboured respiration)
  9. Emotional distress
  10. Fatigue (feeling of tiredness)

40-49:

  1. Anaphylactic shock (severe and rapid and sometimes fatal hypersensitivity reaction to a substance)
  2. Bone pain
  3. Burning sensation
  4. Dizziness
  5. Feeling cold
  6. Mobility decreased (ability to move is reduced)
  7. Multiple allergies (allergy to multiple agents)
  8. Nephrogenic systemic fibrosis (involves fibrosis of skin, joints, eyes due to kidney disease)
  9. Osteitis (a general term for inflammation of bone)
  10. Urinary retention (the inability to completely or partially empty the bladder)

50-59:

  1. Back pain
  2. Bursitis (inflammation of a bursa, typically one in the knee, elbow, or shoulder)
  3. Compulsive shopping
  4. Depression
  5. Drug abuse
  6. Drug dependence
  7. Drug withdrawal syndrome (interfere with normal social, occupational, or other functioning. are not due to another medical condition, drug use, or discontinuation)
  8. Dry skin
  9. Gastric ulcer (stomach ulcer)
  10. Impulse-control disorder

60+:

  1. Rash maculo-papular (red area on the skin that is covered with small confluent bumps)
  2. Cellulitis (infection under the skin)
  3. Pleural effusion (water on the lungs)
  4. Skin lesion
  5. Vomiting
  6. Chronic obstructive pulmonary disease (a progressive disease that makes it hard to breathe)
  7. Dermatitis exfoliative (widespread scaling of the skin, often with itching (pruritus), skin redness (erythroderma), and hair loss)
  8. Gastrointestinal haemorrhage (bleeding gastrointestinal tract)
  9. Haematuria (presence of blood in urine)
  10. Hypoxia (low oxygen in tissues)

What are the existing conditions these people have? *

  1. Pain: 20 people, 25.00%
  2. High Blood Pressure: 14 people, 17.50%
  3. Itching: 8 people, 10.00%
  4. Insomnia (sleeplessness): 8 people, 10.00%
  5. Nausea (feeling of having an urge to vomit): 7 people, 8.75%
  6. Muscle Spasms (muscle contraction): 7 people, 8.75%
  7. Sleep Disorder: 6 people, 7.50%
  8. Depression: 6 people, 7.50%
  9. Neuralgia (pain in one or more nerves): 6 people, 7.50%
  10. Multiple Myeloma (cancer of the plasma cells): 6 people, 7.50%

* Approximation only. Some reports may have incomplete information.

Do you take Bisacodyl and Atarax?

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Related studies:

Effectiveness of, side effects of, and alternative drugs to the 2 drugs:

Browse all drug interactions of Bisacodyl and Atarax:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Bisacodyl:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all side effects of Atarax:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Bisacodyl and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Atarax and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Related publications that referenced our studies


How the study uses the data?

The study uses data from the FDA. It is based on bisacodyl and hydroxyzine hydrochloride (the active ingredients of Bisacodyl and Atarax, respectively), and Bisacodyl and Atarax (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.



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