Bisacodyl and Isoptin drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Bisacodyl (bisacodyl) and Isoptin (verapamil hydrochloride). Common drug interactions include renal failure among females and agitation among males.

The phase IV clinical study analyzes what interactions people have when they take Bisacodyl and Isoptin. It is created by eHealthMe based on reports of 21 people who take the same drugs from the FDA, and is updated regularly.

What is Bisacodyl?

Bisacodyl has active ingredients of bisacodyl. It is often used in constipation. eHealthMe is studying from 18,852 Bisacodyl users. Check the latest studies of Bisacodyl.

What is Isoptin?

Isoptin has active ingredients of verapamil hydrochloride. It is often used in high blood pressure. eHealthMe is studying from 5,539 Isoptin users. Check the latest studies of Isoptin.

On Jul, 17, 2026

21 people who take Bisacodyl and Isoptin together, and have interactions are studied.

Bisacodyl and Isoptin drug interactions.

What are the common drug interactions of Bisacodyl and Isoptin, by gender? *:

female:

Renal failure (kidney dysfunction)
Toxic epidermal necrolysis (a rare, life-threatening skin condition that is usually caused by a reaction to drugs causes wide spread skin destruction)
Brain injury
Leukocytosis (increased white blood cells)
Pneumonia
Rash
Stevens-johnson syndrome (an immune-complex-mediated hypersensitivity disorder. it ranges from mild skin and mucous membrane lesions to a severe)
Blister (small pocket of fluid within the upper layers of the skin caused by forceful rubbing (friction), burning, freezing, chemical exposure)
Pruritus (severe itching of the skin)
Blood creatinine increased

male:

Agitation (state of anxiety or nervous excitement)
Agoraphobia (extreme or irrational fear of crowded spaces or enclosed public places)
Atrioventricular block complete (heart block complete)
Blood cholesterol increased
Bradycardia (abnormally slow heart action)
Bundle branch block (disruption in the normal flow of electrical pulses that drive the heart beat)
Bundle branch block right (absence of transmission of electric impulses from the atrioventricular (av) bundle of his to the right ventricle)
Cardiomegaly (increased size of heart than normal)
Cataract (clouding of the lens inside the eye)
Chest pain

What are the common drug interactions of Bisacodyl and Isoptin, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

n/a

40-49:

n/a

50-59:

Brain injury
Renal failure (kidney dysfunction)
Toxic epidermal necrolysis (a rare, life-threatening skin condition that is usually caused by a reaction to drugs causes wide spread skin destruction)
Leukocytosis (increased white blood cells)
Pneumonia
Stevens-johnson syndrome (an immune-complex-mediated hypersensitivity disorder. it ranges from mild skin and mucous membrane lesions to a severe)
Pruritus (severe itching of the skin)
Rash
Blister (small pocket of fluid within the upper layers of the skin caused by forceful rubbing (friction), burning, freezing, chemical exposure)
Blood creatinine increased

60+:

Anaemia (lack of blood)
Deep vein thrombosis (blood clot in a major vein that usually develops in the legs and/or pelvis)
Rash
Renal failure (kidney dysfunction)
Respiratory failure (inadequate gas exchange by the respiratory system)
Septic shock (shock due to blood infection)
Speech disorder
Toxic epidermal necrolysis (a rare, life-threatening skin condition that is usually caused by a reaction to drugs causes wide spread skin destruction)
Ventricular fibrillation (abnormally irregular heart rhythm)
Agitation (state of anxiety or nervous excitement)

What are the existing conditions these people have? *

Acute Kidney Failure: 16 people, 76.19%
Arrhythmias (irregular heartbeat): 16 people, 76.19%
Systemic Sclerosis (Scleroderma) (an autoimmune or connective tissue disease. it is characterized by thickening of the skin): 15 people, 71.43%
Sleep Disorder: 15 people, 71.43%
Pain: 15 people, 71.43%
Anaemia (lack of blood): 15 people, 71.43%
Nausea (feeling of having an urge to vomit): 15 people, 71.43%
Infection: 15 people, 71.43%
Fever: 15 people, 71.43%
Heart Disease: 15 people, 71.43%

* Approximation only. Some reports may have incomplete information.

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