Bisacodyl and Solu-cortef drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Bisacodyl (bisacodyl) and Solu-cortef (hydrocortisone sodium succinate). Common drug interactions include oropharyngeal pain among females and hypoxia among males.

The phase IV clinical study analyzes what interactions people have when they take Bisacodyl and Solu-cortef. It is created by eHealthMe based on reports of 30 people who take the same drugs from the FDA, and is updated regularly.

What is Bisacodyl?

Bisacodyl has active ingredients of bisacodyl. It is often used in constipation. eHealthMe is studying from 18,852 Bisacodyl users. Check the latest studies of Bisacodyl.

What is Solu-cortef?

Solu-cortef has active ingredients of hydrocortisone sodium succinate. eHealthMe is studying from 7,983 Solu-cortef users. Check the latest studies of Solu-cortef.



On Jul, 19, 2026

30 people who take Bisacodyl and Solu-cortef together, and have interactions are studied.

Bisacodyl and Solu-cortef drug interactions.

What are the common drug interactions of Bisacodyl and Solu-Cortef, by gender? *:

female:

  1. Oropharyngeal pain
  2. Thrombocytopenia (decrease of platelets in blood)
  3. Urinary tract infection
  4. Gastrooesophageal reflux disease (stomach contents (food or liquid) leak backwards from the stomach into the oesophagus)
  5. Occipital neuralgia (a condition characterized by chronic pain in the upper neck)
  6. Vitamin d decreased
  7. Acidosis (build-up of carbon dioxide in the blood)
  8. Anaemia (lack of blood)
  9. Arthralgia (joint pain)
  10. Asthenia (weakness)

male:

  1. Hypoxia (low oxygen in tissues)
  2. Anxiety
  3. Bone density decreased
  4. Bone disorder
  5. Bone pain
  6. Breakthrough pain
  7. Bursitis infective (the bursa can become infected, this is called infected bursitis)
  8. Cellulitis (infection under the skin)
  9. Cholecystitis infective (infection of gallbladder capable to infect other organs)
  10. Decreased appetite

What are the common drug interactions of Bisacodyl and Solu-Cortef, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

  1. Fatigue (feeling of tiredness)
  2. Diarrhoea
  3. Fall
  4. Infusion related reaction
  5. Oropharyngeal pain
  6. Pain
  7. Back pain
  8. Blood alkaline phosphatase increased
  9. Blood creatinine decreased
  10. Blood phosphorus increased

20-29:

n/a

30-39:

n/a

40-49:

  1. Brain neoplasm (tumour of brain)
  2. Cervical spinal stenosis (narrowing of the spinal canal in the neck)
  3. Depression
  4. Diabetes mellitus (diabetes, caused by a deficiency of the pancreatic hormone insulin)
  5. Dysphagia (a condition in which swallowing is difficult or painful)
  6. Eczema (patches of skin become rough and inflamed, with itching and bleeding blisters)
  7. Ill-defined disorder
  8. Mastication disorder (disease of chewing food)
  9. Mobility decreased (ability to move is reduced)
  10. Multiple sclerosis relapse (reoccurrence of a nervous system disease that affects your brain and spinal cord. it damages the myelin sheath)

50-59:

  1. Pyrexia (fever)
  2. Renal failure (kidney dysfunction)
  3. Restlessness (not able to rest)
  4. Sepsis (a severe blood infection that can lead to organ failure and death)
  5. Subdural haematoma (blood collects between the skull and the surface of the brain)
  6. Weight decreased
  7. Wound
  8. Bursitis infective (the bursa can become infected, this is called infected bursitis)
  9. Cellulitis (infection under the skin)
  10. Asthenia (weakness)

60+:

  1. Anaemia (lack of blood)
  2. Dyspnoea (difficult or laboured respiration)
  3. Biliary sepsis
  4. Bone density decreased
  5. Bone disorder
  6. Bone pain
  7. Breakthrough pain
  8. Cholecystitis infective (infection of gallbladder capable to infect other organs)
  9. Decreased appetite
  10. Dizziness

What are the existing conditions these people have? *

  1. Prostate Cancer: 4 people, 13.33%
  2. Insomnia (sleeplessness): 4 people, 13.33%
  3. Multiple Sclerosis (a nervous system disease that affects your brain and spinal cord. it damages the myelin sheath): 4 people, 13.33%
  4. Depression: 3 people, 10.00%
  5. High Blood Pressure: 3 people, 10.00%
  6. Nausea (feeling of having an urge to vomit): 3 people, 10.00%
  7. Nausea And Vomiting: 3 people, 10.00%
  8. Pain: 3 people, 10.00%
  9. Immunodeficiency Common Variable: 3 people, 10.00%
  10. Sepsis (a severe blood infection that can lead to organ failure and death): 3 people, 10.00%

* Approximation only. Some reports may have incomplete information.

Do you take Bisacodyl and Solu-cortef?

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Related studies:

Effectiveness of, side effects of, and alternative drugs to the 2 drugs:

Browse all drug interactions of Bisacodyl and Solu-cortef:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Bisacodyl:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all side effects of Solu-cortef:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Bisacodyl and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Solu-cortef and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

How the study uses the data?

The study uses data from the FDA. It is based on bisacodyl and hydrocortisone sodium succinate (the active ingredients of Bisacodyl and Solu-cortef, respectively), and Bisacodyl and Solu-cortef (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

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