Boniva and Azithromycin drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Boniva (ibandronate sodium) and Azithromycin (azithromycin). Common drug interactions include weight decreased among females and pain among males.

The phase IV clinical study analyzes what interactions people have when they take Boniva and Azithromycin. It is created by eHealthMe based on reports of 69 people who take the same drugs from the FDA, and is updated regularly.

What is Boniva?

Boniva has active ingredients of ibandronate sodium. It is often used in osteoporosis. eHealthMe is studying from 27,340 Boniva users. Check the latest studies of Boniva.

What is Azithromycin?

Azithromycin has active ingredients of azithromycin. It is often used in sinusitis. eHealthMe is studying from 40,716 Azithromycin users. Check the latest studies of Azithromycin.



On Jul, 14, 2026

69 people who take Boniva and Azithromycin together, and have interactions are studied.

Boniva and Azithromycin drug interactions.

What are the common drug interactions of Boniva and Azithromycin, by gender? *:

female:

  1. Weight decreased
  2. Dehydration (dryness resulting from the removal of water)
  3. Anaemia (lack of blood)
  4. Injury
  5. Diarrhoea
  6. Dyspnoea (difficult or laboured respiration)
  7. Nausea (feeling of having an urge to vomit)
  8. Arthritis (form of joint disorder that involves inflammation of one or more joints)
  9. Chronic obstructive pulmonary disease (a progressive disease that makes it hard to breathe)
  10. Constipation

male:

  1. Pain
  2. Anxiety
  3. Hypercholesterolaemia (high levels of cholesterol in the blood)
  4. Hypothyroidism (abnormally low activity of the thyroid gland, resulting in retardation of growth and mental development)
  5. Nervous system disorder (a general class of medical conditions affecting the nervous system)
  6. Osteoarthritis (a joint disease caused by cartilage loss in a joint)
  7. Amnesia (deficit in memory caused by brain damage, disease, or psychological trauma)
  8. Anaemia (lack of blood)
  9. Arthralgia (joint pain)
  10. Arthritis (form of joint disorder that involves inflammation of one or more joints)

What are the common drug interactions of Boniva and Azithromycin, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

  1. Dyspepsia (indigestion)
  2. Gastritis (inflammation of stomach)
  3. Haematuria (presence of blood in urine)
  4. Mass
  5. Pancreas infection
  6. Pancreatitis acute (sudden inflammation of pancreas)
  7. Pancreatitis necrotising (inflammation of the pancreas cause death of tissue in pancreas)
  8. Pleural effusion (water on the lungs)
  9. Renal cyst (kidney cyst)
  10. Splenic vein occlusion (blockage of splenic vein)

30-39:

n/a

40-49:

  1. Anaemia (lack of blood)
  2. Anxiety
  3. Arthralgia (joint pain)
  4. Back pain
  5. Bone disorder
  6. Chronic sinusitis (long lasting inflammation of the paranasal sinuses)
  7. Decreased interest
  8. Disability
  9. Diverticulum (out pouching of a hollow (or a fluid-filled) structure in the body)
  10. Dry eye (lack of adequate tears)

50-59:

  1. Dyspepsia (indigestion)
  2. Dyspnoea (difficult or laboured respiration)
  3. Fall
  4. Hypertension (high blood pressure)
  5. Hypotension (abnormally low blood pressure)
  6. Injury
  7. Mitral valve incompetence (inefficient heart valve)
  8. Palpitations (feelings or sensations that your heart is pounding or racing)
  9. Rotator cuff syndrome (a spectrum of conditions affecting the rotator cuff tendons of the shoulder)
  10. Stress fracture (fracture of a bone caused by repeated (rather than sudden) mechanical stress)

60+:

  1. Cardiac failure congestive
  2. Hypotension (abnormally low blood pressure)
  3. Respiratory failure (inadequate gas exchange by the respiratory system)
  4. Diarrhoea
  5. Nausea (feeling of having an urge to vomit)
  6. Arthritis (form of joint disorder that involves inflammation of one or more joints)
  7. Colitis ischaemic (due to infection of intestine impaired blood supply to colon)
  8. Pain
  9. Sinus tachycardia (a heart rhythm with elevated rate of impulses originating from the sinoatrial node)
  10. Urosepsis (secondary infection that occurs when a urinary tract infection spreads to the bloodstream)

What are the existing conditions these people have? *

  1. Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 9 people, 13.04%
  2. High Blood Cholesterol: 8 people, 11.59%
  3. Arrhythmias (irregular heartbeat): 8 people, 11.59%
  4. Pain: 7 people, 10.14%
  5. High Blood Pressure: 7 people, 10.14%
  6. Infection: 5 people, 7.25%
  7. Osteopenia (a condition where bone mineral density is lower than normal): 4 people, 5.80%

* Approximation only. Some reports may have incomplete information.

Do you take Boniva and Azithromycin?

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Related studies:

Effectiveness of, side effects of, and alternative drugs to the 2 drugs:

Browse all drug interactions of Boniva and Azithromycin:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Boniva:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all side effects of Azithromycin:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Boniva and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Azithromycin and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

How the study uses the data?

The study uses data from the FDA. It is based on ibandronate sodium and azithromycin (the active ingredients of Boniva and Azithromycin, respectively), and Boniva and Azithromycin (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

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