Boniva and Tobi drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Boniva (ibandronate sodium) and Tobi (tobramycin). Common drug interactions include dysphonia among females and productive cough among males.

The phase IV clinical study analyzes what interactions people have when they take Boniva and Tobi. It is created by eHealthMe based on reports of 13 people who take the same drugs from the FDA, and is updated regularly.

What is Boniva?

Boniva has active ingredients of ibandronate sodium. It is often used in osteoporosis. eHealthMe is studying from 27,340 Boniva users. Check the latest studies of Boniva.

What is Tobi?

Tobi has active ingredients of tobramycin. eHealthMe is studying from 10,011 Tobi users. Check the latest studies of Tobi.

On Jul, 19, 2026

13 people who take Boniva and Tobi together, and have interactions are studied.

What are the common drug interactions of Boniva and Tobi, by gender? *:

female:

Dysphonia (speech disorder attributable to a disorder of phonation)
Pancreatitis acute (sudden inflammation of pancreas)
Amnesia (deficit in memory caused by brain damage, disease, or psychological trauma)
Fatigue (feeling of tiredness)
Insomnia (sleeplessness)
Abdominal pain upper
Anaemia (lack of blood)
Cerebrovascular accident (sudden death of some brain cells due to lack of oxygen when the blood flow to the brain is impaired by blockage or rupture)
Confusional state
Dyspnoea (difficult or laboured respiration)

male:

Productive cough
Bronchiectasis (abnormal widening of the bronchi or their branches, causing a risk of infection)
Pyrexia (fever)
Bronchitis (inflammation of the mucous membrane in the bronchial tubes)
Chronic obstructive pulmonary disease (a progressive disease that makes it hard to breathe)
Death
Gastrointestinal disorder (functional problems of gastrointestinal tract)
Liver disorder (liver diseases)
Lymphoma (cancer that begins in immune system cells)
Myopia (difficult to see objects that are far away)

What are the common drug interactions of Boniva and Tobi, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

Confusional state
Abdominal pain upper
Amnesia (deficit in memory caused by brain damage, disease, or psychological trauma)
Anaemia (lack of blood)
Aphasia (damage to the parts of the brain that control language)
Cerebrovascular accident (sudden death of some brain cells due to lack of oxygen when the blood flow to the brain is impaired by blockage or rupture)
Dizziness
Dyspnoea (difficult or laboured respiration)
Fatigue (feeling of tiredness)
Gastric ulcer (stomach ulcer)

40-49:

n/a

50-59:

Death
Blood creatine phosphokinase increased
Cerumen impaction
Colonic polyp (extra part of colon tissue grow in intestine)
Depression
Diverticulum (out pouching of a hollow (or a fluid-filled) structure in the body)
Ear infection
Eye disorder
Fatigue (feeling of tiredness)
Femur fracture

60+:

Dysphonia (speech disorder attributable to a disorder of phonation)
Pancreatitis acute (sudden inflammation of pancreas)
Chronic obstructive pulmonary disease (a progressive disease that makes it hard to breathe)
Gastric ulcer haemorrhage (bleeding ulcer of stomach)
Gastrointestinal disorder (functional problems of gastrointestinal tract)
Insomnia (sleeplessness)
Liver disorder (liver diseases)
Lymphoma (cancer that begins in immune system cells)
Nausea (feeling of having an urge to vomit)
Pneumonia pseudomonal (pseudomonas pneumonia is an infection caused by the microbe known as pseudomonas aeruginosa)

What are the existing conditions these people have? *

Cystic Fibrosis (disease of the secretary glands): 5 people, 38.46%
Pancreatic Insufficiency: 3 people, 23.08%
Pain: 3 people, 23.08%
Lung Disorder (lung disease): 3 people, 23.08%
Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 3 people, 23.08%
Senile Osteoporosis (weak bones with ageing): 1 person, 7.69%
Infective Pulmonary Exacerbation Of Cystic Fibrosis (severe infective lung disease with production of abnormally thick mucus): 1 person, 7.69%
Chronic Obstructive Pulmonary Disease (a progressive disease that makes it hard to breathe): 1 person, 7.69%
Bronchiectasis (abnormal widening of the bronchi or their branches, causing a risk of infection): 1 person, 7.69%
Ankylosing Spondylitis (type of arthritis affecting the spine): 1 person, 7.69%

* Approximation only. Some reports may have incomplete information.

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