Bortezomib and Alphagan drug interactions - a phase IV clinical study of FDA data
Summary:
Drug interactions are reported among people who take Bortezomib (bortezomib) and Alphagan (brimonidine tartrate). Common drug interactions include peripheral sensorimotor neuropathy among females and cardio-respiratory arrest among males.
The phase IV clinical study analyzes what interactions people have when they take Bortezomib and Alphagan. It is created by eHealthMe based on reports of 11 people who take the same drugs from the FDA, and is updated regularly.
What is Bortezomib?
Bortezomib has active ingredients of bortezomib. eHealthMe is studying from 30,912 Bortezomib users. Check the latest studies of Bortezomib.
What is Alphagan?
Alphagan has active ingredients of brimonidine tartrate. It is often used in glaucoma. eHealthMe is studying from 9,981 Alphagan users. Check the latest studies of Alphagan.
11 people who take Bortezomib and Alphagan together, and have interactions are studied.

What are the common drug interactions of Bortezomib and Alphagan, by gender? *:
female:
- Peripheral sensorimotor neuropathy (damage to one or more of your peripheral nerves)
- Embolism (obstruction of an artery, typically by a clot of blood or an air bubble)
- Neutropenia (an abnormally low number of neutrophils)
- Thrombocytopenia (decrease of platelets in blood)
male:
- Cardio-respiratory arrest (sudden dysfunction of heart and lungs)
- Hypoxic-ischaemic encephalopathy (a condition that occurs when the entire brain is deprived of an adequate oxygen supply, but the deprivation isn't total)
- Exposed bone in jaw
- Gilbert's syndrome (liver condition in which the liver doesn't properly process a substance called bilirubin)
- Lung disorder (lung disease)
- Neuropathy peripheral (surface nerve damage)
- Plasma cell myeloma (cancer that begins in plasma cells)
- Pneumonitis (inflammation of the walls of the alveoli in the lungs)
- Psoriatic arthropathy (inflammation of the skin and joints with kin condition which typically causes patches (plaques) of red, scaly skin to develop)
- Thrombocytopenia (decrease of platelets in blood)
What are the common drug interactions of Bortezomib and Alphagan, by age (0-1 to 60+)? *:
0-1:
n/a
2-9:
n/a
10-19:
n/a
20-29:
n/a
30-39:
n/a
40-49:
n/a
50-59:
- Cardio-respiratory arrest (sudden dysfunction of heart and lungs)
- Hypoxic-ischaemic encephalopathy (a condition that occurs when the entire brain is deprived of an adequate oxygen supply, but the deprivation isn't total)
- Pyrexia (fever)
- Pulmonary embolism (blockage of the main artery of the lung)
- Neutropenia (an abnormally low number of neutrophils)
- Thrombocytopenia (decrease of platelets in blood)
60+:
- Peripheral sensorimotor neuropathy (damage to one or more of your peripheral nerves)
- Embolism (obstruction of an artery, typically by a clot of blood or an air bubble)
- Lung disorder (lung disease)
- Neuropathy peripheral (surface nerve damage)
- Plasma cell myeloma (cancer that begins in plasma cells)
- Pneumonitis (inflammation of the walls of the alveoli in the lungs)
- Psoriatic arthropathy (inflammation of the skin and joints with kin condition which typically causes patches (plaques) of red, scaly skin to develop)
- Thrombocytopenia (decrease of platelets in blood)
- Thyroid neoplasm (tumour of thyroid)
- Tooth disorder (tooth disease)
What are the existing conditions these people have? *
- Multiple Myeloma (cancer of the plasma cells): 11 people, 100.00%
- Constipation: 3 people, 27.27%
- Deep Venous Thrombosis (blood clot in a major vein that usually develops in the legs and/or pelvis): 3 people, 27.27%
- Discomfort: 3 people, 27.27%
- Uveitis (inflammation of the uvea): 3 people, 27.27%
- Hyperglycemia (high blood sugar): 3 people, 27.27%
- High Blood Pressure: 2 people, 18.18%
- Wheezing (a high-pitched whistling sound made while you breath): 1 person, 9.09%
- Atrial Fibrillation/flutter (atrial fibrillation and flutter are abnormal heart rhythms in which the atria, or upper chambers of the heart, are out of sync with the ventricles): 1 person, 9.09%
- Cardiac Failure: 1 person, 9.09%
* Approximation only. Some reports may have incomplete information.
Do you take Bortezomib and Alphagan?
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- Predict drug outcomes for up to one year with AI
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Related studies:
Effectiveness of, side effects of, and alternative drugs to the 2 drugs:
- Bortezomib (30,912 reports)
- Alphagan (9,981 reports)
Browse all drug interactions of Bortezomib and Alphagan:
a b c d e f g h i j k l m n o p q r s t u v w x y zSub-studies by gender and age:
Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Browse all side effects of Bortezomib:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all side effects of Alphagan:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Bortezomib and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Alphagan and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zHow the study uses the data?
The study uses data from the FDA. It is based on bortezomib and brimonidine tartrate (the active ingredients of Bortezomib and Alphagan, respectively), and Bortezomib and Alphagan (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.
How to use the study?
DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.
Who is eHealthMe?
With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).
WARNING, DISCLAIMER, USE FOR PUBLICATION
WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.
DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.
If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.
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