Bosentan and Montelukast sodium drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Bosentan (bosentan) and Montelukast sodium (montelukast sodium). Common drug interactions include chest pain among females and death among males.

The phase IV clinical study analyzes what interactions people have when they take Bosentan and Montelukast sodium. It is created by eHealthMe based on reports of 18 people who take the same drugs from the FDA, and is updated regularly.

What is Bosentan?

Bosentan has active ingredients of bosentan. eHealthMe is studying from 10,925 Bosentan users. Check the latest studies of Bosentan.

What is Montelukast sodium?

Montelukast sodium has active ingredients of montelukast sodium. It is often used in asthma. eHealthMe is studying from 26,093 Montelukast sodium users. Check the latest studies of Montelukast sodium.

On Jul, 12, 2026

18 people who take Bosentan and Montelukast sodium together, and have interactions are studied.

Bosentan and Montelukast sodium drug interactions.

What are the common drug interactions of Bosentan and Montelukast Sodium, by gender? *:

female:

Chest pain
Cough
Injection site infection
Pain in extremity
Pruritus (severe itching of the skin)
Weight increased
Breast cancer
Constipation
Device failure
Drug hypersensitivity

male:

Death
Diarrhoea
Renal impairment (severely reduced kidney function)
Bowel movement irregularity
Constipation

What are the common drug interactions of Bosentan and Montelukast Sodium, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

n/a

40-49:

Injection site infection
Breast cancer
Device failure
Headache (pain in head)
Injection site discolouration
Injection site erythema (redness at injection site)
Injection site induration
Injection site pain
Injection site pruritus (severe itching at injection site)
Injection site rash

50-59:

Diarrhoea
Malaise (a feeling of general discomfort or uneasiness)
Weight decreased
Arthralgia (joint pain)
Atrial flutter (an abnormal heart rhythm that occurs in the atria of the heart)
Dyspnoea (difficult or laboured respiration)
Fluid retention (an abnormal accumulation of fluid in the blood)
Heart rate increased
Hot flush (sudden feelings of heat)
Limb discomfort (discomfort in leg)

60+:

Chest pain
Constipation
Tachycardia (a heart rate that exceeds the range of 100 beats/min)
Weight increased
Wheezing (a high-pitched whistling sound made while you breath)
Abdominal pain
Anger
Anxiety
Asthenia (weakness)
Back pain

What are the existing conditions these people have? *

Primary Pulmonary Hypertension (primary high blood pressure that affects the arteries in the lungs and the right side of your heart): 16 people, 88.89%
Iron Deficiency Anaemia: 4 people, 22.22%
High Blood Pressure: 3 people, 16.67%
Hyperuricaemia (level of uric acid in the blood that is abnormally high): 2 people, 11.11%
Haemorrhage (bleeding): 2 people, 11.11%
Essential Thrombocythaemia (chronic blood cancer): 2 people, 11.11%
Folate Deficiency (lack of folic acid): 2 people, 11.11%
Magnesium Deficiency (lack of magnesium): 2 people, 11.11%
Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 2 people, 11.11%
Hypokalemia (low potassium): 2 people, 11.11%

* Approximation only. Some reports may have incomplete information.

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