Bosulif and Alprazolam drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Bosulif (bosutinib) and Alprazolam (alprazolam). Common drug interactions include arthralgia among females and diarrhoea among males.

The phase IV clinical study analyzes what interactions people have when they take Bosulif and Alprazolam. It is created by eHealthMe based on reports of 64 people who take the same drugs from the FDA, and is updated regularly.

What is Bosulif?

Bosulif has active ingredients of bosutinib. eHealthMe is studying from 9,401 Bosulif users. Check the latest studies of Bosulif.

What is Alprazolam?

Alprazolam has active ingredients of alprazolam. It is often used in stress and anxiety. eHealthMe is studying from 134,864 Alprazolam users. Check the latest studies of Alprazolam.

On Jul, 14, 2026

64 people who take Bosulif and Alprazolam together, and have interactions are studied.

Bosulif and Alprazolam drug interactions.

What are the common drug interactions of Bosulif and Alprazolam, by gender? *:

female:

Arthralgia (joint pain)
Cholestasis (a condition where bile cannot flow from the liver to the duodenum)
Diverticulum (out pouching of a hollow (or a fluid-filled) structure in the body)
Drug hypersensitivity
Electrocardiogram qt prolonged
Fluid overload (too much fluid in the blood)
Haemoptysis (blood-stained sputum from the bronchi, larynx, trachea, or lungs)
Iron deficiency
Onycholysis (detachment of the nail from the nail bed)
Pulmonary oedema (fluid accumulation in the lungs)

male:

Diarrhoea
Depressed mood
Lip swelling
Nasopharyngitis (inflammation of the nasopharynx)
Peripheral swelling
Pulmonary fibrosis (formation or development of excess fibrous connective tissue (fibrosis) in the lungs)
Abnormal faeces (abnormal stool)
Affect lability (emotional incontinence)
Amnesia (deficit in memory caused by brain damage, disease, or psychological trauma)
Arthropathy

What are the common drug interactions of Bosulif and Alprazolam, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

Pneumonia
Abdominal pain
Anaemia (lack of blood)
Cholestasis (a condition where bile cannot flow from the liver to the duodenum)
Constipation
Diarrhoea
Diverticulum (out pouching of a hollow (or a fluid-filled) structure in the body)
Electrocardiogram qt prolonged
Haemoptysis (blood-stained sputum from the bronchi, larynx, trachea, or lungs)
Iron deficiency

30-39:

Abdominal pain
Arthralgia (joint pain)
Dyspnoea (difficult or laboured respiration)
Hypersensitivity
Nausea (feeling of having an urge to vomit)
Platelet count increased
Rash
Urticaria (rash of round, red welts on the skin that itch intensely)
Vomiting

40-49:

Diarrhoea
Nausea (feeling of having an urge to vomit)
Abdominal pain upper
Drug ineffective
Dyspepsia (indigestion)
Fatigue (feeling of tiredness)
Platelet count decreased
Pyrexia (fever)
Retching (strong involuntary effort to vomit)
Sepsis (a severe blood infection that can lead to organ failure and death)

50-59:

Abdominal discomfort
Bone pain
Depression
Fatigue (feeling of tiredness)
Infectious mononucleosis (infection usually caused by the epstein-barr virus)
Oropharyngeal pain
Pain of skin
Skin disorder (skin disease)
Hospitalisation
Abdominal pain

60+:

Diarrhoea
Fatigue (feeling of tiredness)
Arthralgia (joint pain)
Cough
Disturbance in attention
Haematochezia (passage of stools containing blood)
Impaired driving ability
Insomnia (sleeplessness)
Joint swelling
Limb injury

What are the existing conditions these people have? *

Chronic Myeloid Leukaemia (long lasting type of cancer that starts in the blood-forming cells of the bone marrow and invades the blood): 52 people, 81.25%
High Blood Pressure: 10 people, 15.62%
Pain: 9 people, 14.06%
Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 9 people, 14.06%
Sleep Disorder: 8 people, 12.50%
Hypothyroidism (abnormally low activity of the thyroid gland, resulting in retardation of growth and mental development): 8 people, 12.50%
Pain In Extremity: 6 people, 9.38%
Osteitis (a general term for inflammation of bone): 6 people, 9.38%
Diabetes: 6 people, 9.38%
Atrial Fibrillation/flutter (atrial fibrillation and flutter are abnormal heart rhythms in which the atria, or upper chambers of the heart, are out of sync with the ventricles): 6 people, 9.38%

* Approximation only. Some reports may have incomplete information.

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