Brintellix and Centrum drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Brintellix (vortioxetine hydrobromide) and Centrum (ascorbic acid; biotin; cyanocobalamin; dexpanthenol; ergocalciferol; folic acid; niacinamide; pyridoxine hydrochloride; riboflavin phosphate sodium; thiamine hydrochloride; vitamin a; vitamin e). Common drug interactions include nausea among females.

The phase IV clinical study analyzes what interactions people have when they take Brintellix and Centrum. It is created by eHealthMe based on reports of 13 people who take the same drugs from the FDA, and is updated regularly.

What is Brintellix?

Brintellix has active ingredients of vortioxetine hydrobromide. It is often used in depression. eHealthMe is studying from 6,748 Brintellix users. Check the latest studies of Brintellix.

What is Centrum?

Centrum has active ingredients of ascorbic acid; biotin; cyanocobalamin; dexpanthenol; ergocalciferol; folic acid; niacinamide; pyridoxine hydrochloride; riboflavin phosphate sodium; thiamine hydrochloride; vitamin a; vitamin e. It is often used in vitamin supplementation. eHealthMe is studying from 34,686 Centrum users. Check the latest studies of Centrum.

On Jul, 10, 2026

13 people who take Brintellix and Centrum together, and have interactions are studied.

Brintellix and Centrum drug interactions.

What are the common drug interactions of Brintellix and Centrum, by gender? *:

female:

Nausea (feeling of having an urge to vomit)
Drug ineffective
Anxiety
Aphasia (damage to the parts of the brain that control language)
Hyperparathyroidism secondary (an abnormally high concentration of parathyroid hormone in the blood, resulting in weakening of the bones through loss of calcium-secondary)
Hypertonic bladder (bladder-storage function that causes a sudden urge to urinate)
Irritable bowel syndrome
Movement disorder (neurological syndromes where they may be excess of movement or a paucity of movement that is not connected to weakness)
Nasopharyngitis (inflammation of the nasopharynx)
Oedema (fluid collection in tissue)

male:

n/a

What are the common drug interactions of Brintellix and Centrum, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

n/a

40-49:

n/a

50-59:

Arthralgia (joint pain)
Blood alkaline phosphatase decreased
Blood calcium decreased
Blood calcium increased
Blood chloride decreased
Blood cholesterol increased
Blood parathyroid hormone decreased
Blood triglycerides increased
Fall
Glycosylated haemoglobin increased

60+:

Drug ineffective
Tinnitus (a ringing in the ears)
Weight increased
Nausea (feeling of having an urge to vomit)
Nightmare (unpleasant dream)
Crying

What are the existing conditions these people have? *

Sleep Disorder: 4 people, 30.77%
Diabetes: 4 people, 30.77%
Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 4 people, 30.77%
High Blood Cholesterol: 4 people, 30.77%
Thyroid Diseases: 3 people, 23.08%
Joint Pain: 3 people, 23.08%
Back Pain: 3 people, 23.08%
Bladder Disorder: 3 people, 23.08%
Blood Pressure Abnormal: 3 people, 23.08%
Cataplexy (loss of muscle tone accompanied by full conscious awareness): 3 people, 23.08%

* Approximation only. Some reports may have incomplete information.

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