Brintellix and Trileptal drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Brintellix (vortioxetine hydrobromide) and Trileptal (oxcarbazepine). Common drug interactions include myositis among females and headache among males.

The phase IV clinical study analyzes what interactions people have when they take Brintellix and Trileptal. It is created by eHealthMe based on reports of 15 people who take the same drugs from the FDA, and is updated regularly.

What is Brintellix?

Brintellix has active ingredients of vortioxetine hydrobromide. It is often used in depression. eHealthMe is studying from 6,748 Brintellix users. Check the latest studies of Brintellix.

What is Trileptal?

Trileptal has active ingredients of oxcarbazepine. It is often used in bipolar disorder. eHealthMe is studying from 23,558 Trileptal users. Check the latest studies of Trileptal.

On Aug, 02, 2026

15 people who take Brintellix and Trileptal together, and have interactions are studied.

Brintellix and Trileptal drug interactions.

What are the common drug interactions of Brintellix and Trileptal, by gender? *:

female:

Myositis (inflammation of the muscles)
Obsessive rumination (thinking and worry or rumination is an inability to gain control over recurrent, distressing thoughts, images)
Papilloma viral infection
Psychotic disorder
Salivary hypersecretion (excess saliva secretion)
Trismus (reduced opening of the jaws)
Agitation (state of anxiety or nervous excitement)
Alopecia (absence of hair from areas of the body)
Back injury
Claustrophobia (fear of having no escape and being closed in small spaces)

male:

Headache (pain in head)
Precancerous mucosal lesion
Allergy to chemicals
Bronchitis chronic (inflammation of the mucous membrane in the bronchial tubes- chronic)
Chronic obstructive pulmonary disease (a progressive disease that makes it hard to breathe)
Pneumonia aspiration (bronchopneumonia that develops due to the entrance of foreign materials into the bronchial tree)
Sleep apnoea syndrome (a sleep-related disorder in which the effort to breathe is diminished or absent)

What are the common drug interactions of Brintellix and Trileptal, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

Nausea (feeling of having an urge to vomit)
Panic attack
Vomiting

30-39:

Endometriosis (appearance of endometrial tissue outside the uterus and causing pelvic pain)
Myositis (inflammation of the muscles)
Deafness
Ear infection
Hypertension (high blood pressure)
Memory impairment
Pneumonia aspiration (bronchopneumonia that develops due to the entrance of foreign materials into the bronchial tree)
Sleep apnoea syndrome (a sleep-related disorder in which the effort to breathe is diminished or absent)
Weight increased
Incontinence (lack of moderation or self-control)

40-49:

n/a

50-59:

n/a

60+:

n/a

What are the existing conditions these people have? *

Cataplexy (loss of muscle tone accompanied by full conscious awareness): 9 people, 60.00%
Narcolepsy (brain's inability to regulate sleep-wake cycles normally): 9 people, 60.00%
Major Depression (a mood state that goes well beyond temporarily feeling sad or blue. it is a serious medical illness that affects one's thoughts, feelings): 3 people, 20.00%
Scoliosis (a medical condition in which a person's spine is curved from side to side): 2 people, 13.33%
Fibromyalgia (a long-term condition which causes pain all over the body): 2 people, 13.33%
Hypersensitivity: 2 people, 13.33%
Gastritis (inflammation of stomach): 1 person, 6.67%
Drowsiness: 1 person, 6.67%
Dyskinesia (abnormality or impairment of voluntary movement): 1 person, 6.67%
Dyspnea (difficult or laboured breathing): 1 person, 6.67%

* Approximation only. Some reports may have incomplete information.

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