Brintellix and Zopiclone drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Brintellix (vortioxetine hydrobromide) and Zopiclone (eszopiclone). Common drug interactions include general physical health deterioration among females and dyskinesia among males.

The phase IV clinical study analyzes what interactions people have when they take Brintellix and Zopiclone. It is created by eHealthMe based on reports of 85 people who take the same drugs from the FDA, and is updated regularly.

What is Brintellix?

Brintellix has active ingredients of vortioxetine hydrobromide. It is often used in depression. eHealthMe is studying from 6,748 Brintellix users. Check the latest studies of Brintellix.

What is Zopiclone?

Zopiclone has active ingredients of eszopiclone. It is often used in insomnia. eHealthMe is studying from 54,330 Zopiclone users. Check the latest studies of Zopiclone.

On Jul, 11, 2026

85 people who take Brintellix and Zopiclone together, and have interactions are studied.

Brintellix and Zopiclone drug interactions.

What are the common drug interactions of Brintellix and Zopiclone, by gender? *:

female:

General physical health deterioration (weak health status)
Hyponatraemia (abnormally low level of sodium in the blood; associated with dehydration)
Coma (state of unconsciousness lasting more than six hours)
Overdose
Pancreatitis (inflammation of pancreas)
Bradypnoea (an abnormally slow respiratory rate)
Poisoning deliberate
Suicidal ideation
Fall
Somnambulism (sleep walking)

male:

Dyskinesia (abnormality or impairment of voluntary movement)
Confusional state
Hyponatraemia (abnormally low level of sodium in the blood; associated with dehydration)
Fatigue (feeling of tiredness)
Headache (pain in head)
Loss of consciousness
Respiratory acidosis (respiratory failure or ventilatory failure, causes the ph of blood and other bodily fluids to decrease)
Suicidal ideation
Tachycardia (a heart rate that exceeds the range of 100 beats/min)
Aggression

What are the common drug interactions of Brintellix and Zopiclone, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

Coma (state of unconsciousness lasting more than six hours)
Bradypnoea (an abnormally slow respiratory rate)
Overdose
Poisoning deliberate
Dyskinesia (abnormality or impairment of voluntary movement)
Serotonin syndrome (occurs when two drugs that affect the body's level of serotonin are taken together at the same time)
Tinnitus (a ringing in the ears)

30-39:

Somnambulism (sleep walking)
Asthenia (weakness)
Brain injury
Completed suicide (act of taking one's own life)
Extrapyramidal disorder (involuntary muscle spasms in the face and neck)
Hypoglycaemia (deficiency of glucose in the bloodstream)
Overdose
Pneumonia aspiration (bronchopneumonia that develops due to the entrance of foreign materials into the bronchial tree)
Restless legs syndrome (a powerful urge to move your legs)
Suicidal ideation

40-49:

Confusional state
Depressed level of consciousness
Cognitive disorder (mental health disorders affects learning, memory, perception, and problem solving)
Dizziness
Muscular weakness (muscle weakness)
Nausea (feeling of having an urge to vomit)
Paraesthesia (sensation of tingling, tickling, prickling, pricking, or burning of a person's skin with no apparent long-term physical effect)
Dysgeusia (disorder of the sense of taste)
Photopsia (presence of perceived flashes of light)
Diarrhoea

50-59:

Hyponatraemia (abnormally low level of sodium in the blood; associated with dehydration)
Loss of consciousness
Respiratory acidosis (respiratory failure or ventilatory failure, causes the ph of blood and other bodily fluids to decrease)
Suicidal ideation
Tachycardia (a heart rate that exceeds the range of 100 beats/min)
Diarrhoea
Dry eye (lack of adequate tears)
Fatigue (feeling of tiredness)
Headache (pain in head)
Malaise (a feeling of general discomfort or uneasiness)

60+:

General physical health deterioration (weak health status)
Hyponatraemia (abnormally low level of sodium in the blood; associated with dehydration)
Suicide attempt
Analgesic drug level increased
Psychomotor skills impaired
Sedation
Bladder spasm
Cognitive disorder (mental health disorders affects learning, memory, perception, and problem solving)
Dermatitis allergic (inflammation of the skin due allergic reaction)
Dizziness

What are the existing conditions these people have? *

Stress And Anxiety: 13 people, 15.29%
Sleep Disorder: 8 people, 9.41%
High Blood Cholesterol: 6 people, 7.06%
Poisoning Deliberate: 5 people, 5.88%

* Approximation only. Some reports may have incomplete information.

Do you take Brintellix and Zopiclone?

- Personalize this study to your gender, age, symptoms and drugs
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously