Briviact and Divalproex sodium drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Briviact (brivaracetam) and Divalproex sodium (divalproex sodium). Common drug interactions include seizure among females and seizure among males.

The phase IV clinical study analyzes what interactions people have when they take Briviact and Divalproex sodium. It is created by eHealthMe based on reports of 28 people who take the same drugs from the FDA, and is updated regularly.

What is Briviact?

Briviact has active ingredients of brivaracetam. It is often used in epilepsy. eHealthMe is studying from 3,433 Briviact users. Check the latest studies of Briviact.

What is Divalproex sodium?

Divalproex sodium has active ingredients of divalproex sodium. It is often used in epilepsy. eHealthMe is studying from 9,483 Divalproex sodium users. Check the latest studies of Divalproex sodium.



On Jul, 25, 2026

28 people who take Briviact and Divalproex sodium together, and have interactions are studied.

Briviact and Divalproex sodium drug interactions.

What are the common drug interactions of Briviact and Divalproex Sodium, by gender? *:

female:

  1. Seizure (abnormal excessive or synchronous neuronal activity in the brain)
  2. Diarrhoea
  3. Balance disorder
  4. Breast cancer
  5. Drug ineffective
  6. Dysphagia (a condition in which swallowing is difficult or painful)
  7. Memory impairment
  8. Overdose
  9. Sedation
  10. Somnolence (a state of near-sleep, a strong desire for sleep)

male:

  1. Seizure (abnormal excessive or synchronous neuronal activity in the brain)
  2. Affective disorder (mental disorder)
  3. Discomfort
  4. Drug hypersensitivity
  5. Dry skin
  6. Fatigue (feeling of tiredness)
  7. Gastrointestinal pain
  8. Hospitalisation
  9. Hyponatraemia (abnormally low level of sodium in the blood; associated with dehydration)
  10. Irritability

What are the common drug interactions of Briviact and Divalproex Sodium, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

  1. Seizure (abnormal excessive or synchronous neuronal activity in the brain)

10-19:

  1. Diarrhoea
  2. Seizure (abnormal excessive or synchronous neuronal activity in the brain)
  3. Vomiting
  4. Infusion site pain
  5. Vomiting projectile
  6. Abdominal pain
  7. Discomfort
  8. Dry skin
  9. Gastrointestinal pain
  10. Hospitalisation

20-29:

  1. Seizure (abnormal excessive or synchronous neuronal activity in the brain)
  2. Affective disorder (mental disorder)
  3. Disturbance in attention
  4. Drug ineffective
  5. Nausea (feeling of having an urge to vomit)
  6. Sedation
  7. Vomiting
  8. Seizure cluster (small group of seizure)

30-39:

n/a

40-49:

  1. Mental disorder (a psychological term for a mental or behavioural pattern or anomaly that causes distress or disability)
  2. Seizure (abnormal excessive or synchronous neuronal activity in the brain)
  3. Drug hypersensitivity
  4. Hyponatraemia (abnormally low level of sodium in the blood; associated with dehydration)
  5. Partial seizures (seizures which affect only a part of the brain at onset)

50-59:

  1. Death
  2. Abnormal behaviour
  3. Hallucinations, mixed (sensations that appear real but are created by your mind -mixed)
  4. Myoclonus (a brief, involuntary twitching of a muscle or a group of muscles)
  5. Seizure (abnormal excessive or synchronous neuronal activity in the brain)
  6. Suicidal ideation

60+:

  1. Balance disorder
  2. Breast cancer
  3. Chronic kidney disease
  4. Drug ineffective
  5. Dysphagia (a condition in which swallowing is difficult or painful)
  6. Memory impairment
  7. Overdose
  8. Sedation
  9. Seizure (abnormal excessive or synchronous neuronal activity in the brain)
  10. Somnolence (a state of near-sleep, a strong desire for sleep)

What are the existing conditions these people have? *

  1. Seizures (abnormal excessive or synchronous neuronal activity in the brain): 15 people, 53.57%
  2. Wheezing (a high-pitched whistling sound made while you breath): 3 people, 10.71%
  3. Stress And Anxiety: 3 people, 10.71%
  4. Lennox-Gastaut Syndrome (epilepsy characterized by frequent seizures and different seizure types): 3 people, 10.71%
  5. Temporal Lobe Epilepsy (a term that refers to a condition where seizures are generated in the portion of the brain called the temporal lobe): 2 people, 7.14%
  6. Rashes (redness): 2 people, 7.14%
  7. Irritability: 2 people, 7.14%
  8. Hypersensitivity: 2 people, 7.14%
  9. Anger: 2 people, 7.14%

* Approximation only. Some reports may have incomplete information.

Do you take Briviact and Divalproex sodium?

- Personalize this study to your gender, age, symptoms and drugs
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously



Related studies:

Effectiveness of, side effects of, and alternative drugs to the 2 drugs:

Browse all drug interactions of Briviact and Divalproex sodium:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Briviact:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all side effects of Divalproex sodium:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Briviact and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Divalproex sodium and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

How the study uses the data?

The study uses data from the FDA. It is based on brivaracetam and divalproex sodium (the active ingredients of Briviact and Divalproex sodium, respectively), and Briviact and Divalproex sodium (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.



Recent studies on eHealthMe: