Budesonide and Prograf drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Budesonide (budesonide) and Prograf (tacrolimus). Common drug interactions include cellulitis among females and fatigue among males.

The phase IV clinical study analyzes what interactions people have when they take Budesonide and Prograf. It is created by eHealthMe based on reports of 87 people who take the same drugs from the FDA, and is updated regularly.

What is Budesonide?

Budesonide has active ingredients of budesonide. It is often used in asthma. eHealthMe is studying from 42,933 Budesonide users. Check the latest studies of Budesonide.

What is Prograf?

Prograf has active ingredients of tacrolimus. It is often used in kidney transplant. eHealthMe is studying from 42,230 Prograf users. Check the latest studies of Prograf.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.

On Aug, 27, 2026

87 people who take Budesonide and Prograf together, and have interactions are studied.

Budesonide and Prograf drug interactions.

What are the common drug interactions of Budesonide and Prograf, by gender? *:

female:

Cellulitis (infection under the skin)
Colitis (inflammation of colon)
Conjunctival disorder (conjunctival disease)
Conjunctival oedema (conjunctival swelling)
Contusion (a type of hematoma of tissue in which capillaries)
Cushingoid (obesity and weakening of the muscles)
Cytomegalovirus infection
Cytomegalovirus viraemia (cytomegalo virus in blood stream)
Defaecation urgency (a sudden compelling urge to defecate)
Dental caries

male:

Fatigue (feeling of tiredness)
Diarrhoea
Weight increased
Abdominal pain
Blood pressure decreased
Brain oedema (excess accumulation of fluid in the intracellular or extracellular spaces of the brain)
Bruxism (habitual grinding of the teeth, typically during sleep)
Depressed level of consciousness
Disseminated intravascular coagulation (systemic activation of blood coagulation)
Dyskinesia (abnormality or impairment of voluntary movement)

What are the common drug interactions of Budesonide and Prograf, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

Intra-abdominal haemorrhage (intra-abdominal bleeding)

10-19:

Bronchopulmonary aspergillosis (lung disorder caused by aspergillus fungi)
Bacteroides bacteraemia
Graft versus host disease (the donated bone marrow or stem cells view the recipient's body as foreign, and the donated cells/bone marrow attack the body)
Thrombotic microangiopathy (a pathology that results in thrombosis in capillaries and arterioles, due to an endothelial injury)
Abdominal pain
Adrenal insufficiency (a condition in which the adrenal glands do not produce adequate amounts of steroids)
Bacteraemia (presence of bacteria in the blood)
Bk virus infection
Cytomegalovirus hepatitis (virus infection of liver)
Cytomegalovirus infection

20-29:

Blood pressure decreased
Brain oedema (excess accumulation of fluid in the intracellular or extracellular spaces of the brain)
Bruxism (habitual grinding of the teeth, typically during sleep)
Depressed level of consciousness
Disseminated intravascular coagulation (systemic activation of blood coagulation)
Dyskinesia (abnormality or impairment of voluntary movement)
Ecchymosis (a discoloration of the skin resulting from bleeding underneath)
Fatigue (feeling of tiredness)
Kidney transplant rejection
Mydriasis (a dilation of the pupil)

30-39:

Thrombotic microangiopathy (a pathology that results in thrombosis in capillaries and arterioles, due to an endothelial injury)
Abdominal pain
Constipation
Hepatic enzyme increased
Death
Diarrhoea
Hypersensitivity
Lethargy (tiredness)
Oesophageal candidiasis (fungal infection of oesophagus)
Overdose

40-49:

Activated partial thromboplastin time prolonged
Cardiac arrest
Catatonia (unresponsive to external stimuli)
Catheter bacteraemia (bacterial infection in blood due to catheter)
Constipation
Depression
Haematocrit decreased
Haemoglobin decreased
Headache (pain in head)
International normalised ratio increased

50-59:

Hyperglycaemia (high blood sugar)
Hyperkalaemia (damage to or disease of the kidney)
Hypoaldosteronism (decreased levels of the hormone aldosterone)
Hypothyroidism (abnormally low activity of the thyroid gland, resulting in retardation of growth and mental development)
Immunosuppressant drug level increased
Injection site bruising
Insomnia (sleeplessness)
Intestinal polyp (small growths in the bowel with the potential for further growth)
Lymphadenopathy (disease or enlargement of lymph nodes)
Lymphopenia (an abnormally low level of lymphocytes in the blood)

60+:

Renal failure (kidney dysfunction)
Cough
Haemorrhage intracranial (bleeding within the skull)
Abdominal discomfort
Abdominal pain
Acute graft versus host disease in intestine (acute complication in intestine following an allogeneic tissue/blood transplant)
Ascites (accumulation of fluid in the abdominal cavity)
Atrial fibrillation (fibrillation of the muscles of the atria of the heart)
Basophil percentage decreased
Blood alkaline phosphatase increased

What are the existing conditions these people have? *

Graft Versus Host Disease (the donated bone marrow or stem cells view the recipient's body as foreign, and the donated cells/bone marrow attack the body): 12 people, 13.79%
Cystic Fibrosis (disease of the secretary glands): 9 people, 10.34%
Diarrhea: 8 people, 9.20%
Nausea (feeling of having an urge to vomit): 7 people, 8.05%
High Blood Pressure: 7 people, 8.05%
Diabetes: 7 people, 8.05%
Acute Myeloid Leukaemia (acute cancer in which the bone marrow makes abnormal myeloblasts): 5 people, 5.75%

* Approximation only. Some reports may have incomplete information.

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