Bumetanide and Eprex drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Bumetanide (bumetanide) and Eprex (epoetin alfa). Common drug interactions include immunosuppressant drug level increased among females and drug ineffective among males.

The phase IV clinical study analyzes what interactions people have when they take Bumetanide and Eprex. It is created by eHealthMe based on reports of 34 people who take the same drugs from the FDA, and is updated regularly.

What is Bumetanide?

Bumetanide has active ingredients of bumetanide. It is often used in fluid retention. eHealthMe is studying from 20,532 Bumetanide users. Check the latest studies of Bumetanide.

What is Eprex?

Eprex has active ingredients of epoetin alfa. eHealthMe is studying from 5,554 Eprex users. Check the latest studies of Eprex.



On Jul, 13, 2026

34 people who take Bumetanide and Eprex together, and have interactions are studied.

Bumetanide and Eprex drug interactions.

What are the common drug interactions of Bumetanide and Eprex, by gender? *:

female:

  1. Immunosuppressant drug level increased
  2. Renal impairment (severely reduced kidney function)
  3. Atrial fibrillation (fibrillation of the muscles of the atria of the heart)
  4. Cardiac failure congestive
  5. Pericardial effusion (fluid around the heart)
  6. Coma (state of unconsciousness lasting more than six hours)
  7. Conjunctival haemorrhage (bleeding underneath the conjunctiva)
  8. Drug administration error
  9. Neutropenia (an abnormally low number of neutrophils)
  10. Pancytopenia (medical condition in which there is a reduction in the number of red and white blood cells, as well as platelets)

male:

  1. Drug ineffective
  2. Red cell aplasia (a type of anaemia affecting the precursors to red blood cells)
  3. Intra-abdominal haemangioma (intra-abdominal non-cancerous tumour)
  4. Renal failure chronic (long lasting kidney dysfunction)
  5. Abdominal distension
  6. Blood creatinine increased
  7. Complement factor c3 decreased
  8. Cough
  9. Decreased appetite
  10. Diarrhoea

What are the common drug interactions of Bumetanide and Eprex, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

  1. Abdominal distension
  2. Anaemia (lack of blood)
  3. Blood creatinine increased
  4. Blood potassium increased
  5. Complement factor c3 decreased
  6. Cough
  7. Decreased appetite
  8. Diarrhoea
  9. Drug ineffective
  10. Eyelid oedema (eyelids are swollen and contain excessive fluid)

30-39:

n/a

40-49:

  1. Coma (state of unconsciousness lasting more than six hours)
  2. Mouth haemorrhage (bleeding from mouth)
  3. Neutropenia (an abnormally low number of neutrophils)
  4. Peritonitis (inflammation of the peritoneum, the thin tissue that lines the inner wall of the abdomen and covers most of the abdominal organs)
  5. Petechiae (a small red or purple spot caused by bleeding into the skin)
  6. Thrombocytopaenic purpura (a bleeding disorder in which the immune system destroys platelets)
  7. Thrombocytopenic purpura (a bleeding disorder in which the immune system destroys platelets)
  8. White blood cell count decreased

50-59:

n/a

60+:

  1. Drug ineffective
  2. Immunosuppressant drug level increased
  3. General physical health deterioration (weak health status)
  4. Haemangioma (noncancerous, abnormally dense collections of dilated small blood vessels that may occur in the skin or internal organs)
  5. Intra-abdominal haemangioma (intra-abdominal non-cancerous tumour)
  6. Pericardial effusion (fluid around the heart)
  7. Renal failure chronic (long lasting kidney dysfunction)
  8. Activated partial thromboplastin time shortened
  9. Acute hepatic failure
  10. Acute respiratory distress syndrome

What are the existing conditions these people have? *

  1. Lower Respiratory Tract Infection: 7 people, 20.59%
  2. Right Ventricular Failure (right half of the heart fails to work): 2 people, 5.88%
  3. Non-Hodgkin's Lymphoma (malignant (cancer) cells form in the lymph system): 2 people, 5.88%
  4. Chronic Renal Failure (kidney failure): 2 people, 5.88%

* Approximation only. Some reports may have incomplete information.

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Related studies:

Effectiveness of, side effects of, and alternative drugs to the 2 drugs:

Browse all drug interactions of Bumetanide and Eprex:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Bumetanide:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all side effects of Eprex:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Bumetanide and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Eprex and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

How the study uses the data?

The study uses data from the FDA. It is based on bumetanide and epoetin alfa (the active ingredients of Bumetanide and Eprex, respectively), and Bumetanide and Eprex (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

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