Bumetanide and Nexavar drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Bumetanide (bumetanide) and Nexavar (sorafenib tosylate). Common drug interactions include nausea among females and nausea among males.

The phase IV clinical study analyzes what interactions people have when they take Bumetanide and Nexavar. It is created by eHealthMe based on reports of 24 people who take the same drugs from the FDA, and is updated regularly.

What is Bumetanide?

Bumetanide has active ingredients of bumetanide. It is often used in fluid retention. eHealthMe is studying from 20,532 Bumetanide users. Check the latest studies of Bumetanide.

What is Nexavar?

Nexavar has active ingredients of sorafenib tosylate. It is often used in hepatocellular carcinoma. eHealthMe is studying from 23,250 Nexavar users. Check the latest studies of Nexavar.

On Jul, 12, 2026

24 people who take Bumetanide and Nexavar together, and have interactions are studied.

Bumetanide and Nexavar drug interactions.

What are the common drug interactions of Bumetanide and Nexavar, by gender? *:

female:

Nausea (feeling of having an urge to vomit)
Chest pain
Deep vein thrombosis (blood clot in a major vein that usually develops in the legs and/or pelvis)
Convulsion (muscles contract and relax rapidly and repeatedly, resulting in an uncontrolled shaking of the body)
Abdominal pain
Acne (skin problems that cause pimples)
Alanine aminotransferase increased
Aspartate aminotransferase increased
Dysuria (painful or difficult urination)
Hepatorenal syndrome (renal failure in patients with advanced chronic liver disease)

male:

Nausea (feeling of having an urge to vomit)
Alanine aminotransferase increased
Hypokalaemia (low potassium)
Drug hypersensitivity
Dyspnoea (difficult or laboured respiration)
Ejection fraction decreased (systolic heart failure)
Erythema (redness of the skin)
Fatigue (feeling of tiredness)
Left ventricular failure (left ventricle fails to contract forcefully)
Skin toxicity (skin damage due to toxin/poison)

What are the common drug interactions of Bumetanide and Nexavar, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

Blood pressure fluctuation
Hypokalaemia (low potassium)
Nausea (feeling of having an urge to vomit)
Pain
Thrombosis (formation of a blood clot inside a blood vessel)
Hepatic enzyme increased
Hospitalisation

30-39:

Nausea (feeling of having an urge to vomit)
Abdominal pain
Acne (skin problems that cause pimples)
Alanine aminotransferase increased
Aspartate aminotransferase increased
Dysuria (painful or difficult urination)
Hepatorenal syndrome (renal failure in patients with advanced chronic liver disease)
Pyrexia (fever)
Vomiting
Vulval abscess

40-49:

Drug ineffective
Scrotal infection (infection in scrotum area)
Scrotal swelling
Balance disorder
Unresponsive to stimuli

50-59:

Alanine aminotransferase increased
Aspartate aminotransferase increased
Multi-organ failure (multisystem organ failure)
Nausea (feeling of having an urge to vomit)
Vomiting
Chest pain
Deep vein thrombosis (blood clot in a major vein that usually develops in the legs and/or pelvis)
Cholelithiasis (the presence or formation of gallstones in the gallbladder or bile ducts)
Hospitalisation
Renal disorder (kidney disease)

60+:

Diarrhoea
Drug hypersensitivity
Gait disturbance
Insomnia (sleeplessness)
Irritability
Limb discomfort (discomfort in leg)
Muscular weakness (muscle weakness)
Oedema (fluid collection in tissue)
Pain
Convulsion (muscles contract and relax rapidly and repeatedly, resulting in an uncontrolled shaking of the body)

What are the existing conditions these people have? *

Hepatic Neoplasm Malignant (liver cancer): 5 people, 20.83%
Nausea (feeling of having an urge to vomit): 4 people, 16.67%
High Blood Pressure: 4 people, 16.67%
Cough: 4 people, 16.67%
Pain: 3 people, 12.50%
Oedema Peripheral (superficial swelling): 3 people, 12.50%
Hypothyroidism (abnormally low activity of the thyroid gland, resulting in retardation of growth and mental development): 3 people, 12.50%
Hepatitis B: 3 people, 12.50%
Abdominal Distension: 3 people, 12.50%
Type 2 Diabetes: 2 people, 8.33%

* Approximation only. Some reports may have incomplete information.

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