Bumex and Adalat drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Bumex (bumetanide) and Adalat (nifedipine). Common drug interactions include blood pressure decreased among females and pain among males.

The phase IV clinical study analyzes what interactions people have when they take Bumex and Adalat. It is created by eHealthMe based on reports of 32 people who take the same drugs from the FDA, and is updated regularly.

What is Bumex?

Bumex has active ingredients of bumetanide. It is often used in swelling. eHealthMe is studying from 9,210 Bumex users. Check the latest studies of Bumex.

What is Adalat?

Adalat has active ingredients of nifedipine. It is often used in high blood pressure. eHealthMe is studying from 20,940 Adalat users. Check the latest studies of Adalat.



On Jul, 06, 2026

32 people who take Bumex and Adalat together, and have interactions are studied.

Bumex and Adalat drug interactions.

What are the common drug interactions of Bumex and Adalat, by gender? *:

female:

  1. Blood pressure decreased
  2. Body temperature decreased
  3. Bronchospasm (spasm of bronchial smooth muscle producing narrowing of the bronchi)
  4. Bundle branch block right (absence of transmission of electric impulses from the atrioventricular (av) bundle of his to the right ventricle)
  5. Cardiovascular disorder (heart diseases)
  6. Congestive (dilated) cardiomyopathy (weakening of dilated heart muscle)
  7. Constipation
  8. Crepitations (noises are produced by the rubbing of parts one against the other)
  9. Deep vein thrombosis (blood clot in a major vein that usually develops in the legs and/or pelvis)
  10. Dizziness

male:

  1. Pain
  2. Burning sensation
  3. Pain in extremity
  4. Scar
  5. Skin disorder (skin disease)
  6. Skin hyperpigmentation (disorders affect the colour of your skin)
  7. Skin hypertrophy (skin cells enlarges)
  8. Skin induration (an abnormally hard spot or area on the skin)
  9. Skin tightness
  10. Ocular icterus (presence of jaundice seen in the sclera of the eye)

What are the common drug interactions of Bumex and Adalat, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

n/a

40-49:

  1. Haemolytic uraemic syndrome (blood clotting disease caused by e. coli infection, birth control pills, pneumonia, medications, and more)
  2. Urticaria (rash of round, red welts on the skin that itch intensely)
  3. Vomiting

50-59:

  1. Musculoskeletal pain (pain affects the bones, muscles, ligaments, tendons, and nerves)
  2. Nephrogenic systemic fibrosis (involves fibrosis of skin, joints, eyes due to kidney disease)
  3. Pain
  4. Pain in extremity
  5. Scar
  6. Skin disorder (skin disease)
  7. Skin hyperpigmentation (disorders affect the colour of your skin)
  8. Skin hypertrophy (skin cells enlarges)
  9. Skin induration (an abnormally hard spot or area on the skin)
  10. Skin tightness

60+:

  1. Gastrointestinal haemorrhage (bleeding gastrointestinal tract)
  2. Renal failure (kidney dysfunction)
  3. Oedema peripheral (superficial swelling)
  4. Pneumonitis (inflammation of the walls of the alveoli in the lungs)
  5. Sepsis (a severe blood infection that can lead to organ failure and death)
  6. Stupor (lack of critical cognitive function and level of consciousness)
  7. Urinary incontinence (inability to control the flow of urine and involuntary urination)
  8. Vomiting
  9. Dyspnoea (difficult or laboured respiration)
  10. Bradycardia (abnormally slow heart action)

What are the existing conditions these people have? *

  1. Nuclear Magnetic Resonance Imaging Brain: 5 people, 15.62%
  2. Pain: 4 people, 12.50%
  3. Pancytopenia (medical condition in which there is a reduction in the number of red and white blood cells, as well as platelets): 3 people, 9.38%
  4. Chest Pain: 3 people, 9.38%
  5. Atrial Fibrillation/flutter (atrial fibrillation and flutter are abnormal heart rhythms in which the atria, or upper chambers of the heart, are out of sync with the ventricles): 3 people, 9.38%
  6. Cough: 2 people, 6.25%

* Approximation only. Some reports may have incomplete information.

Do you take Bumex and Adalat?

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Related studies:

Effectiveness of, side effects of, and alternative drugs to the 2 drugs:

Browse all drug interactions of Bumex and Adalat:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Bumex:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all side effects of Adalat:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Bumex and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Adalat and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

How the study uses the data?

The study uses data from the FDA. It is based on bumetanide and nifedipine (the active ingredients of Bumex and Adalat, respectively), and Bumex and Adalat (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

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