Bumex and Fabrazyme drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Bumex (bumetanide) and Fabrazyme (agalsidase beta). Common drug interactions include arteriovenous fistula site complication among females and cardiac failure congestive among males.

The phase IV clinical study analyzes what interactions people have when they take Bumex and Fabrazyme. It is created by eHealthMe based on reports of 14 people who take the same drugs from the FDA, and is updated regularly.

What is Bumex?

Bumex has active ingredients of bumetanide. It is often used in swelling. eHealthMe is studying from 9,210 Bumex users. Check the latest studies of Bumex.

What is Fabrazyme?

Fabrazyme has active ingredients of agalsidase beta. eHealthMe is studying from 10,406 Fabrazyme users. Check the latest studies of Fabrazyme.



On Aug, 04, 2026

14 people who take Bumex and Fabrazyme together, and have interactions are studied.

Bumex and Fabrazyme drug interactions.

What are the common drug interactions of Bumex and Fabrazyme, by gender? *:

female:

  1. Arteriovenous fistula site complication
  2. Burning sensation
  3. Cellulitis (infection under the skin)
  4. Chills (felling of cold)
  5. Insomnia (sleeplessness)
  6. Nasopharyngitis (inflammation of the nasopharynx)
  7. Nausea (feeling of having an urge to vomit)

male:

  1. Cardiac failure congestive
  2. Disease recurrence
  3. Renal impairment (severely reduced kidney function)
  4. Restrictive cardiomyopathy (a condition in which the walls of the lower chambers of the heart (the ventricles) are abnormally rigid and lack the flexibility)
  5. Angina pectoris (chest pain due to ischemia of the heart muscle)
  6. Asthma
  7. Blood creatinine increased
  8. Cardiac disorder
  9. Cardiac failure
  10. Cellulitis (infection under the skin)

What are the common drug interactions of Bumex and Fabrazyme, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

n/a

40-49:

  1. Chills (felling of cold)
  2. Burning sensation
  3. Hypertension (high blood pressure)
  4. Insomnia (sleeplessness)
  5. Nasopharyngitis (inflammation of the nasopharynx)
  6. Nausea (feeling of having an urge to vomit)
  7. Oedema peripheral (superficial swelling)

50-59:

  1. Fluid overload (too much fluid in the blood)
  2. Restrictive cardiomyopathy (a condition in which the walls of the lower chambers of the heart (the ventricles) are abnormally rigid and lack the flexibility)
  3. Angina pectoris (chest pain due to ischemia of the heart muscle)
  4. Blood creatinine increased
  5. Cardiac disorder
  6. Cellulitis (infection under the skin)
  7. Cerebrovascular accident (sudden death of some brain cells due to lack of oxygen when the blood flow to the brain is impaired by blockage or rupture)
  8. Coagulopathy (blood's ability to clot is impaired)
  9. Convulsion (muscles contract and relax rapidly and repeatedly, resulting in an uncontrolled shaking of the body)
  10. Creatinine renal clearance decreased

60+:

  1. Arteriovenous fistula site complication
  2. Cellulitis (infection under the skin)

What are the existing conditions these people have? *

  1. Fabry's Disease (build up of a particular type of fat, called globotriaosylceramide, in the body's cells): 14 people, 100.00%

* Approximation only. Some reports may have incomplete information.

Do you take Bumex and Fabrazyme?

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Related studies:

Effectiveness of, side effects of, and alternative drugs to the 2 drugs:

Browse all drug interactions of Bumex and Fabrazyme:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Bumex:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all side effects of Fabrazyme:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Bumex and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Fabrazyme and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

How the study uses the data?

The study uses data from the FDA. It is based on bumetanide and agalsidase beta (the active ingredients of Bumex and Fabrazyme, respectively), and Bumex and Fabrazyme (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

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