Bumex and Sular drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Bumex (bumetanide) and Sular (nisoldipine). Common drug interactions include bradycardia among females and diarrhoea among males.

The phase IV clinical study analyzes what interactions people have when they take Bumex and Sular. It is created by eHealthMe based on reports of 18 people who take the same drugs from the FDA, and is updated regularly.

What is Bumex?

Bumex has active ingredients of bumetanide. It is often used in swelling. eHealthMe is studying from 9,210 Bumex users. Check the latest studies of Bumex.

What is Sular?

Sular has active ingredients of nisoldipine. It is often used in high blood pressure. eHealthMe is studying from 1,757 Sular users. Check the latest studies of Sular.



On Jul, 04, 2026

18 people who take Bumex and Sular together, and have interactions are studied.

Bumex and Sular drug interactions.

What are the common drug interactions of Bumex and Sular, by gender? *:

female:

  1. Bradycardia (abnormally slow heart action)
  2. Fatigue (feeling of tiredness)
  3. Hypotension (abnormally low blood pressure)
  4. Weakness
  5. Alanine aminotransferase increased
  6. Aspartate aminotransferase increased
  7. Asthenia (weakness)
  8. Biliary dilatation
  9. Blood alkaline phosphatase increased
  10. Blood calcium increased

male:

  1. Diarrhoea
  2. Pneumonia
  3. Blood urea increased
  4. Catheter related complication
  5. Haemoglobin decreased
  6. Malignant neoplasm progression (cancer tumour came back)
  7. Prostate cancer
  8. Sleep disorder
  9. Spleen disorder (disease of spleen)
  10. Bone pain

What are the common drug interactions of Bumex and Sular, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

n/a

40-49:

  1. Cardiac failure congestive
  2. Chest pain
  3. Fatigue (feeling of tiredness)
  4. Tachycardia (a heart rate that exceeds the range of 100 beats/min)

50-59:

  1. Catheter related complication

60+:

  1. Diarrhoea
  2. Pneumonia
  3. Alanine aminotransferase increased
  4. Aspartate aminotransferase increased
  5. Asthenia (weakness)
  6. Biliary dilatation
  7. Blood alkaline phosphatase increased
  8. Blood calcium increased
  9. Constipation
  10. Dermatitis (inflammation of the skin resulting from direct irritation by an external agent or an allergic reaction to it)

What are the existing conditions these people have? *

  1. Anaemia Of Chronic Disease: 5 people, 27.78%
  2. Iron Overload: 3 people, 16.67%
  3. Type 2 Diabetes: 1 person, 5.56%
  4. Osteoporosis (bones weak and more likely to break): 1 person, 5.56%
  5. Migraine (headache): 1 person, 5.56%
  6. Haemorrhoids (a swollen vein or group of veins in the region of the anus): 1 person, 5.56%
  7. Diabetes: 1 person, 5.56%
  8. Coronary Heart Disease (narrowing or blockage of the coronary arteries): 1 person, 5.56%
  9. Cardiac Failure Congestive: 1 person, 5.56%
  10. Back Pain: 1 person, 5.56%

* Approximation only. Some reports may have incomplete information.

Do you take Bumex and Sular?

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Related studies:

Effectiveness of, side effects of, and alternative drugs to the 2 drugs:

Browse all drug interactions of Bumex and Sular:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Bumex:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all side effects of Sular:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Bumex and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Sular and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

How the study uses the data?

The study uses data from the FDA. It is based on bumetanide and nisoldipine (the active ingredients of Bumex and Sular, respectively), and Bumex and Sular (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

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