Bupivacaine and Duramorph drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Bupivacaine (bupivacaine hydrochloride) and Duramorph (morphine sulfate). Common drug interactions include drug ineffective among females and abscess among males.

The phase IV clinical study analyzes what interactions people have when they take Bupivacaine and Duramorph. It is created by eHealthMe based on reports of 52 people who take the same drugs from the FDA, and is updated regularly.

What is Bupivacaine?

Bupivacaine has active ingredients of bupivacaine hydrochloride. eHealthMe is studying from 14,046 Bupivacaine users. Check the latest studies of Bupivacaine.

What is Duramorph?

Duramorph has active ingredients of morphine sulfate. eHealthMe is studying from 367 Duramorph users. Check the latest studies of Duramorph.

On Jul, 11, 2026

52 people who take Bupivacaine and Duramorph together, and have interactions are studied.

Bupivacaine and Duramorph drug interactions.

What are the common drug interactions of Bupivacaine and Duramorph, by gender? *:

female:

Drug ineffective
Anaesthetic complication
Hypothermia (body temperature drops below the required temperature for normal metabolism and body functions)
Discomfort
Skin exfoliation (removal of the oldest dead skin cells)
Unresponsive to stimuli
Urinary retention (the inability to completely or partially empty the bladder)
Vomiting
Pain
Tremor (trembling or shaking movements in one or more parts of your body)

male:

Abscess (pus)
Drug tolerance increased
Wound
Anaesthetic complication
Arthropathy
Brain injury
Chondropathy (disease of the cartilage)
Death
Hyperaesthesia
Metastases to spine (cancer spreads to spine)

What are the common drug interactions of Bupivacaine and Duramorph, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

Drug ineffective
Discomfort
Skin exfoliation (removal of the oldest dead skin cells)
Urinary retention (the inability to completely or partially empty the bladder)
Vomiting
Apnoea (suspension of external breathing)
Oxygen saturation decreased
Pruritus (severe itching of the skin)
Somnolence (a state of near-sleep, a strong desire for sleep)

30-39:

Drug ineffective
Hypothermia (body temperature drops below the required temperature for normal metabolism and body functions)
Unresponsive to stimuli
Asthenia (weakness)
Drug exposure during pregnancy
Meningitis bacterial (bacterial inflammation of the protective membranes covering the brain and spinal cord, known collectively as the meninges)
Sweating increased (excess sweating)
Abdominal pain lower
Blood glucose increased
Convulsion (muscles contract and relax rapidly and repeatedly, resulting in an uncontrolled shaking of the body)

40-49:

Anaesthetic complication
Drug ineffective
Blood pressure systolic increased
Cellulitis (infection under the skin)
Cellulitis gangrenous (localized inflammation of the soft or connective tissue with considerable mass of body tissue dies (necrosis))
Gangrene (body tissue dies)
Headache (pain in head)
Hypoaesthesia (reduced sense of touch or sensation)
Nausea (feeling of having an urge to vomit)
Necrotising fasciitis (an uncommon life-threatening soft-tissue infection)

50-59:

Burning sensation
Catheter site pain
Groin pain
Pain
Skin discolouration (change of skin colour)
Tremor (trembling or shaking movements in one or more parts of your body)

60+:

Anaesthetic complication
Arthropathy
Urinary incontinence (inability to control the flow of urine and involuntary urination)
Ataxia (loss of full control of bodily movements)
Back pain
Chondropathy (disease of the cartilage)
Chronic inflammatory demyelinating polyradiculoneuropathy (long lasting infection of nerves outside brain and spinal cord)
Fall
Neurogenic bladder (the normal function of the bladder is to store and empty urine in a coordinated, controlled fashion)
Paraplegia (paralysis of the legs and lower body)

What are the existing conditions these people have? *

Pain: 5 people, 9.62%

* Approximation only. Some reports may have incomplete information.

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