Buprenorphine and Vivitrol drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Buprenorphine (buprenorphine) and Vivitrol (naltrexone). Common drug interactions include drug dependence among females and cardiac failure congestive among males.

The phase IV clinical study analyzes what interactions people have when they take Buprenorphine and Vivitrol. It is created by eHealthMe based on reports of 22 people who take the same drugs from the FDA, and is updated regularly.

What is Buprenorphine?

Buprenorphine has active ingredients of buprenorphine. It is often used in opioid intoxication. eHealthMe is studying from 9,053 Buprenorphine users. Check the latest studies of Buprenorphine.

What is Vivitrol?

Vivitrol has active ingredients of naltrexone. It is often used in alcoholism. eHealthMe is studying from 25,129 Vivitrol users. Check the latest studies of Vivitrol.

On Jul, 12, 2026

22 people who take Buprenorphine and Vivitrol together, and have interactions are studied.

Buprenorphine and Vivitrol drug interactions.

What are the common drug interactions of Buprenorphine and Vivitrol, by gender? *:

female:

Drug dependence
Injection site bruising
Injection site mass
Injection site pain
Injection site reaction
Reproductive tract disorder (disease of reproductive system)
Weight decreased
Hypokalaemia (low potassium)

male:

Cardiac failure congestive
Injury
Abdominal pain
Dehydration (dryness resulting from the removal of water)
Euphoric mood (excessively happy but may become angry or irritable)
Muscle spasms (muscle contraction)
Nervousness
Restlessness (not able to rest)
Substance-induced psychotic disorder
Tachycardia (a heart rate that exceeds the range of 100 beats/min)

What are the common drug interactions of Buprenorphine and Vivitrol, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

Asthenia (weakness)
Chest pain
Cough
Diarrhoea
Feeling cold
Headache (pain in head)
Injection site pain
Injection site reaction
Limb discomfort (discomfort in leg)
Mass

30-39:

Injection site pain
Injection site reaction
Reproductive tract disorder (disease of reproductive system)
Weight decreased
Abdominal pain
Anxiety
Dehydration (dryness resulting from the removal of water)
Drug withdrawal syndrome (interfere with normal social, occupational, or other functioning. are not due to another medical condition, drug use, or discontinuation)
Euphoric mood (excessively happy but may become angry or irritable)
Hypokalaemia (low potassium)

40-49:

n/a

50-59:

Injury
Chest pain
Depressed level of consciousness
Dyspnoea (difficult or laboured respiration)
Myocardial infarction (destruction of heart tissue resulting from obstruction of the blood supply to the heart muscle)

60+:

Cardiac failure congestive

What are the existing conditions these people have? *

Drug Dependence: 7 people, 31.82%
Withdrawal Syndrome (a discontinuation syndrome is a set of symptoms occurred due to discontinuation of substance): 2 people, 9.09%
Stress And Anxiety: 2 people, 9.09%
Pain: 2 people, 9.09%
Insomnia (sleeplessness): 2 people, 9.09%
Drug Withdrawal Syndrome (interfere with normal social, occupational, or other functioning. are not due to another medical condition, drug use, or discontinuation): 2 people, 9.09%

* Approximation only. Some reports may have incomplete information.

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