Bupropion hydrochloride and Daliresp drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Bupropion hydrochloride (bupropion hydrochloride) and Daliresp (roflumilast). Common drug interactions include pollakiuria among females and anhedonia among males.

The phase IV clinical study analyzes what interactions people have when they take Bupropion hydrochloride and Daliresp. It is created by eHealthMe based on reports of 37 people who take the same drugs from the FDA, and is updated regularly.

What is Bupropion hydrochloride?

Bupropion hydrochloride has active ingredients of bupropion hydrochloride. It is often used in depression. eHealthMe is studying from 21,496 Bupropion hydrochloride users. Check the latest studies of Bupropion hydrochloride.

What is Daliresp?

Daliresp has active ingredients of roflumilast. It is often used in chronic obstructive pulmonary disease. eHealthMe is studying from 4,722 Daliresp users. Check the latest studies of Daliresp.



On Jul, 17, 2026

37 people who take Bupropion hydrochloride and Daliresp together, and have interactions are studied.

Bupropion hydrochloride and Daliresp drug interactions.

What are the common drug interactions of Bupropion Hydrochloride and Daliresp, by gender? *:

female:

  1. Pollakiuria (abnormally frequent passage of relatively small quantities or urine)
  2. Poor quality sleep
  3. Fatigue (feeling of tiredness)
  4. Nausea (feeling of having an urge to vomit)
  5. Headache (pain in head)
  6. Arthralgia (joint pain)
  7. Respiratory tract infection
  8. Chest discomfort
  9. Diarrhoea
  10. Gastritis (inflammation of stomach)

male:

  1. Anhedonia (inability to experience pleasure from activities usually found enjoyable)
  2. Bone density decreased
  3. Dizziness
  4. Fatigue (feeling of tiredness)
  5. Osteonecrosis (death of bone)
  6. Decreased appetite
  7. Nausea (feeling of having an urge to vomit)
  8. Chronic kidney disease
  9. Emotional distress
  10. Hip arthroplasty

What are the common drug interactions of Bupropion Hydrochloride and Daliresp, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

n/a

40-49:

n/a

50-59:

  1. Rash pruritic (redness with itching)
  2. Renal failure (kidney dysfunction)
  3. Renal impairment (severely reduced kidney function)
  4. Respiratory tract infection
  5. Scar
  6. Sputum discoloured
  7. Tremor (trembling or shaking movements in one or more parts of your body)
  8. Visual impairment
  9. Vomiting
  10. Wheezing (a high-pitched whistling sound made while you breath)

60+:

  1. Fatigue (feeling of tiredness)
  2. Headache (pain in head)
  3. Diarrhoea
  4. Hypoaesthesia oral (reduced sense of touch or sensation in mouth)
  5. Infusion related reaction
  6. Multiple allergies (allergy to multiple agents)
  7. Pain
  8. Paraesthesia oral (sensation of tingling, tickling, prickling, pricking, or burning of a person's oral with no apparent long-term physical effect)
  9. Procedural nausea
  10. Productive cough

What are the existing conditions these people have? *

  1. Asthma: 9 people, 24.32%
  2. Immunodeficiency Common Variable: 3 people, 8.11%
  3. Hiv Infection: 3 people, 8.11%
  4. Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 3 people, 8.11%
  5. Nausea (feeling of having an urge to vomit): 2 people, 5.41%
  6. Multiple Allergies (allergy to multiple agents): 2 people, 5.41%
  7. Migraine (headache): 2 people, 5.41%
  8. Infection: 2 people, 5.41%
  9. Hypogammaglobulinaemia (an abnormally low concentration of gamma globulin in the blood and increased risk of infection): 2 people, 5.41%
  10. High Blood Pressure: 2 people, 5.41%

* Approximation only. Some reports may have incomplete information.

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Related studies:

Effectiveness of, side effects of, and alternative drugs to the 2 drugs:

Browse all drug interactions of Bupropion hydrochloride and Daliresp:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Bupropion hydrochloride:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all side effects of Daliresp:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Bupropion hydrochloride and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Daliresp and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

How the study uses the data?

The study uses data from the FDA. It is based on bupropion hydrochloride and roflumilast (the active ingredients of Bupropion hydrochloride and Daliresp, respectively), and Bupropion hydrochloride and Daliresp (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

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