Buscopan and Alfenta drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Buscopan (hyoscine butylbromide) and Alfenta (alfentanil hydrochloride). Common drug interactions include colitis among females.

The phase IV clinical study analyzes what interactions people have when they take Buscopan and Alfenta. It is created by eHealthMe based on reports of 22 people who take the same drugs from the FDA, and is updated regularly.

What is Buscopan?

Buscopan has active ingredients of hyoscine butylbromide. eHealthMe is studying from 4,828 Buscopan users. Check the latest studies of Buscopan.

What is Alfenta?

Alfenta has active ingredients of alfentanil hydrochloride. eHealthMe is studying from 1,508 Alfenta users. Check the latest studies of Alfenta.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.



On Aug, 28, 2026

22 people who take Buscopan and Alfenta together, and have interactions are studied.

Buscopan and Alfenta drug interactions.

What are the common drug interactions of Buscopan and Alfenta, by gender? *:

female:

  1. Colitis (inflammation of colon)
  2. Diarrhoea
  3. Oesophagitis (inflammation of oesophagus)
  4. Rash
  5. Hydronephrosis (water inside the kidney)
  6. Abdominal pain
  7. Colitis ischaemic (due to infection of intestine impaired blood supply to colon)
  8. Neutropenic sepsis (whole body infection is caused by a condition in which the number of white blood cells (called neutrophils) in the blood is low. neutrophils help the body to fight infection)
  9. Pneumonia
  10. Vomiting

male:

n/a

What are the common drug interactions of Buscopan and Alfenta, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

n/a

40-49:

  1. Vomiting
  2. Diarrhoea
  3. Peritonitis (inflammation of the peritoneum, the thin tissue that lines the inner wall of the abdomen and covers most of the abdominal organs)
  4. Rash
  5. Colitis (inflammation of colon)
  6. Abdominal pain
  7. Colitis ischaemic (due to infection of intestine impaired blood supply to colon)
  8. Neutropenic sepsis (whole body infection is caused by a condition in which the number of white blood cells (called neutrophils) in the blood is low. neutrophils help the body to fight infection)
  9. Pneumonia

50-59:

n/a

60+:

  1. Deep vein thrombosis (blood clot in a major vein that usually develops in the legs and/or pelvis)
  2. Gastrointestinal haemorrhage (bleeding gastrointestinal tract)
  3. Oesophagitis (inflammation of oesophagus)
  4. Diarrhoea
  5. Hydronephrosis (water inside the kidney)

What are the existing conditions these people have? *

  1. Pain: 19 people, 86.36%
  2. Depression: 18 people, 81.82%
  3. Nausea (feeling of having an urge to vomit): 15 people, 68.18%
  4. Diarrhea: 14 people, 63.64%
  5. Blood Magnesium Decreased: 12 people, 54.55%
  6. Breast Cancer Metastatic: 12 people, 54.55%
  7. Neutropenic Sepsis (whole body infection is caused by a condition in which the number of white blood cells (called neutrophils) in the blood is low. neutrophils help the body to fight infection): 11 people, 50.00%
  8. Pneumonia: 10 people, 45.45%
  9. Colitis Ischaemic (due to infection of intestine impaired blood supply to colon): 7 people, 31.82%
  10. Nausea And Vomiting: 6 people, 27.27%

* Approximation only. Some reports may have incomplete information.

Do you take Buscopan and Alfenta?

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Related studies:

Effectiveness of, side effects of, and alternative drugs to the 2 drugs:

Browse all drug interactions of Buscopan and Alfenta:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Buscopan:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all side effects of Alfenta:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Buscopan and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Alfenta and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

How the study uses the data?

The study uses data from the FDA. It is based on hyoscine butylbromide and alfentanil hydrochloride (the active ingredients of Buscopan and Alfenta, respectively), and Buscopan and Alfenta (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.



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