Buscopan and Augmentin drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Buscopan (hyoscine butylbromide) and Augmentin (amoxicillin; clavulanate potassium). Common drug interactions include haemorrhage among females and cerebellar infarction among males.

The phase IV clinical study analyzes what interactions people have when they take Buscopan and Augmentin. It is created by eHealthMe based on reports of 70 people who take the same drugs from the FDA, and is updated regularly.

What is Buscopan?

Buscopan has active ingredients of hyoscine butylbromide. eHealthMe is studying from 4,828 Buscopan users. Check the latest studies of Buscopan.

What is Augmentin?

Augmentin has active ingredients of amoxicillin; clavulanate potassium. It is often used in sinusitis. eHealthMe is studying from 42,620 Augmentin users. Check the latest studies of Augmentin.

On Jul, 19, 2026

70 people who take Buscopan and Augmentin together, and have interactions are studied.

Buscopan and Augmentin drug interactions.

What are the common drug interactions of Buscopan and Augmentin, by gender? *:

female:

Haemorrhage (bleeding)
Leukopenia (less number of white blood cells in blood)
Haematochezia (passage of stools containing blood)
Aortic rupture
Contusion (a type of hematoma of tissue in which capillaries)
Dehydration (dryness resulting from the removal of water)
Fatigue (feeling of tiredness)
Hepatitis acute
Hypokalaemia (low potassium)
Intestinal ischaemia (decreased supply of oxygenated blood to the intestines)

male:

Cerebellar infarction (impaired blood circulation to cerebellum)
Cough
Blood creatinine increased
Cardio-respiratory arrest (sudden dysfunction of heart and lungs)
Dyspnoea (difficult or laboured respiration)
Foetal exposure during pregnancy (exposing your unborn child to contraindicated in pregnancy leads birth defect)
Gastrointestinal haemorrhage (bleeding gastrointestinal tract)
Haemangioma (noncancerous, abnormally dense collections of dilated small blood vessels that may occur in the skin or internal organs)
Haemoptysis (blood-stained sputum from the bronchi, larynx, trachea, or lungs)
Hypoxia (low oxygen in tissues)

What are the common drug interactions of Buscopan and Augmentin, by age (0-1 to 60+)? *:

0-1:

Abdominal pain
Cough
Foetal exposure during pregnancy (exposing your unborn child to contraindicated in pregnancy leads birth defect)
Haemangioma (noncancerous, abnormally dense collections of dilated small blood vessels that may occur in the skin or internal organs)
Influenza
Otitis media (inflammation of the middle ear)
Pyrexia (fever)
Thermal burn (burn by heat)
Upper respiratory tract infection
Viral upper respiratory tract infection

2-9:

n/a

10-19:

Alveolitis (inflammation in the socket of a tooth)
Cardio-respiratory arrest (sudden dysfunction of heart and lungs)
Convulsion (muscles contract and relax rapidly and repeatedly, resulting in an uncontrolled shaking of the body)
Cough
Dyspnoea (difficult or laboured respiration)
Haemoptysis (blood-stained sputum from the bronchi, larynx, trachea, or lungs)
Hypoxia (low oxygen in tissues)
Respiratory distress (difficulty in breathing)
Malignant neoplasm progression (cancer tumour came back)
Partial seizures (seizures which affect only a part of the brain at onset)

20-29:

Hepatitis acute
Cough
Fatigue (feeling of tiredness)
Abdominal pain
Anal ulcer
Blister (small pocket of fluid within the upper layers of the skin caused by forceful rubbing (friction), burning, freezing, chemical exposure)
Blood creatinine increased
Blood urea increased
Coma (state of unconsciousness lasting more than six hours)
Dermatitis (inflammation of the skin resulting from direct irritation by an external agent or an allergic reaction to it)

30-39:

Abdominal pain upper
Abortion spontaneous (naturally occurring miscarriage)
Cholelithiasis (the presence or formation of gallstones in the gallbladder or bile ducts)
Dermatitis acneiform (dermatoses including acne vulgaris, rosacea, folliculitis, and perioral dermatitis)
Drug specific antibody present
Foetal death (death of foetus)
Gallbladder disorder
Inflammatory marker increased
Intestinal resection

40-49:

Large intestine perforation (hole in large intestine)
Malaise (a feeling of general discomfort or uneasiness)
Pneumonia
Red blood cell count decreased
Small intestine carcinoma (cancer tumour of small intestine)
Vomiting
Cerebellar infarction (impaired blood circulation to cerebellum)
Abdominal pain
Bladder spasm
Blood alkaline phosphatase increased

50-59:

Abscess (pus)
Gastrointestinal haemorrhage (bleeding gastrointestinal tract)
Ileus (a painful obstruction of the ileum or other part of the intestine)
Malignant neoplasm progression (cancer tumour came back)
Abdominal pain upper
Ascites (accumulation of fluid in the abdominal cavity)
Constipation
Decreased appetite
Dry eye (lack of adequate tears)
Fatigue (feeling of tiredness)

60+:

Death
Febrile neutropenia (fever with reduced white blood cells)
Post procedural haemorrhage (post procedural bleeding)
Rectal ulcer (ulcer of rectum)
Wound infection
Blood sodium decreased
Haematochezia (passage of stools containing blood)
Malignant neoplasm progression (cancer tumour came back)
Respiratory failure (inadequate gas exchange by the respiratory system)
Sepsis (a severe blood infection that can lead to organ failure and death)

What are the existing conditions these people have? *

Nausea (feeling of having an urge to vomit): 19 people, 27.14%
Abdominal Pain: 18 people, 25.71%
High Blood Pressure: 13 people, 18.57%
Constipation: 13 people, 18.57%
Diarrhea: 13 people, 18.57%
Pain: 12 people, 17.14%
Chest Pain: 11 people, 15.71%
Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 11 people, 15.71%
Anaemia (lack of blood): 10 people, 14.29%
Abdominal Pain Upper: 9 people, 12.86%

* Approximation only. Some reports may have incomplete information.

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