Buscopan and Ms contin drug interactions - a phase IV clinical study of FDA data
Summary:
Drug interactions are reported among people who take Buscopan (hyoscine butylbromide) and Ms contin (morphine sulfate). Common drug interactions include malignant neoplasm progression among females and hypoaesthesia among males.
The phase IV clinical study analyzes what interactions people have when they take Buscopan and Ms contin. It is created by eHealthMe based on reports of 14 people who take the same drugs from the FDA, and is updated regularly.
What is Buscopan?
Buscopan has active ingredients of hyoscine butylbromide. eHealthMe is studying from 4,828 Buscopan users. Check the latest studies of Buscopan.
What is Ms contin?
Ms contin has active ingredients of morphine sulfate. It is often used in pain. eHealthMe is studying from 69,289 Ms contin users. Check the latest studies of Ms contin.
eHealthMe: drug outcomes in the real world
eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.
14 people who take Buscopan and Ms contin together, and have interactions are studied.

What are the common drug interactions of Buscopan and Ms Contin, by gender? *:
female:
- Malignant neoplasm progression (cancer tumour came back)
- Enterocolitis (inflammation of the digestive tract, involving enteritis of the small intestine and colitis of the colon)
- Neutropenia (an abnormally low number of neutrophils)
- Oedema peripheral (superficial swelling)
- Pneumonia
- Pyelonephritis (inflammation of kidney caused by bacteria)
- Cervix carcinoma (cancer of cervix)
- Nausea (feeling of having an urge to vomit)
- Somnolence (a state of near-sleep, a strong desire for sleep)
- Thirst
male:
- Hypoaesthesia (reduced sense of touch or sensation)
- Insomnia (sleeplessness)
- Liver disorder (liver diseases)
- Malaise (a feeling of general discomfort or uneasiness)
- Malignant neoplasm progression (cancer tumour came back)
- Metastases to bone (cancer spreads to bone)
- Nausea (feeling of having an urge to vomit)
- Neoplasm malignant (cancer tumour)
- Neutrophil percentage increased
- Oesophageal candidiasis (fungal infection of oesophagus)
What are the common drug interactions of Buscopan and Ms Contin, by age (0-1 to 60+)? *:
0-1:
n/a
2-9:
n/a
10-19:
n/a
20-29:
- Abdominal pain
- Chills (felling of cold)
- Hypoaesthesia (reduced sense of touch or sensation)
- Malignant neoplasm progression (cancer tumour came back)
- Pyrexia (fever)
30-39:
- Chest pain
- Dyspnoea (difficult or laboured respiration)
- Hypoaesthesia (reduced sense of touch or sensation)
- Mobility decreased (ability to move is reduced)
- Muscular weakness (muscle weakness)
- Poor venous access
40-49:
n/a
50-59:
- Enterocolitis (inflammation of the digestive tract, involving enteritis of the small intestine and colitis of the colon)
- Neutropenia (an abnormally low number of neutrophils)
- Oedema peripheral (superficial swelling)
- Cardiac flutter (abnormal heart rhythm)
- Infusion related reaction
- Malignant neoplasm progression (cancer tumour came back)
60+:
- Malignant neoplasm progression (cancer tumour came back)
- Pneumonia
- Inflammation
- Insomnia (sleeplessness)
- Liver disorder (liver diseases)
- Neutrophil percentage increased
- Vomiting
- Pyelonephritis (inflammation of kidney caused by bacteria)
- Cervix carcinoma (cancer of cervix)
- Nausea (feeling of having an urge to vomit)
What are the existing conditions these people have? *
- Cancer Pain: 6 people, 42.86%
- Insomnia (sleeplessness): 4 people, 28.57%
- Constipation: 4 people, 28.57%
- Nausea And Vomiting: 3 people, 21.43%
- Hypothyroidism (abnormally low activity of the thyroid gland, resulting in retardation of growth and mental development): 3 people, 21.43%
- Enterocolitis (inflammation of the digestive tract, involving enteritis of the small intestine and colitis of the colon): 3 people, 21.43%
- Stomatitis (inflammation of mucous membrane of mouth): 3 people, 21.43%
- Lung Cancer - Non-Small Cell (lung cancer): 3 people, 21.43%
- Dry Skin: 3 people, 21.43%
- Diarrhea: 3 people, 21.43%
* Approximation only. Some reports may have incomplete information.
Do you take Buscopan and Ms contin?
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Related studies:
Effectiveness of, side effects of, and alternative drugs to the 2 drugs:
Browse all drug interactions of Buscopan and Ms contin:
a b c d e f g h i j k l m n o p q r s t u v w x y zSub-studies by gender and age:
Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Browse all side effects of Buscopan:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all side effects of Ms contin:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Buscopan and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Ms contin and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zRelated publications that referenced our studies
- Rasmy A, Rahal M, Kisana M, Ahmad S, Salah A, "Morphine induced thrombocytopenia: A case report", Journal of Case Reports and Images in Oncology, 2015 Dec .
- Rasmy A, Rahal M, Kisana M, Ahmad S, Salah A, "Morphine induced thrombocytopenia: A case report", Journal of Case Reports and Images in Oncology, 2015 Dec .
How the study uses the data?
The study uses data from the FDA. It is based on hyoscine butylbromide and morphine sulfate (the active ingredients of Buscopan and Ms contin, respectively), and Buscopan and Ms contin (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.
How to use the study?
DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.
Who is eHealthMe?
With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).
WARNING, DISCLAIMER, USE FOR PUBLICATION
WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.
DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.
If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.
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