Buspar and Codeine sulfate drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Buspar (buspirone hydrochloride) and Codeine sulfate (codeine sulfate). Common drug interactions include antiphospholipid syndrome among females and blood triglycerides increased among males.

The phase IV clinical study analyzes what interactions people have when they take Buspar and Codeine sulfate. It is created by eHealthMe based on reports of 31 people who take the same drugs from the FDA, and is updated regularly.

What is Buspar?

Buspar has active ingredients of buspirone hydrochloride. It is often used in stress and anxiety. eHealthMe is studying from 20,462 Buspar users. Check the latest studies of Buspar.

What is Codeine sulfate?

Codeine sulfate has active ingredients of codeine sulfate. It is often used in pain. eHealthMe is studying from 4,510 Codeine sulfate users. Check the latest studies of Codeine sulfate.



On Jul, 09, 2026

31 people who take Buspar and Codeine sulfate together, and have interactions are studied.

Buspar and Codeine sulfate drug interactions.

What are the common drug interactions of Buspar and Codeine Sulfate, by gender? *:

female:

  1. Antiphospholipid syndrome (disorder that manifests clinically as recurrent venous or arterial thrombosis and/or fetal loss)
  2. Arteriospasm coronary (spasm of the large- or medium-sized coronary arteries)
  3. Asthma
  4. Astigmatism (refractive error of the eye in which parallel rays of light from an external source do not converge on a single focal point on the retina)
  5. Azotaemia (excess of urea or other nitrogenous compounds in the blood)
  6. Dizziness
  7. Fatigue (feeling of tiredness)
  8. Drug ineffective
  9. Abdominal pain
  10. Cystitis interstitial (unknown cause characterized by bladder pain)

male:

  1. Blood triglycerides increased
  2. Bursitis (inflammation of a bursa, typically one in the knee, elbow, or shoulder)
  3. Type 2 diabetes mellitus
  4. Weight increased
  5. Cardiac disorder
  6. Death
  7. Diarrhoea haemorrhagic (bloody diarrhoea)
  8. Haemorrhage subcutaneous (bleeding from skin)
  9. High density lipoprotein increased
  10. Nodule (a growth of abnormal tissue)

What are the common drug interactions of Buspar and Codeine Sulfate, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

n/a

40-49:

  1. Diabetic ketoacidosis (diabetic ketoacidosis (dka) is high concentrations of ketone bodies)
  2. Diabetic nephropathy (diabetic kidney disease)
  3. Diabetic retinopathy (damage to the retina caused by complications of diabetes)
  4. Diarrhoea haemorrhagic (bloody diarrhoea)
  5. Diastolic dysfunction
  6. Drug hypersensitivity
  7. Dyspepsia (indigestion)
  8. Dysphagia (a condition in which swallowing is difficult or painful)
  9. Dyspnoea (difficult or laboured respiration)
  10. Ear pain

50-59:

  1. Dizziness
  2. Fungal infection
  3. Fatigue (feeling of tiredness)
  4. Acute respiratory distress syndrome
  5. Altered state of consciousness (altered state of mind)
  6. Anaemia of malignant disease
  7. Anhedonia (inability to experience pleasure from activities usually found enjoyable)
  8. Aortic valve incompetence
  9. Atelectasis (partial or complete collapse of the lung)
  10. Atrial fibrillation (fibrillation of the muscles of the atria of the heart)

60+:

  1. Drug hypersensitivity

What are the existing conditions these people have? *

  1. Narcolepsy (brain's inability to regulate sleep-wake cycles normally): 18 people, 58.06%
  2. Hypersensitivity: 18 people, 58.06%
  3. High Blood Pressure: 13 people, 41.94%
  4. Ill-Defined Disorder: 11 people, 35.48%
  5. Thrombosis (formation of a blood clot inside a blood vessel): 8 people, 25.81%
  6. Cataplexy (loss of muscle tone accompanied by full conscious awareness): 8 people, 25.81%
  7. Muscle Aches (muscle pain): 6 people, 19.35%
  8. Hormone Level Abnormal: 6 people, 19.35%
  9. Cystitis Interstitial (unknown cause characterized by bladder pain): 6 people, 19.35%
  10. Constipation: 6 people, 19.35%

* Approximation only. Some reports may have incomplete information.

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Related studies:

Effectiveness of, side effects of, and alternative drugs to the 2 drugs:

Browse all drug interactions of Buspar and Codeine sulfate:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Buspar:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all side effects of Codeine sulfate:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Buspar and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Codeine sulfate and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

How the study uses the data?

The study uses data from the FDA. It is based on buspirone hydrochloride and codeine sulfate (the active ingredients of Buspar and Codeine sulfate, respectively), and Buspar and Codeine sulfate (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

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