Buspar and Letrozole drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Buspar (buspirone hydrochloride) and Letrozole (letrozole). Common drug interactions include nausea among females.

The phase IV clinical study analyzes what interactions people have when they take Buspar and Letrozole. It is created by eHealthMe based on reports of 13 people who take the same drugs from the FDA, and is updated regularly.

What is Buspar?

Buspar has active ingredients of buspirone hydrochloride. It is often used in stress and anxiety. eHealthMe is studying from 20,462 Buspar users. Check the latest studies of Buspar.

What is Letrozole?

Letrozole has active ingredients of letrozole. It is often used in breast cancer. eHealthMe is studying from 54,125 Letrozole users. Check the latest studies of Letrozole.

On Jul, 08, 2026

13 people who take Buspar and Letrozole together, and have interactions are studied.

What are the common drug interactions of Buspar and Letrozole, by gender? *:

female:

Nausea (feeling of having an urge to vomit)
Fatigue (feeling of tiredness)
Malaise (a feeling of general discomfort or uneasiness)
Neutrophil count decreased (less than normal number of neutrophil a type of blood cell)
Panic reaction
Peripheral swelling
Aspartate aminotransferase increased
Blood glucose increased
Blood urea increased
Dyspnoea (difficult or laboured respiration)

male:

n/a

What are the common drug interactions of Buspar and Letrozole, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

Abortion spontaneous (naturally occurring miscarriage)
Maternal exposure during pregnancy (use of substance during pregnancy)

40-49:

n/a

50-59:

Headache (pain in head)
Middle insomnia (difficulty returning to sleep after awakening either in the middle of the night)
Nausea (feeling of having an urge to vomit)
Neoplasm progression (growth of tumour)
Arterial thrombosis (formation of a blood clot inside a blood vessel, obstructing the flow of blood through the circulatory system)
Constipation
Cough
Fatigue (feeling of tiredness)
Joint swelling
Oedema (fluid collection in tissue)

60+:

Fatigue (feeling of tiredness)
White blood cell count decreased
Blood glucose increased
Blood urea increased
Dyspnoea (difficult or laboured respiration)
Fall
Hypoaesthesia (reduced sense of touch or sensation)
Somnolence (a state of near-sleep, a strong desire for sleep)
Cough
Pharyngeal erythema (pharyngeal redness)

What are the existing conditions these people have? *

Depression: 3 people, 23.08%
Breast Cancer Stage Iv: 2 people, 15.38%
Breast Cancer Stage Ii: 1 person, 7.69%
Arthritis (form of joint disorder that involves inflammation of one or more joints): 1 person, 7.69%
Asthma: 1 person, 7.69%
Back Pain: 1 person, 7.69%
Bipolar Disorder (mood disorder): 1 person, 7.69%
Breast Cancer Female: 1 person, 7.69%
Breast Cancer Metastatic: 1 person, 7.69%
Type 2 Diabetes: 1 person, 7.69%

* Approximation only. Some reports may have incomplete information.

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