Buspar and Memantine drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Buspar (buspirone hydrochloride) and Memantine (memantine). Common drug interactions include drug ineffective among females and muscular weakness among males.

The phase IV clinical study analyzes what interactions people have when they take Buspar and Memantine. It is created by eHealthMe based on reports of 20 people who take the same drugs from the FDA, and is updated regularly.

What is Buspar?

Buspar has active ingredients of buspirone hydrochloride. It is often used in stress and anxiety. eHealthMe is studying from 20,462 Buspar users. Check the latest studies of Buspar.

What is Memantine?

Memantine has active ingredients of memantine. It is often used in alzheimer's disease. eHealthMe is studying from 10,266 Memantine users. Check the latest studies of Memantine.



On Jul, 12, 2026

20 people who take Buspar and Memantine together, and have interactions are studied.

Buspar and Memantine drug interactions.

What are the common drug interactions of Buspar and Memantine, by gender? *:

female:

  1. Drug ineffective
  2. General physical health deterioration (weak health status)
  3. Alopecia (absence of hair from areas of the body)
  4. Back pain
  5. Blood cholesterol increased
  6. Confusional state
  7. Death
  8. Dehydration (dryness resulting from the removal of water)
  9. Delirium (wild excitement)
  10. Drooling (drop saliva uncontrollably from the mouth)

male:

  1. Muscular weakness (muscle weakness)
  2. Amnesia (deficit in memory caused by brain damage, disease, or psychological trauma)
  3. Gait disturbance
  4. Headache (pain in head)
  5. Memory impairment
  6. Mental impairment (a condition affecting the body, perhaps through sight or hearing loss, a mobility difficulty or a health condition)
  7. Microangiopathy (disease of the capillaries (very small blood vessels), in which the capillary walls become so thick and weak that they bleed, leak protein)
  8. Neoplasm malignant (cancer tumour)
  9. Neuropathy peripheral (surface nerve damage)
  10. Speech disorder

What are the common drug interactions of Buspar and Memantine, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

n/a

40-49:

  1. Blood cholesterol increased
  2. Hypotension (abnormally low blood pressure)
  3. Mood altered (changes in mood)
  4. Personality change
  5. Restlessness (not able to rest)
  6. Weight increased

50-59:

  1. Anger
  2. Delusion (a false belief or opinion)
  3. Dementia with lewy bodies (progressive degenerative disease or syndrome of the brain)
  4. Drug ineffective
  5. Muscular weakness (muscle weakness)
  6. Schizophrenia (a mental disorder characterized by a breakdown of thought processes)
  7. Therapeutic response unexpected
  8. White blood cell count increased

60+:

  1. Amnesia (deficit in memory caused by brain damage, disease, or psychological trauma)
  2. Aphasia (damage to the parts of the brain that control language)
  3. Gait disturbance
  4. General physical health deterioration (weak health status)
  5. Headache (pain in head)
  6. Memory impairment
  7. Mental impairment (a condition affecting the body, perhaps through sight or hearing loss, a mobility difficulty or a health condition)
  8. Microangiopathy (disease of the capillaries (very small blood vessels), in which the capillary walls become so thick and weak that they bleed, leak protein)
  9. Muscular weakness (muscle weakness)
  10. Neoplasm malignant (cancer tumour)

What are the existing conditions these people have? *

  1. Parkinson's Disease: 4 people, 20.00%
  2. Pain: 4 people, 20.00%
  3. Delusion (a false belief or opinion): 4 people, 20.00%
  4. Hallucinations (sensations that appear real but are created by your mind): 4 people, 20.00%
  5. Epilepsy (common and diverse set of chronic neurological disorders characterized by seizures): 3 people, 15.00%
  6. Seizures (abnormal excessive or synchronous neuronal activity in the brain): 3 people, 15.00%
  7. Depression: 3 people, 15.00%
  8. Macular Degeneration (painless eye condition that leads to the gradual loss of central vision): 3 people, 15.00%
  9. High Blood Pressure: 2 people, 10.00%
  10. Tardive Dyskinesia (a disorder that involves involuntary movements): 2 people, 10.00%

* Approximation only. Some reports may have incomplete information.

Do you take Buspar and Memantine?

- Personalize this study to your gender, age, symptoms and drugs
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously



Related studies:

Effectiveness of, side effects of, and alternative drugs to the 2 drugs:

Browse all drug interactions of Buspar and Memantine:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Buspar:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all side effects of Memantine:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Buspar and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Memantine and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

How the study uses the data?

The study uses data from the FDA. It is based on buspirone hydrochloride and memantine (the active ingredients of Buspar and Memantine, respectively), and Buspar and Memantine (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.



Recent studies on eHealthMe: