Buspar and Ranexa drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Buspar (buspirone hydrochloride) and Ranexa (ranolazine). Common drug interactions include chronic kidney disease among females and acute myocardial infarction among males.

The phase IV clinical study analyzes what interactions people have when they take Buspar and Ranexa. It is created by eHealthMe based on reports of 34 people who take the same drugs from the FDA, and is updated regularly.

What is Buspar?

Buspar has active ingredients of buspirone hydrochloride. It is often used in stress and anxiety. eHealthMe is studying from 20,462 Buspar users. Check the latest studies of Buspar.

What is Ranexa?

Ranexa has active ingredients of ranolazine. It is often used in angina. eHealthMe is studying from 11,758 Ranexa users. Check the latest studies of Ranexa.

On Jul, 02, 2026

34 people who take Buspar and Ranexa together, and have interactions are studied.

What are the common drug interactions of Buspar and Ranexa, by gender? *:

female:

Chronic kidney disease
Renal failure (kidney dysfunction)
Renal impairment (severely reduced kidney function)
Dehydration (dryness resulting from the removal of water)
Hypotension (abnormally low blood pressure)
Nephrogenic anaemia (anaemia due to kidney disease)
Weight decreased
Diarrhoea
Dizziness
Fall

male:

Acute myocardial infarction (acute heart attack)
Back pain
Musculoskeletal pain (pain affects the bones, muscles, ligaments, tendons, and nerves)
Pneumonia staphylococcal (pneumonia staphylococcal infections are usually caused by the organism staphylococcus aureus)
Respiratory failure (inadequate gas exchange by the respiratory system)
Sepsis (a severe blood infection that can lead to organ failure and death)
Shock haemorrhagic (a life-threatening condition with symptoms like low blood pressure, weakness, shallow breathing, cold, clammy skin due to excess bleeding)
Cardiac disorder
Chronic kidney disease
Heart rate increased

What are the common drug interactions of Buspar and Ranexa, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

Chronic kidney disease
Renal failure (kidney dysfunction)

40-49:

n/a

50-59:

Gait disturbance
Drug hypersensitivity
Acute myocardial infarction (acute heart attack)
Back pain
Cardiac failure congestive
Encephalopathy (functioning of the brain is affected by some agent or condition)
Fall
Gastric ulcer haemorrhage (bleeding ulcer of stomach)
Haemoptysis (blood-stained sputum from the bronchi, larynx, trachea, or lungs)
Hypokalaemia (low potassium)

60+:

Chronic kidney disease
Renal failure (kidney dysfunction)
Glycosylated haemoglobin increased
Haemorrhagic anaemia (anaemia due to excessive bleeding)
Hot flush (sudden feelings of heat)
Hyperhidrosis (abnormally increased sweating)
Hyperkalaemia (damage to or disease of the kidney)
Hypomagnesaemia (electrolyte disturbance in which there is an abnormally low level of magnesium in the blood)
Hypophagia (reduced food intake)
Hypotension (abnormally low blood pressure)

What are the existing conditions these people have? *

Pain: 10 people, 29.41%
High Blood Pressure: 7 people, 20.59%
Wheezing (a high-pitched whistling sound made while you breath): 6 people, 17.65%
Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 6 people, 17.65%
High Blood Cholesterol: 6 people, 17.65%
Depression: 5 people, 14.71%
Rheumatoid Arthritis (a chronic progressive disease causing inflammation in the joints): 5 people, 14.71%
Diabetes: 4 people, 11.76%
Nausea (feeling of having an urge to vomit): 4 people, 11.76%
Hypersensitivity: 4 people, 11.76%

* Approximation only. Some reports may have incomplete information.

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