Buspar and Seroquel xr drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Buspar (buspirone hydrochloride) and Seroquel xr (quetiapine fumarate). Common drug interactions include diarrhoea among females and insomnia among males.

The phase IV clinical study analyzes what interactions people have when they take Buspar and Seroquel xr. It is created by eHealthMe based on reports of 77 people who take the same drugs from the FDA, and is updated regularly.

What is Buspar?

Buspar has active ingredients of buspirone hydrochloride. It is often used in stress and anxiety. eHealthMe is studying from 20,462 Buspar users. Check the latest studies of Buspar.

What is Seroquel xr?

Seroquel xr has active ingredients of quetiapine fumarate. It is often used in bipolar disorder. eHealthMe is studying from 11,825 Seroquel xr users. Check the latest studies of Seroquel xr.

On Jul, 06, 2026

77 people who take Buspar and Seroquel xr together, and have interactions are studied.

Buspar and Seroquel xr drug interactions.

What are the common drug interactions of Buspar and Seroquel Xr, by gender? *:

female:

Diarrhoea
Altered state of consciousness (altered state of mind)
Aphagia (inability or refusal to swallow)
Swollen tongue (swelling of tongue)
Abdominal discomfort
Fall
Headache (pain in head)
Dizziness
Decreased appetite
Amnesia (deficit in memory caused by brain damage, disease, or psychological trauma)

male:

Insomnia (sleeplessness)
Drug ineffective
Aggression
Alanine aminotransferase increased
Alcohol withdrawal syndrome
Aspartate aminotransferase increased
Blood pressure increased
Drug level decreased
Drug withdrawal syndrome (interfere with normal social, occupational, or other functioning. are not due to another medical condition, drug use, or discontinuation)
Gynaecomastia (enlargement of the gland tissue of the male breast)

What are the common drug interactions of Buspar and Seroquel Xr, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

Fatigue (feeling of tiredness)
Asthenia (weakness)
Depressed mood
Dyspnoea (difficult or laboured respiration)
Furuncle (infection of the hair follicle)
Hypersensitivity
Hypothyroidism (abnormally low activity of the thyroid gland, resulting in retardation of growth and mental development)
Impaired work ability
Influenza like illness
Insomnia (sleeplessness)

30-39:

Loss of consciousness
Fatigue (feeling of tiredness)
Blood pressure increased
Aggression
Alanine aminotransferase increased
Alcohol withdrawal syndrome
Aspartate aminotransferase increased
Drug level decreased
Drug withdrawal syndrome (interfere with normal social, occupational, or other functioning. are not due to another medical condition, drug use, or discontinuation)
Gynaecomastia (enlargement of the gland tissue of the male breast)

40-49:

Insomnia (sleeplessness)
Weight increased
Adverse event
Hypertonic bladder (bladder-storage function that causes a sudden urge to urinate)
Malaise (a feeling of general discomfort or uneasiness)
Mood altered (changes in mood)
Underweight
Accident
Amnesia (deficit in memory caused by brain damage, disease, or psychological trauma)
Asthma

50-59:

Immunodeficiency
Infection
Liver tenderness (pain and discomfort in liver when touched)
Mouth haemorrhage (bleeding from mouth)
Neoplasm malignant (cancer tumour)
Oedema peripheral (superficial swelling)
Radiation injury (injuries are caused by radiation)
Staphylococcal infection (an infection with staphylococcus bacteria)
Swelling
Swelling face

60+:

Weight increased
Dyspnoea (difficult or laboured respiration)
Aphagia (inability or refusal to swallow)
Asthma
Drug ineffective
Dry mouth
Dysphagia (a condition in which swallowing is difficult or painful)
Nasal congestion (blockage of the nasal passages usually due to membranes lining the nose becoming swollen from inflamed blood vessels)
Nightmare (unpleasant dream)
Seasonal allergy (allergic condition due to certain season)

What are the existing conditions these people have? *

Depression: 33 people, 42.86%
Sleep Disorder: 12 people, 15.58%
Pain: 10 people, 12.99%
High Blood Cholesterol: 9 people, 11.69%
High Blood Pressure: 8 people, 10.39%
Insomnia (sleeplessness): 7 people, 9.09%
Bipolar I Disorder (mood disorder that is characterized by at least one manic or mixed episode): 7 people, 9.09%
Schizophrenia (a mental disorder characterized by a breakdown of thought processes): 6 people, 7.79%
Mood Swings (an extreme or rapid change in mood): 6 people, 7.79%
Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 6 people, 7.79%

* Approximation only. Some reports may have incomplete information.

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