Buspar and Zomig drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Buspar (buspirone hydrochloride) and Zomig (zolmitriptan). Common drug interactions include limb deformity among females and influenza like illness among males.

The phase IV clinical study analyzes what interactions people have when they take Buspar and Zomig. It is created by eHealthMe based on reports of 47 people who take the same drugs from the FDA, and is updated regularly.

What is Buspar?

Buspar has active ingredients of buspirone hydrochloride. It is often used in stress and anxiety. eHealthMe is studying from 20,463 Buspar users. Check the latest studies of Buspar.

What is Zomig?

Zomig has active ingredients of zolmitriptan. It is often used in migraine. eHealthMe is studying from 7,356 Zomig users. Check the latest studies of Zomig.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.

On Aug, 14, 2026

47 people who take Buspar and Zomig together, and have interactions are studied.

What are the common drug interactions of Buspar and Zomig, by gender? *:

female:

Limb deformity (functional disability of leg)
Medical device pain (pain due to medical device)
Mental impairment (a condition affecting the body, perhaps through sight or hearing loss, a mobility difficulty or a health condition)
Muscle spasticity (tight or stiff muscles and an inability to control those muscles)
Muscular weakness (muscle weakness)
Musculoskeletal discomfort (discomfort in the body's muscles, joints, tendons, ligaments and nerves)
Myalgia (muscle pain)
Myositis (inflammation of the muscles)
Myositis ossificans (a condition that causes abnormal bone formation within deep muscle tissue)
Neurogenic bladder (the normal function of the bladder is to store and empty urine in a coordinated, controlled fashion)

male:

Influenza like illness
Aggression
Insomnia (sleeplessness)
Memory impairment
Muscle spasms (muscle contraction)
Rash
Rectal haemorrhage (bleeding from anus)
Suicidal ideation
Weight increased
Pain

What are the common drug interactions of Buspar and Zomig, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

Aggression
Anger
Constipation
Deafness
Disturbance in attention
Drug ineffective
Erection increased
Fatigue (feeling of tiredness)
Gastric ulcer (stomach ulcer)
Insomnia (sleeplessness)

20-29:

Bipolar disorder (mood disorder)
Dyspnoea (difficult or laboured respiration)
Influenza like illness
Lyme disease (a bacterial infection that is spread to humans by infected ticks)
Multiple sclerosis (a nervous system disease that affects your brain and spinal cord. it damages the myelin sheath)
Obesity (having too much body fat)
Pain
Pyrexia (fever)
Urinary incontinence (inability to control the flow of urine and involuntary urination)
Hypothyroidism (abnormally low activity of the thyroid gland, resulting in retardation of growth and mental development)

30-39:

Headache (pain in head)
Diabetes mellitus (diabetes, caused by a deficiency of the pancreatic hormone insulin)
Diabetes mellitus inadequate control
Diabetic neuropathy (neuropathic disorders that are associated with diabetes mellitus)
Glucose tolerance impaired (blood glucose is raised beyond normal levels, but not high enough to warrant a diabetes diagnosis)
Hyperglycaemia (high blood sugar)
Impaired gastric emptying
Metabolic syndrome (a combination of the medical disorders that, when occurring together, increase the risk of developing cardiovascular disease)
Type 2 diabetes mellitus
Body height decreased

40-49:

Arthralgia (joint pain)
Drug hypersensitivity
Intracranial aneurysm (bulging, weak area in the wall of a cranial artery)
Mood altered (changes in mood)
Nausea (feeling of having an urge to vomit)
Personality change

50-59:

Abdominal distension
Attention-seeking behaviour
Borderline personality disorder
Cardiac valve disease (heart valve disease)
Cellulitis (infection under the skin)
Cystitis (inflammation of the wall of the bladder)
Decreased appetite
Dental caries
Diarrhoea
Dizziness

60+:

Body height decreased
Breast cancer
Headache (pain in head)
Mental impairment (a condition affecting the body, perhaps through sight or hearing loss, a mobility difficulty or a health condition)
Chronic obstructive pulmonary disease (a progressive disease that makes it hard to breathe)
Dyspnoea (difficult or laboured respiration)
Hyperlipidaemia (presence of excess lipids in the blood)
Hypersensitivity
Hypertension (high blood pressure)
Influenza like illness

What are the existing conditions these people have? *

Pain: 12 people, 25.53%
Headache (pain in head): 10 people, 21.28%
Hypothyroidism (abnormally low activity of the thyroid gland, resulting in retardation of growth and mental development): 8 people, 17.02%
Depression: 8 people, 17.02%
Fibromyalgia (a long-term condition which causes pain all over the body): 7 people, 14.89%
High Blood Pressure: 7 people, 14.89%
Hormone Level Abnormal: 5 people, 10.64%
Behcet's Syndrome (involves inflammation of the blood vessels): 5 people, 10.64%
Skin Disorder (skin disease): 5 people, 10.64%
Hypotonia (low muscle tone): 5 people, 10.64%

* Approximation only. Some reports may have incomplete information.

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