Buspirone hcl and Codeine drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Buspirone hcl (buspirone hydrochloride) and Codeine (codeine sulfate). Common drug interactions include intervertebral disc compression among females and chest pain among males.

The phase IV clinical study analyzes what interactions people have when they take Buspirone hcl and Codeine. It is created by eHealthMe based on reports of 22 people who take the same drugs from the FDA, and is updated regularly.

What is Buspirone hcl?

Buspirone hcl has active ingredients of buspirone hydrochloride. It is often used in stress and anxiety. eHealthMe is studying from 9,821 Buspirone hcl users. Check the latest studies of Buspirone hcl.

What is Codeine?

Codeine has active ingredients of codeine sulfate. It is often used in pain. eHealthMe is studying from 42,342 Codeine users. Check the latest studies of Codeine.

On Jul, 14, 2026

22 people who take Buspirone hcl and Codeine together, and have interactions are studied.

Buspirone hcl and Codeine drug interactions.

What are the common drug interactions of Buspirone Hcl and Codeine, by gender? *:

female:

Intervertebral disc compression (spinal disc compression)
Myocardial infarction (destruction of heart tissue resulting from obstruction of the blood supply to the heart muscle)
Nausea (feeling of having an urge to vomit)
Oedema peripheral (superficial swelling)
Pain in extremity
Seasonal allergy (allergic condition due to certain season)
Serum ferritin increased
Tongue dry
Vitamin d decreased
Anaemia (lack of blood)

male:

Chest pain
Bronchitis (inflammation of the mucous membrane in the bronchial tubes)
Head injury
Injury
Nausea (feeling of having an urge to vomit)
Nightmare (unpleasant dream)
Platelet count decreased
Post-traumatic stress disorder
Pruritus (severe itching of the skin)
Road traffic accident

What are the common drug interactions of Buspirone Hcl and Codeine, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

Drug diversion
Drug ineffective
Epistaxis (bleed from the nose)
Hangover
Head injury
Nightmare (unpleasant dream)
Platelet count decreased
Post-traumatic stress disorder
Pruritus (severe itching of the skin)
Road traffic accident

40-49:

Pain in extremity
Paraesthesia (sensation of tingling, tickling, prickling, pricking, or burning of a person's skin with no apparent long-term physical effect)
Peripheral swelling
Pneumonia
Pneumonia mycoplasmal (mycoplasma pneumonia (mp) is a contagious respiratory infection)
Rhinitis (a medical term for irritation and inflammation of the mucous membrane inside the nose)
Sedation
Sexual dysfunction (difficulty experienced by an individual or a couple during any stage of a normal sexual activity)
Social problem
Specific gravity urine increased

50-59:

Glossodynia (a burning or painful sensation in the tongue)
Pain in extremity
Tongue dry
Altered state of consciousness (altered state of mind)
Anaemia (lack of blood)
Aortic dilatation
Arthralgia (joint pain)
Asthenia (weakness)
Atrial fibrillation (fibrillation of the muscles of the atria of the heart)
Balance disorder

60+:

Chest discomfort
Chest pain
Drug hypersensitivity
Gastrooesophageal reflux disease (stomach contents (food or liquid) leak backwards from the stomach into the oesophagus)
Abdominal discomfort
Decreased appetite
Dysgeusia (disorder of the sense of taste)
Nausea (feeling of having an urge to vomit)

What are the existing conditions these people have? *

Narcolepsy (brain's inability to regulate sleep-wake cycles normally): 12 people, 54.55%
Cataplexy (loss of muscle tone accompanied by full conscious awareness): 7 people, 31.82%
Drowsiness: 4 people, 18.18%
Emphysema (chronic respiratory disease - over inflation of the air sacs (alveoli) in the lungs): 2 people, 9.09%

* Approximation only. Some reports may have incomplete information.

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