Bydureon and Zestril drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Bydureon (exenatide synthetic) and Zestril (lisinopril). Common drug interactions include glycosylated haemoglobin increased among females and injection site nodule among males.

The phase IV clinical study analyzes what interactions people have when they take Bydureon and Zestril. It is created by eHealthMe based on reports of 38 people who take the same drugs from the FDA, and is updated regularly.

What is Bydureon?

Bydureon has active ingredients of exenatide synthetic. It is often used in type 2 diabetes. eHealthMe is studying from 24,309 Bydureon users. Check the latest studies of Bydureon.

What is Zestril?

Zestril has active ingredients of lisinopril. It is often used in high blood pressure. eHealthMe is studying from 22,273 Zestril users. Check the latest studies of Zestril.

On Jul, 24, 2026

38 people who take Bydureon and Zestril together, and have interactions are studied.

What are the common drug interactions of Bydureon and Zestril, by gender? *:

female:

Glycosylated haemoglobin increased
Heart rate irregular
Hepatic cirrhosis (chronic liver disease characterized by replacement of liver tissue by fibrosis, scar tissue)
Hepatic neoplasm (liver tumour)
Hepatomegaly (abnormal enlargement of the liver)
Injection site bruising
Injection site erythema (redness at injection site)
Injection site mass
Microalbuminuria (albumin into the urine)
Nasal dryness (dry nose)

male:

Injection site nodule (small swelling or aggregation of cells in the body, esp. an abnormal one at injection site)
Weight decreased
Erythema (redness of the skin)
Genital abscess (build up of pus in genital)
Groin abscess (pus in groin)
Pancreatitis acute (sudden inflammation of pancreas)
Scrotal abscess (pus in scrotum)
Scrotal swelling
Blood glucose decreased
Injection site haemorrhage (bleeding from injection site)

What are the common drug interactions of Bydureon and Zestril, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

n/a

40-49:

Road traffic accident
Weight decreased
Abdominal pain lower
Anxiety
Cellulitis (infection under the skin)
Chronic kidney disease
Erythema (redness of the skin)
Essential hypertension (primary hypertension)
Gastrooesophageal reflux disease (stomach contents (food or liquid) leak backwards from the stomach into the oesophagus)
Groin abscess (pus in groin)

50-59:

Decreased appetite
Weight decreased
Glycosylated haemoglobin decreased
Injection site bruising
Injection site nodule (small swelling or aggregation of cells in the body, esp. an abnormal one at injection site)
Constipation
Heart rate increased
Tinnitus (a ringing in the ears)
Anger
Confusional state

60+:

Nausea (feeling of having an urge to vomit)
Weight decreased
Abdominal discomfort
Fatigue (feeling of tiredness)
Injection site pain
Pain
Renal failure (kidney dysfunction)
Urinary tract disorder
Cataract (clouding of the lens inside the eye)
Constipation

What are the existing conditions these people have? *

High Blood Cholesterol: 14 people, 36.84%
Diabetes: 12 people, 31.58%
Blood Pressure Abnormal: 10 people, 26.32%
Pain: 7 people, 18.42%
Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 6 people, 15.79%
Hypothyroidism (abnormally low activity of the thyroid gland, resulting in retardation of growth and mental development): 5 people, 13.16%
Weight Decreased: 4 people, 10.53%
Constipation: 3 people, 7.89%
Nausea (feeling of having an urge to vomit): 3 people, 7.89%
Hypotension (abnormally low blood pressure): 3 people, 7.89%

* Approximation only. Some reports may have incomplete information.

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