Caffeine and Fluticasone propionate drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Caffeine (caffeine) and Fluticasone propionate (fluticasone propionate). Common drug interactions include bursitis among females and headache among males.

The phase IV clinical study analyzes what interactions people have when they take Caffeine and Fluticasone propionate. It is created by eHealthMe based on reports of 90 people who take the same drugs from the FDA, and is updated regularly.

What is Caffeine?

Caffeine has active ingredients of caffeine. It is often used in fatigue. eHealthMe is studying from 6,667 Caffeine users. Check the latest studies of Caffeine.

What is Fluticasone propionate?

Fluticasone propionate has active ingredients of fluticasone propionate. It is often used in allergies. eHealthMe is studying from 35,174 Fluticasone propionate users. Check the latest studies of Fluticasone propionate.



On Jul, 25, 2026

90 people who take Caffeine and Fluticasone propionate together, and have interactions are studied.

Caffeine and Fluticasone propionate drug interactions.

What are the common drug interactions of Caffeine and Fluticasone Propionate, by gender? *:

female:

  1. Bursitis (inflammation of a bursa, typically one in the knee, elbow, or shoulder)
  2. Enthesopathy (disorder of entheses (bone attachments))
  3. Hyperglycaemia (high blood sugar)
  4. Musculoskeletal stiffness (stiffness of the body's muscles, joints, tendons, ligaments and nerves)
  5. Oral pain
  6. Squamous cell carcinoma (a cancer of a kind of epithelial cell)
  7. Synovial cyst (cyst of joint filled with synovial fluid)
  8. Tardive dyskinesia (a disorder that involves involuntary movements)
  9. Tenosynovitis (inflammation of the fluid-filled sheath (called the synovium) that surrounds a tendon)
  10. Surgery

male:

  1. Headache (pain in head)
  2. Head injury
  3. Road traffic accident
  4. Sleep apnoea syndrome (a sleep-related disorder in which the effort to breathe is diminished or absent)
  5. Spinal disorder (disease of spine a back bone)
  6. Suicidal ideation
  7. Nausea (feeling of having an urge to vomit)
  8. Anxiety
  9. Asthenia (weakness)
  10. Dermatitis (inflammation of the skin resulting from direct irritation by an external agent or an allergic reaction to it)

What are the common drug interactions of Caffeine and Fluticasone Propionate, by age (0-1 to 60+)? *:

0-1:

  1. Dermatitis (inflammation of the skin resulting from direct irritation by an external agent or an allergic reaction to it)
  2. Foetal growth restriction (poor growth of a baby while in the mother's womb during pregnancy)
  3. Hypoxia (low oxygen in tissues)
  4. Jaundice (a yellowish pigmentation of the skin, the conjunctival membranes)
  5. Maternal exposure before pregnancy (use of substance before pregnancy)
  6. Pneumonia aspiration (bronchopneumonia that develops due to the entrance of foreign materials into the bronchial tree)
  7. Respiratory distress (difficulty in breathing)
  8. Bacteraemia (presence of bacteria in the blood)
  9. Chronic respiratory disease
  10. Coagulation factor decreased (less clotting substance in blood)

2-9:

n/a

10-19:

  1. Migraine (headache)

20-29:

  1. Nausea (feeling of having an urge to vomit)
  2. Pleural effusion (water on the lungs)
  3. Pyrexia (fever)
  4. Staphylococcal infection (an infection with staphylococcus bacteria)

30-39:

  1. Hypoxia (low oxygen in tissues)
  2. Injection site erythema (redness at injection site)
  3. Injury
  4. Mental status changes (general changes in brain function, such as confusion, amnesia (memory loss), loss of alertness, loss of orientation)
  5. Muscle spasms (muscle contraction)
  6. Nasal congestion (blockage of the nasal passages usually due to membranes lining the nose becoming swollen from inflamed blood vessels)
  7. Nervousness
  8. Pleural adhesion
  9. Pulmonary oedema (fluid accumulation in the lungs)
  10. Renal impairment (severely reduced kidney function)

40-49:

  1. Hyperglycaemia (high blood sugar)

50-59:

  1. Drug ineffective
  2. Palpitations (feelings or sensations that your heart is pounding or racing)
  3. Stomatitis (inflammation of mucous membrane of mouth)
  4. Rheumatoid arthritis (a chronic progressive disease causing inflammation in the joints)
  5. Alopecia (absence of hair from areas of the body)
  6. Drug intolerance (drug sensitivity)
  7. Head injury
  8. Brain injury
  9. Concussion (short loss of normal brain function in response to a head injury)
  10. Contusion (a type of hematoma of tissue in which capillaries)

60+:

  1. Abdominal discomfort
  2. Cough
  3. Vomiting
  4. Wheezing (a high-pitched whistling sound made while you breath)
  5. Squamous cell carcinoma (a cancer of a kind of epithelial cell)
  6. Insomnia (sleeplessness)
  7. Multiple sclerosis relapse (reoccurrence of a nervous system disease that affects your brain and spinal cord. it damages the myelin sheath)
  8. Facial paralysis (loss of function of face muscle)
  9. Faeces discoloured
  10. Gastric haemorrhage (bleeding stomach)

What are the existing conditions these people have? *

  1. Psoriatic Arthropathy (inflammation of the skin and joints with kin condition which typically causes patches (plaques) of red, scaly skin to develop): 23 people, 25.56%
  2. Asthma: 23 people, 25.56%
  3. Rheumatoid Arthritis (a chronic progressive disease causing inflammation in the joints): 19 people, 21.11%
  4. Narcolepsy (brain's inability to regulate sleep-wake cycles normally): 19 people, 21.11%
  5. Cataplexy (loss of muscle tone accompanied by full conscious awareness): 10 people, 11.11%
  6. Pain: 7 people, 7.78%
  7. Drowsiness: 5 people, 5.56%

* Approximation only. Some reports may have incomplete information.

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Related studies:

Effectiveness of, side effects of, and alternative drugs to the 2 drugs:

Browse all drug interactions of Caffeine and Fluticasone propionate:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Caffeine:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all side effects of Fluticasone propionate:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Caffeine and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Fluticasone propionate and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Related publications that referenced our studies


How the study uses the data?

The study uses data from the FDA. It is based on caffeine and fluticasone propionate (the active ingredients of Caffeine and Fluticasone propionate, respectively), and Caffeine and Fluticasone propionate (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

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