Caffeine and Lithium carbonate drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Caffeine (caffeine) and Lithium carbonate (lithium carbonate). Common drug interactions include arthralgia among females and actinic keratosis among males.

The phase IV clinical study analyzes what interactions people have when they take Caffeine and Lithium carbonate. It is created by eHealthMe based on reports of 28 people who take the same drugs from the FDA, and is updated regularly.

What is Caffeine?

Caffeine has active ingredients of caffeine. It is often used in fatigue. eHealthMe is studying from 6,667 Caffeine users. Check the latest studies of Caffeine.

What is Lithium carbonate?

Lithium carbonate has active ingredients of lithium carbonate. It is often used in bipolar disorder. eHealthMe is studying from 25,651 Lithium carbonate users. Check the latest studies of Lithium carbonate.

On Jul, 20, 2026

28 people who take Caffeine and Lithium carbonate together, and have interactions are studied.

Caffeine and Lithium carbonate drug interactions.

What are the common drug interactions of Caffeine and Lithium Carbonate, by gender? *:

female:

Arthralgia (joint pain)
Surgery
Synovial cyst (cyst of joint filled with synovial fluid)
Tardive dyskinesia (a disorder that involves involuntary movements)
Weight increased
Headache (pain in head)
Intracranial pressure increased (high pressure inside the skull and thus in the brain tissue and cerebrospinal fluid)
Muscle spasms (muscle contraction)
Weight decreased
Arthritis (form of joint disorder that involves inflammation of one or more joints)

male:

Actinic keratosis (skin disease due to sun exposure)
Adenoma benign (non-cancerous tumour -secreting)
Lumbar radiculopathy (radicular pain in the low back and legs)
Melanocytic naevus (a type of lesion that contains nevus cells (a type of melanocyte))
Neuropathy peripheral (surface nerve damage)
Obsessive-compulsive disorder (an anxiety disorder characterized by intrusive thoughts that produce uneasiness, apprehension, fear, or worry;)
Paraesthesia (sensation of tingling, tickling, prickling, pricking, or burning of a person's skin with no apparent long-term physical effect)
Polyp
Rectal haemorrhage (bleeding from anus)
Telangiectasia (small dilated blood vessels near the surface of the skin)

What are the common drug interactions of Caffeine and Lithium Carbonate, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

Drug abuse
Arthralgia (joint pain)
Synovial cyst (cyst of joint filled with synovial fluid)
Tardive dyskinesia (a disorder that involves involuntary movements)
Weight increased
Overdose
Weight decreased
Akathisia (a movement disorder characterized by a feeling of inner restlessness)
Anticholinergic syndrome (absolute or relative reduction in cholinergic activity in the central nervous system)
Back pain

40-49:

Cardiogenic shock (inadequate circulation of blood)
Convulsion (muscles contract and relax rapidly and repeatedly, resulting in an uncontrolled shaking of the body)
Haemodynamic instability (disturbances in the blood movement in our body)
Ileus (a painful obstruction of the ileum or other part of the intestine)
Sinus tachycardia (a heart rhythm with elevated rate of impulses originating from the sinoatrial node)
Transaminases increased
Ventricular arrhythmia (problem with the rate or rhythm of the heartbeat)
Ventricular tachycardia (rapid heartbeat that originates in one of the lower chambers (the ventricles) of the heart)

50-59:

Drug level decreased

60+:

Abdominal discomfort
Drug withdrawal syndrome (interfere with normal social, occupational, or other functioning. are not due to another medical condition, drug use, or discontinuation)
Weight decreased
Feeding disorder (when children refuse to eat certain food groups)
Hypertension (high blood pressure)
Insomnia (sleeplessness)
Loss of consciousness
Malaise (a feeling of general discomfort or uneasiness)
Parkinson's disease
Parkinsonism (degenerative disorder of the central nervous system characterized by tremor and impaired muscular coordination)

What are the existing conditions these people have? *

Narcolepsy (brain's inability to regulate sleep-wake cycles normally): 19 people, 67.86%
Drowsiness: 4 people, 14.29%
Stress And Anxiety: 3 people, 10.71%
Pain: 3 people, 10.71%
Major Depression (a mood state that goes well beyond temporarily feeling sad or blue. it is a serious medical illness that affects one's thoughts, feelings): 3 people, 10.71%
Cataplexy (loss of muscle tone accompanied by full conscious awareness): 3 people, 10.71%
Affective Disorder (mental disorder): 3 people, 10.71%
Drug Dependence: 2 people, 7.14%

* Approximation only. Some reports may have incomplete information.

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