Calcitriol and Sinemet drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Calcitriol (calcitriol) and Sinemet (carbidopa; levodopa). Common drug interactions include renal failure among females and fall among males.

The phase IV clinical study analyzes what interactions people have when they take Calcitriol and Sinemet. It is created by eHealthMe based on reports of 58 people who take the same drugs from the FDA, and is updated regularly.

What is Calcitriol?

Calcitriol has active ingredients of calcitriol. It is often used in hypoparathyroidism. eHealthMe is studying from 24,162 Calcitriol users. Check the latest studies of Calcitriol.

What is Sinemet?

Sinemet has active ingredients of carbidopa; levodopa. It is often used in parkinson's disease. eHealthMe is studying from 29,601 Sinemet users. Check the latest studies of Sinemet.



On Jul, 08, 2026

58 people who take Calcitriol and Sinemet together, and have interactions are studied.

Calcitriol and Sinemet drug interactions.

What are the common drug interactions of Calcitriol and Sinemet, by gender? *:

female:

  1. Renal failure (kidney dysfunction)
  2. Scar
  3. Skin burning sensation
  4. Skin discolouration (change of skin colour)
  5. Skin fibrosis (fibrous tissue formation on skin)
  6. Skin hypertrophy (skin cells enlarges)
  7. Skin induration (an abnormally hard spot or area on the skin)
  8. Skin plaque (red, scaly patches to appear on the skin)
  9. Small intestinal obstruction (blockage in small intestine)
  10. Spondylitis (an inflammation of the vertebra with spinal cord involvement)

male:

  1. Fall
  2. Hallucination (an experience involving the perception of something not present)
  3. Pneumonia aspiration (bronchopneumonia that develops due to the entrance of foreign materials into the bronchial tree)
  4. Confusional state
  5. Dizziness
  6. Nonspecific reaction (unspecified reaction)
  7. Pain in extremity
  8. Peripheral swelling
  9. Acute respiratory failure
  10. Atelectasis (partial or complete collapse of the lung)

What are the common drug interactions of Calcitriol and Sinemet, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

n/a

40-49:

  1. Wrist fracture

50-59:

  1. Tubulointerstitial nephritis (a form of nephritis affecting the interstitium of the kidneys surrounding the tubules)
  2. Chronic kidney disease
  3. Nephrogenic anaemia (anaemia due to kidney disease)
  4. Nephrogenic systemic fibrosis (involves fibrosis of skin, joints, eyes due to kidney disease)
  5. Renal failure (kidney dysfunction)
  6. Renal impairment (severely reduced kidney function)

60+:

  1. Fall
  2. Cellulitis (infection under the skin)
  3. Dyspnoea (difficult or laboured respiration)
  4. Somnolence (a state of near-sleep, a strong desire for sleep)
  5. Angina unstable (chest pain due to ischemia of the heart muscle- unstable)
  6. Areflexia (absence of a reflex)
  7. Arthralgia (joint pain)
  8. Back pain
  9. Balance disorder
  10. Chest pain

What are the existing conditions these people have? *

  1. Pain: 12 people, 20.69%
  2. Constipation: 7 people, 12.07%
  3. Stress And Anxiety: 6 people, 10.34%
  4. Delusion (a false belief or opinion): 6 people, 10.34%
  5. Hallucinations (sensations that appear real but are created by your mind): 6 people, 10.34%
  6. Insomnia (sleeplessness): 6 people, 10.34%
  7. Restless Leg Syndrome (a powerful urge to move your legs): 6 people, 10.34%
  8. High Blood Pressure: 5 people, 8.62%
  9. Gout (uric acid crystals building up in the body): 5 people, 8.62%
  10. Cellulitis (infection under the skin): 4 people, 6.90%

* Approximation only. Some reports may have incomplete information.

Do you take Calcitriol and Sinemet?

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Related studies:

Effectiveness of, side effects of, and alternative drugs to the 2 drugs:

Browse all drug interactions of Calcitriol and Sinemet:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Calcitriol:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all side effects of Sinemet:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Calcitriol and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Sinemet and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

How the study uses the data?

The study uses data from the FDA. It is based on calcitriol and carbidopa; levodopa (the active ingredients of Calcitriol and Sinemet, respectively), and Calcitriol and Sinemet (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

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