Calcium ascorbate and Zestril drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Calcium ascorbate (vitamin c (ascorbic acid)) and Zestril (lisinopril). Common drug interactions include deep vein thrombosis postoperative among females.

The phase IV clinical study analyzes what interactions people have when they take Calcium ascorbate and Zestril. It is created by eHealthMe based on reports of 55 people who take the same drugs from the FDA, and is updated regularly.

What is Calcium ascorbate?

Calcium ascorbate has active ingredients of vitamin c (ascorbic acid). eHealthMe is studying from 1,018 Calcium ascorbate users. Check the latest studies of Calcium ascorbate.

What is Zestril?

Zestril has active ingredients of lisinopril. It is often used in high blood pressure. eHealthMe is studying from 22,273 Zestril users. Check the latest studies of Zestril.



On Jul, 09, 2026

55 people who take Calcium ascorbate and Zestril together, and have interactions are studied.

Calcium ascorbate and Zestril drug interactions.

What are the common drug interactions of Calcium Ascorbate and Zestril, by gender? *:

female:

  1. Deep vein thrombosis postoperative (blood clot in a major vein that usually develops in the legs and/or pelvis after operation)
  2. Dry mouth
  3. Grip strength decreased
  4. Bursitis (inflammation of a bursa, typically one in the knee, elbow, or shoulder)
  5. Drug hypersensitivity
  6. Drug ineffective
  7. Duodenal ulcer perforation (untreated ulcer can burn through the wall of the stomach)
  8. Fibromyalgia (a long-term condition which causes pain all over the body)
  9. Amnesia (deficit in memory caused by brain damage, disease, or psychological trauma)
  10. Asthenia (weakness)

male:

n/a

What are the common drug interactions of Calcium Ascorbate and Zestril, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

n/a

40-49:

  1. Deep vein thrombosis postoperative (blood clot in a major vein that usually develops in the legs and/or pelvis after operation)
  2. Grip strength decreased
  3. Bursitis (inflammation of a bursa, typically one in the knee, elbow, or shoulder)
  4. Decreased appetite
  5. Drug hypersensitivity
  6. Duodenal ulcer perforation (untreated ulcer can burn through the wall of the stomach)
  7. Amnesia (deficit in memory caused by brain damage, disease, or psychological trauma)
  8. Asthenia (weakness)
  9. Confusional state
  10. Depression

50-59:

n/a

60+:

  1. Troponin increased

What are the existing conditions these people have? *

  1. Rheumatoid Arthritis (a chronic progressive disease causing inflammation in the joints): 53 people, 96.36%
  2. Psoriatic Arthropathy (inflammation of the skin and joints with kin condition which typically causes patches (plaques) of red, scaly skin to develop): 48 people, 87.27%
  3. Stress And Anxiety: 19 people, 34.55%
  4. Arthritis (form of joint disorder that involves inflammation of one or more joints): 17 people, 30.91%
  5. Indigestion: 12 people, 21.82%
  6. Fibromyalgia (a long-term condition which causes pain all over the body): 10 people, 18.18%
  7. Crohn's Disease (a condition that causes inflammation of the gastrointestinal tract): 9 people, 16.36%
  8. Psoriasis (immune-mediated disease that affects the skin): 8 people, 14.55%
  9. Systemic Lupus Erythematosus (an autoimmune disease, which means the body's immune system mistakenly, attacks healthy tissue): 7 people, 12.73%
  10. Headache (pain in head): 7 people, 12.73%

* Approximation only. Some reports may have incomplete information.

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Related studies:

Effectiveness of, side effects of, and alternative drugs to the 2 drugs:

Browse all drug interactions of Calcium ascorbate and Zestril:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Calcium ascorbate:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all side effects of Zestril:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Calcium ascorbate and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Zestril and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Related publications that referenced our studies


How the study uses the data?

The study uses data from the FDA. It is based on vitamin c (ascorbic acid) and lisinopril (the active ingredients of Calcium ascorbate and Zestril, respectively), and Calcium ascorbate and Zestril (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

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