Canasa and Doxycycline drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Canasa (mesalamine) and Doxycycline (doxycycline hyclate). Common drug interactions include blood glucose increased among females and anhedonia among males.

The phase IV clinical study analyzes what interactions people have when they take Canasa and Doxycycline. It is created by eHealthMe based on reports of 25 people who take the same drugs from the FDA, and is updated regularly.

What is Canasa?

Canasa has active ingredients of mesalamine. It is often used in ulcerative colitis. eHealthMe is studying from 1,676 Canasa users. Check the latest studies of Canasa.

What is Doxycycline?

Doxycycline has active ingredients of doxycycline hyclate. It is often used in acne. eHealthMe is studying from 60,868 Doxycycline users. Check the latest studies of Doxycycline.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.

On Aug, 20, 2026

25 people who take Canasa and Doxycycline together, and have interactions are studied.

Canasa and Doxycycline drug interactions.

What are the common drug interactions of Canasa and Doxycycline, by gender? *:

female:

Blood glucose increased
Carcinoembryonic antigen increased
Cardioactive drug level below therapeutic
Cardiomegaly (increased size of heart than normal)
Cellulitis (infection under the skin)
Cerebral haemorrhage (bleeding within the brain)
Chest pain
Chills (felling of cold)
Colonic polyp (extra part of colon tissue grow in intestine)
Nausea (feeling of having an urge to vomit)

male:

Anhedonia (inability to experience pleasure from activities usually found enjoyable)
Anxiety
Quality of life decreased
Tibia fracture (fracture of lower leg bone)
Wrist fracture
Osteopenia (a condition where bone mineral density is lower than normal)
Radius fracture
Renal cyst (kidney cyst)
Ulna fracture (fracture inside bone)
Vitamin d deficiency

What are the common drug interactions of Canasa and Doxycycline, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

Headache (pain in head)
Rhinorrhoea (watery mucus discharge from the nose)
Throat irritation

40-49:

Biliary dyskinesia (motility disorder that affects the gallbladder and sphincter of oddi)
Intracranial venous sinus thrombosis (presence of thrombosis (a blood clot) in the dural venous sinuses, which drain blood from the brain)
Sinusitis (inflammation of sinus)
Weight increased
Alanine aminotransferase increased
Aspartate aminotransferase increased
Breast cyst
Headache (pain in head)
Jugular vein thrombosis (clot in jugular vein)
Nausea (feeling of having an urge to vomit)

50-59:

Injury
International normalised ratio increased
Lipomatous hypertrophy of the interatrial septum (non cancer fatty tissue growth within the heart partition)
Localised infection (infection at the single location)
Muscular weakness (muscle weakness)
Nausea (feeling of having an urge to vomit)
Neoplasm (tumour)
Nodal rhythm (40-50 beats per minute)
Obstruction
Pain

60+:

Anxiety
Fall
Back pain
Bronchitis (inflammation of the mucous membrane in the bronchial tubes)
Cardiac failure congestive
Chronic obstructive pulmonary disease (a progressive disease that makes it hard to breathe)
Depression
Haemorrhoids (a swollen vein or group of veins in the region of the anus)
Hallucination (an experience involving the perception of something not present)
Injury

What are the existing conditions these people have? *

Birth Control: 7 people, 28.00%
Pain: 4 people, 16.00%
Hiv Infection: 4 people, 16.00%
High Blood Cholesterol: 4 people, 16.00%
Depression: 4 people, 16.00%
Stress And Anxiety: 3 people, 12.00%
Osteoporosis (bones weak and more likely to break): 3 people, 12.00%
Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 3 people, 12.00%
Fungal Infection: 3 people, 12.00%
Bacterial Infection: 3 people, 12.00%

* Approximation only. Some reports may have incomplete information.

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