Canasa and Spiriva drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Canasa (mesalamine) and Spiriva (tiotropium bromide monohydrate). Common drug interactions include headache among females and diarrhoea among males.

The phase IV clinical study analyzes what interactions people have when they take Canasa and Spiriva. It is created by eHealthMe based on reports of 39 people who take the same drugs from the FDA, and is updated regularly.

What is Canasa?

Canasa has active ingredients of mesalamine. It is often used in ulcerative colitis. eHealthMe is studying from 1,676 Canasa users. Check the latest studies of Canasa.

What is Spiriva?

Spiriva has active ingredients of tiotropium bromide monohydrate. It is often used in chronic obstructive pulmonary disease. eHealthMe is studying from 156,666 Spiriva users. Check the latest studies of Spiriva.

On Jul, 04, 2026

39 people who take Canasa and Spiriva together, and have interactions are studied.

What are the common drug interactions of Canasa and Spiriva, by gender? *:

female:

Headache (pain in head)
Fatigue (feeling of tiredness)
Cardiac failure congestive
Diarrhoea
Gastrooesophageal reflux disease (stomach contents (food or liquid) leak backwards from the stomach into the oesophagus)
Nightmare (unpleasant dream)
Vascular occlusion (sudden blockage of a blood vessel, usually with a clot)
Somnambulism (sleep walking)
Pneumonia
Drug hypersensitivity

male:

Diarrhoea
Weight decreased
Tubulointerstitial nephritis (a form of nephritis affecting the interstitium of the kidneys surrounding the tubules)
Fall
Movement disorder (neurological syndromes where they may be excess of movement or a paucity of movement that is not connected to weakness)
Chronic kidney disease
Dizziness
Presyncope
Psoriasis (immune-mediated disease that affects the skin)
Renal failure (kidney dysfunction)

What are the common drug interactions of Canasa and Spiriva, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

n/a

40-49:

Back pain
Headache (pain in head)
Impaired work ability
Surgery

50-59:

Headache (pain in head)
Fatigue (feeling of tiredness)
Diarrhoea
Weight decreased
Fall
Back pain
Movement disorder (neurological syndromes where they may be excess of movement or a paucity of movement that is not connected to weakness)
Abnormal dreams
Dizziness
Impaired work ability

60+:

Acute respiratory failure
Hypoxia (low oxygen in tissues)
Somnambulism (sleep walking)
Vascular occlusion (sudden blockage of a blood vessel, usually with a clot)
Abdominal pain
Abdominal rigidity
Blood pressure systolic increased
Cataplexy (loss of muscle tone accompanied by full conscious awareness)
Chronic kidney disease
Deep vein thrombosis (blood clot in a major vein that usually develops in the legs and/or pelvis)

What are the existing conditions these people have? *

Narcolepsy (brain's inability to regulate sleep-wake cycles normally): 21 people, 53.85%
Cataplexy (loss of muscle tone accompanied by full conscious awareness): 20 people, 51.28%
High Blood Pressure: 6 people, 15.38%
High Blood Cholesterol: 4 people, 10.26%
Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 4 people, 10.26%
Asthma: 4 people, 10.26%
Hypokalemia (low potassium): 3 people, 7.69%
Osteopenia (a condition where bone mineral density is lower than normal): 3 people, 7.69%
Psoriasis (immune-mediated disease that affects the skin): 3 people, 7.69%
Hiv Infection: 2 people, 5.13%

* Approximation only. Some reports may have incomplete information.

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