Cannabis and Ketoconazole drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Cannabis (marijuana) and Ketoconazole (ketoconazole). Common drug interactions include rash among females and anhedonia among males.

The phase IV clinical study analyzes what interactions people have when they take Cannabis and Ketoconazole. It is created by eHealthMe based on reports of 17 people who take the same drugs from the FDA, and is updated regularly.

What is Cannabis?

Cannabis has active ingredients of marijuana. It is often used in stress and anxiety. eHealthMe is studying from 13,371 Cannabis users. Check the latest studies of Cannabis.

What is Ketoconazole?

Ketoconazole has active ingredients of ketoconazole. It is often used in fungal infection. eHealthMe is studying from 16,014 Ketoconazole users. Check the latest studies of Ketoconazole.

On Jul, 14, 2026

17 people who take Cannabis and Ketoconazole together, and have interactions are studied.

Cannabis and Ketoconazole drug interactions.

What are the common drug interactions of Cannabis and Ketoconazole, by gender? *:

female:

Rash
Abdominal neoplasm (cancer of the stomach)
Arthralgia (joint pain)
Blood corticotrophin increased
Blood glucose decreased
Blood pressure decreased
Blood pressure increased
Chest pain
Communication disorder (speech and language disorder)
Decreased appetite

male:

Anhedonia (inability to experience pleasure from activities usually found enjoyable)
Dysstasia (difficulty in standing)
Carotid artery disease
Chest pain
Chronic kidney disease
Enuresis (repeated inability to control urination)
Erectile dysfunction
Gait disturbance
Haematochezia (passage of stools containing blood)
Hepatic steatosis (fatty liver disease)

What are the common drug interactions of Cannabis and Ketoconazole, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

Decreased appetite
Dermatitis contact (skin reaction (dermatitis) resulting from exposure to allergens)
Drug hypersensitivity
Musculoskeletal discomfort (discomfort in the body's muscles, joints, tendons, ligaments and nerves)
Nausea (feeling of having an urge to vomit)
Skin irritation
Weight fluctuation

40-49:

Attention deficit hyperactivity disorder (a chronic condition including attention difficulty, hyperactivity, and impulsiveness)
Blood cholesterol increased
Blood creatine phosphokinase increased
Chest pain
Enuresis (repeated inability to control urination)
Haematochezia (passage of stools containing blood)
Hepatic steatosis (fatty liver disease)
Hypersomnia (excessive daytime sleepiness (eds))
Hypotension (abnormally low blood pressure)
Infection

50-59:

Bone density decreased
Carotid artery disease
Chest pain
Chronic kidney disease
Communication disorder (speech and language disorder)
Constipation
Decreased appetite
Dehydration (dryness resulting from the removal of water)
Dyspnoea (difficult or laboured respiration)
Dysstasia (difficulty in standing)

60+:

Diarrhoea
Cerebral infarction (less blood supply to brain resulting tissue damage)

What are the existing conditions these people have? *

Hiv Infection: 4 people, 23.53%
Cataplexy (loss of muscle tone accompanied by full conscious awareness): 3 people, 17.65%
Narcolepsy (brain's inability to regulate sleep-wake cycles normally): 3 people, 17.65%
Drowsiness: 3 people, 17.65%
Metastatic Malignant Melanoma (spreadable cancer tumour of melanine): 2 people, 11.76%
High Blood Pressure: 2 people, 11.76%
Blood Pressure Abnormal: 2 people, 11.76%
Body Tinea (ringworm of the body): 2 people, 11.76%
Oral Candidiasis (fungal infection of mouth): 2 people, 11.76%
Brain Oedema (excess accumulation of fluid in the intracellular or extracellular spaces of the brain): 1 person, 5.88%

* Approximation only. Some reports may have incomplete information.

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