Cannabis and Vimpat drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Cannabis (marijuana) and Vimpat (lacosamide). Common drug interactions include pain in extremity among females and acute psychosis among males.

The phase IV clinical study analyzes what interactions people have when they take Cannabis and Vimpat. It is created by eHealthMe based on reports of 40 people who take the same drugs from the FDA, and is updated regularly.

What is Cannabis?

Cannabis has active ingredients of marijuana. It is often used in stress and anxiety. eHealthMe is studying from 13,371 Cannabis users. Check the latest studies of Cannabis.

What is Vimpat?

Vimpat has active ingredients of lacosamide. It is often used in epilepsy. eHealthMe is studying from 20,832 Vimpat users. Check the latest studies of Vimpat.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.

On Sep, 03, 2026

40 people who take Cannabis and Vimpat together, and have interactions are studied.

What are the common drug interactions of Cannabis and Vimpat, by gender? *:

female:

Pain in extremity
Dyspnoea (difficult or laboured respiration)
Skin discolouration (change of skin colour)
Drug ineffective
Balance disorder
Anger
Contusion (a type of hematoma of tissue in which capillaries)
Eyelid injury
Fall
Formication (a sensation that exactly resembles that of small insects crawling on (or under) the skin)

male:

Acute psychosis (period of mentally unstable behaviour)
Status epilepticus (a life-threatening condition in which the brain is in a state of persistent seizure)
Cognitive disorder (mental health disorders affects learning, memory, perception, and problem solving)
Depression
Dizziness
Dysarthria (speech disorder)
Gait disturbance
Hyponatraemia (abnormally low level of sodium in the blood; associated with dehydration)
Movement disorder (neurological syndromes where they may be excess of movement or a paucity of movement that is not connected to weakness)
Multiple system atrophy (degeneration of nerve cells in specific areas of the brain)

What are the common drug interactions of Cannabis and Vimpat, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

Partial seizures (seizures which affect only a part of the brain at onset)

20-29:

Adverse drug reaction
Amnesia (deficit in memory caused by brain damage, disease, or psychological trauma)
Balance disorder
Chest discomfort
Diplopia (double vision)
Dry mouth
Overdose
Syncope (loss of consciousness with an inability to maintain postural tone)
Tremor (trembling or shaking movements in one or more parts of your body)

30-39:

Acute psychosis (period of mentally unstable behaviour)
Affective disorder (mental disorder)
Amnesia (deficit in memory caused by brain damage, disease, or psychological trauma)
Asthenia (weakness)
Ataxia (loss of full control of bodily movements)
Balance disorder
Cerebellar atrophy (degeneration of the section of the brain responsible for balance, voluntary muscle movements)
Cognitive disorder (mental health disorders affects learning, memory, perception, and problem solving)
Depression
Dizziness

40-49:

Dyspnoea (difficult or laboured respiration)
Pain in extremity
Skin discolouration (change of skin colour)
Altered state of consciousness (altered state of mind)
Drug abuse
Miosis (constriction of the pupil of the eye, resulting from a normal response to an increase in light)

50-59:

Anger
Balance disorder
Paranoia (psychotic disorder characterized by delusions of persecution with or without grandeur)
Abdominal pain upper
Constipation
Laceration (tearing of soft body tissue)
Agitation (state of anxiety or nervous excitement)
Bundle branch block right (absence of transmission of electric impulses from the atrioventricular (av) bundle of his to the right ventricle)
Cardiogenic shock (inadequate circulation of blood)
Consciousness fluctuating

60+:

n/a

What are the existing conditions these people have? *

Seizures (abnormal excessive or synchronous neuronal activity in the brain): 16 people, 40.00%
Partial Seizures (seizures which affect only a part of the brain at onset): 6 people, 15.00%
High Blood Cholesterol: 4 people, 10.00%
Fever: 4 people, 10.00%
Blood Pressure Abnormal: 4 people, 10.00%
Dyskinesia (abnormality or impairment of voluntary movement): 2 people, 5.00%
Complex Partial Seizures (epileptic seizure): 2 people, 5.00%

* Approximation only. Some reports may have incomplete information.

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