Capoten and Glipizide drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Capoten (captopril) and Glipizide (glipizide). Common drug interactions include cellulitis among females and cardiac arrest among males.

The phase IV clinical study analyzes what interactions people have when they take Capoten and Glipizide. It is created by eHealthMe based on reports of 44 people who take the same drugs from the FDA, and is updated regularly.

What is Capoten?

Capoten has active ingredients of captopril. It is often used in high blood pressure. eHealthMe is studying from 2,954 Capoten users. Check the latest studies of Capoten.

What is Glipizide?

Glipizide has active ingredients of glipizide. It is often used in diabetes. eHealthMe is studying from 64,852 Glipizide users. Check the latest studies of Glipizide.



On Jul, 18, 2026

44 people who take Capoten and Glipizide together, and have interactions are studied.

Capoten and Glipizide drug interactions.

What are the common drug interactions of Capoten and Glipizide, by gender? *:

female:

  1. Cellulitis (infection under the skin)
  2. Coronary artery disease (plaque building up along the inner walls of the arteries of the heart, which narrows the arteries and restricts blood flow to the heart)
  3. Decreased appetite
  4. Dehydration (dryness resulting from the removal of water)
  5. Depression
  6. Diabetes mellitus inadequate control
  7. Diastolic dysfunction
  8. Dyspepsia (indigestion)
  9. Erythema (redness of the skin)
  10. Flank pain (a distressing sensation experienced around the lower back and the upper abdomen)

male:

  1. Cardiac arrest
  2. Oedema peripheral (superficial swelling)
  3. Lethargy (tiredness)
  4. Pancytopenia (medical condition in which there is a reduction in the number of red and white blood cells, as well as platelets)
  5. Pleural effusion (water on the lungs)
  6. Renal injury (kidney injury)
  7. Respiratory distress (difficulty in breathing)
  8. Staphylococcal infection (an infection with staphylococcus bacteria)
  9. Weakness
  10. Abdominal pain upper

What are the common drug interactions of Capoten and Glipizide, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

n/a

40-49:

  1. Myocardial infarction (destruction of heart tissue resulting from obstruction of the blood supply to the heart muscle)
  2. Anxiety
  3. Back pain
  4. Dyspnoea (difficult or laboured respiration)
  5. Fatigue (feeling of tiredness)
  6. Musculoskeletal chest pain (pain in chest muscle or nerve or bones)
  7. Nausea (feeling of having an urge to vomit)
  8. Pruritus (severe itching of the skin)
  9. Weight decreased
  10. Weight increased

50-59:

  1. Acidosis (build-up of carbon dioxide in the blood)
  2. Adverse drug reaction
  3. Agitation (state of anxiety or nervous excitement)
  4. Anaemia (lack of blood)
  5. Arthralgia (joint pain)
  6. Atrioventricular block first degree (heart block first degree)
  7. Bacteraemia (presence of bacteria in the blood)
  8. Bladder prolapse (bulging of one or more of the pelvic organs into the vagina)
  9. Blood glucose increased
  10. Blood urea increased

60+:

  1. Cardiac arrest
  2. Crepitations (noises are produced by the rubbing of parts one against the other)
  3. Pancytopenia (medical condition in which there is a reduction in the number of red and white blood cells, as well as platelets)
  4. Pleural effusion (water on the lungs)
  5. Pulmonary congestion (congestion in the lungs)
  6. Respiratory distress (difficulty in breathing)
  7. Staphylococcal infection (an infection with staphylococcus bacteria)
  8. Weakness
  9. Abdominal pain upper
  10. Anorexia (eating disorder characterized by immoderate food restriction and irrational fear of gaining weight)

What are the existing conditions these people have? *

  1. High Blood Cholesterol: 5 people, 11.36%
  2. Insulin-Requiring Type Ii Diabetes Mellitus: 4 people, 9.09%
  3. Stroke (sudden death of a portion of the brain cells due to a lack of oxygen): 3 people, 6.82%
  4. Psoriasis (immune-mediated disease that affects the skin): 3 people, 6.82%
  5. Pain In Extremity: 3 people, 6.82%
  6. Pain: 3 people, 6.82%
  7. Multiple Sclerosis (a nervous system disease that affects your brain and spinal cord. it damages the myelin sheath): 3 people, 6.82%

* Approximation only. Some reports may have incomplete information.

Do you take Capoten and Glipizide?

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Related studies:

Effectiveness of, side effects of, and alternative drugs to the 2 drugs:

Browse all drug interactions of Capoten and Glipizide:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Capoten:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all side effects of Glipizide:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Capoten and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Glipizide and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Related publications that referenced our studies


How the study uses the data?

The study uses data from the FDA. It is based on captopril and glipizide (the active ingredients of Capoten and Glipizide, respectively), and Capoten and Glipizide (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.



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