Captopril and Artane drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Captopril (captopril) and Artane (trihexyphenidyl hydrochloride). Common drug interactions include extrapyramidal disorder among females and normochromic normocytic anaemia among males.

The phase IV clinical study analyzes what interactions people have when they take Captopril and Artane. It is created by eHealthMe based on reports of 11 people who take the same drugs from the FDA, and is updated regularly.

What is Captopril?

Captopril has active ingredients of captopril. It is often used in high blood pressure. eHealthMe is studying from 17,438 Captopril users. Check the latest studies of Captopril.

What is Artane?

Artane has active ingredients of trihexyphenidyl hydrochloride. It is often used in parkinson's disease. eHealthMe is studying from 3,619 Artane users. Check the latest studies of Artane.

On Jul, 25, 2026

11 people who take Captopril and Artane together, and have interactions are studied.

What are the common drug interactions of Captopril and Artane, by gender? *:

female:

Extrapyramidal disorder (involuntary muscle spasms in the face and neck)
Fall
Hypertrophy (increase in the volume of an organ or tissue due to the enlargement of its component cells)
Intraventricular haemorrhage (intraventricular bleeding)
Neuroleptic malignant syndrome (a life-threatening neurological disorder most often caused by an adverse reaction to neuroleptic or antipsychotic agents)
Orthostatic hypotension (a medical condition consisting of a sudden decrease in blood pressure when a person stands up)
Pancreatitis (inflammation of pancreas)
Pancreatitis acute (sudden inflammation of pancreas)
Pancreatitis chronic (chronic inflammation of pancreas)
Pleural effusion (water on the lungs)

male:

Normochromic normocytic anaemia (forms of anaemia in which the average size and haemoglobin content of the red blood cells are within normal limits)
Constipation
Abdominal distension
Abdominal pain upper
Abdominal tenderness
Abscess (pus)
Acute prerenal failure (prerenal acute renal failure (arf) occurs when a sudden reduction in blood flow to the kidney)
Anxiety
Asthenia (weakness)
Atrial fibrillation (fibrillation of the muscles of the atria of the heart)

What are the common drug interactions of Captopril and Artane, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

n/a

40-49:

Cholecystitis acute (rapid infection of gallbladder)
Diabetic retinopathy (damage to the retina caused by complications of diabetes)
Electrocardiogram qt corrected interval prolonged
Electrocardiogram qt prolonged
Neuroleptic malignant syndrome (a life-threatening neurological disorder most often caused by an adverse reaction to neuroleptic or antipsychotic agents)
Pancreatitis (inflammation of pancreas)
Pancreatitis acute (sudden inflammation of pancreas)
Pancreatitis chronic (chronic inflammation of pancreas)
Type 2 diabetes mellitus
Vision blurred

50-59:

n/a

60+:

Disorientation (disability in which the senses of time, direction, and recognition of people and places)
Fall
Blood urea increased
Cerebral haematoma (collection of blood in brain)
Chest pain
Constipation
Depression
Dizziness
Erythroblastosis (he abnormal presence of erythroblasts in the blood)
Escherichia infection (bacterial infection by escherichia coli)

What are the existing conditions these people have? *

Schizophrenia (a mental disorder characterized by a breakdown of thought processes): 2 people, 18.18%
Depression: 2 people, 18.18%
Stress And Anxiety: 1 person, 9.09%
Sleep Disorder: 1 person, 9.09%
Schizophrenia, Undifferentiated Type (a type characterized by the presence of prominent psychotic symptoms but not classifiable as catatonic, disorganized, or paranoid): 1 person, 9.09%
Impaired Gastric Emptying: 1 person, 9.09%
Cardiac Disorder: 1 person, 9.09%

* Approximation only. Some reports may have incomplete information.

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