Captopril and Doxycycline drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Captopril (captopril) and Doxycycline (doxycycline hyclate). Common drug interactions include atrial fibrillation among females and chronic kidney disease among males.

The phase IV clinical study analyzes what interactions people have when they take Captopril and Doxycycline. It is created by eHealthMe based on reports of 63 people who take the same drugs from the FDA, and is updated regularly.

What is Captopril?

Captopril has active ingredients of captopril. It is often used in high blood pressure. eHealthMe is studying from 17,438 Captopril users. Check the latest studies of Captopril.

What is Doxycycline?

Doxycycline has active ingredients of doxycycline hyclate. It is often used in acne. eHealthMe is studying from 60,866 Doxycycline users. Check the latest studies of Doxycycline.

On Jul, 23, 2026

63 people who take Captopril and Doxycycline together, and have interactions are studied.

Captopril and Doxycycline drug interactions.

What are the common drug interactions of Captopril and Doxycycline, by gender? *:

female:

Atrial fibrillation (fibrillation of the muscles of the atria of the heart)
Cardiogenic shock (inadequate circulation of blood)
Depressed level of consciousness
Haemorrhagic diathesis (bleeding tendency)
Hypoxia (low oxygen in tissues)
Intestinal ischaemia (decreased supply of oxygenated blood to the intestines)
Liver disorder (liver diseases)
Multi-organ failure (multisystem organ failure)
Respiratory failure (inadequate gas exchange by the respiratory system)
Arthritis (form of joint disorder that involves inflammation of one or more joints)

male:

Chronic kidney disease
Dyspnoea (difficult or laboured respiration)
Ventricular extrasystoles (premature cardiac contraction)
Anxiety
Arthralgia (joint pain)
Asthenia (weakness)
Bronchitis (inflammation of the mucous membrane in the bronchial tubes)
Cardiac failure congestive
Cardioactive drug level increased
Cerebrovascular accident (sudden death of some brain cells due to lack of oxygen when the blood flow to the brain is impaired by blockage or rupture)

What are the common drug interactions of Captopril and Doxycycline, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

n/a

40-49:

Chronic kidney disease
Arrhythmia (irregular heartbeat)
Depressed level of consciousness
Osteonecrosis (death of bone)
Nephrosclerosis (hardening of the kidney due to renovascular disease)
Cardiac arrest
Chest pain
Coma (state of unconsciousness lasting more than six hours)
Cyanosis (lack of oxygen in body leads to blue appearance of skin ,mucous membrane nails)
Fall

50-59:

Multi-organ failure (multisystem organ failure)
Respiratory failure (inadequate gas exchange by the respiratory system)
Arteriosclerosis (thickening and hardening of arteries)
Arthritis (form of joint disorder that involves inflammation of one or more joints)
Cardiac failure congestive
Crohn's disease (a condition that causes inflammation of the gastrointestinal tract)
Dyspnoea (difficult or laboured respiration)
Inflammatory bowel disease
Irritable bowel syndrome
Large intestine perforation (hole in large intestine)

60+:

Chronic kidney disease
Renal failure (kidney dysfunction)
Blood urea increased
Bone pain
Cellulitis (infection under the skin)
Coronary artery occlusion (complete obstruction of blood flow in a coronary artery)
Diabetes mellitus (diabetes, caused by a deficiency of the pancreatic hormone insulin)
Dysuria (painful or difficult urination)
Fatigue (feeling of tiredness)
Food craving

What are the existing conditions these people have? *

Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 11 people, 17.46%
Pain: 8 people, 12.70%
High Blood Cholesterol: 5 people, 7.94%
Infection: 4 people, 6.35%
Hepatic Neoplasm Malignant (liver cancer): 4 people, 6.35%

* Approximation only. Some reports may have incomplete information.

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