Carafate and Codeine drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Carafate (sucralfate) and Codeine (codeine sulfate). Common drug interactions include arteriosclerosis among females and asthenia among males.

The phase IV clinical study analyzes what interactions people have when they take Carafate and Codeine. It is created by eHealthMe based on reports of 80 people who take the same drugs from the FDA, and is updated regularly.

What is Carafate?

Carafate has active ingredients of sucralfate. It is often used in gastroesophageal reflux disease. eHealthMe is studying from 14,028 Carafate users. Check the latest studies of Carafate.

What is Codeine?

Codeine has active ingredients of codeine sulfate. It is often used in pain. eHealthMe is studying from 42,342 Codeine users. Check the latest studies of Codeine.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.

On Aug, 16, 2026

80 people who take Carafate and Codeine together, and have interactions are studied.

What are the common drug interactions of Carafate and Codeine, by gender? *:

female:

Arteriosclerosis (thickening and hardening of arteries)
Constipation
Neuropathy peripheral (surface nerve damage)
Oral candidiasis (fungal infection of mouth)
Pneumonia
Pulmonary fibrosis (formation or development of excess fibrous connective tissue (fibrosis) in the lungs)
Autoimmune lymphoproliferative syndrome (lymph proliferative disorder)
Calculus ureteric (stone in ureter)
Contusion (a type of hematoma of tissue in which capillaries)
Haematuria (presence of blood in urine)

male:

Asthenia (weakness)
Drug ineffective
Cellulitis (infection under the skin)
Chronic kidney disease
Drug hypersensitivity
Fatigue (feeling of tiredness)
General symptom
Hyperparathyroidism secondary (an abnormally high concentration of parathyroid hormone in the blood, resulting in weakening of the bones through loss of calcium-secondary)
Hypotension (abnormally low blood pressure)
Malaise (a feeling of general discomfort or uneasiness)

What are the common drug interactions of Carafate and Codeine, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

Drug ineffective
Haematochezia (passage of stools containing blood)
Pruritus (severe itching of the skin)
Vomiting

20-29:

Diarrhoea
Abdominal pain
Abdominal pain upper
Biliary dyskinesia (motility disorder that affects the gallbladder and sphincter of oddi)
Contusion (a type of hematoma of tissue in which capillaries)
Depression
Dyspepsia (indigestion)
Eye swelling
Furuncle (infection of the hair follicle)
Hypertension (high blood pressure)

30-39:

n/a

40-49:

Oesophagitis (inflammation of oesophagus)
Oropharyngeal pain
Osteoarthritis (a joint disease caused by cartilage loss in a joint)
Osteonecrosis of jaw (death of bone of jaw)
Osteopenia (a condition where bone mineral density is lower than normal)
Physical disability
Pollakiuria (abnormally frequent passage of relatively small quantities or urine)
Retching (strong involuntary effort to vomit)
Rib fracture
Scoliosis (a medical condition in which a person's spine is curved from side to side)

50-59:

Chronic kidney disease
Drug hypersensitivity
Nephrogenic anaemia (anaemia due to kidney disease)
Renal failure (kidney dysfunction)
Nausea (feeling of having an urge to vomit)
Abdominal pain
Choking (mechanical obstruction of the flow of air from the environment into the lungs)
Cholecystitis (infection of gallbladder)
Constipation
Death

60+:

Drug hypersensitivity
Chronic kidney disease
Asthenia (weakness)
Body height decreased
Bronchitis (inflammation of the mucous membrane in the bronchial tubes)
Cataract (clouding of the lens inside the eye)
Chronic obstructive pulmonary disease (a progressive disease that makes it hard to breathe)
Cystoid macular oedema (fluid accumulation after cataract surgery)
Drug effect decreased
Drug ineffective

What are the existing conditions these people have? *

Depression: 10 people, 12.50%
Bone Loss: 10 people, 12.50%
High Blood Pressure: 6 people, 7.50%
Immune System Disorder: 5 people, 6.25%
Headache (pain in head): 4 people, 5.00%
Diarrhea: 4 people, 5.00%
Asthma: 4 people, 5.00%

* Approximation only. Some reports may have incomplete information.

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