Carbidopa and Zonisamide drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Carbidopa (carbidopa) and Zonisamide (zonisamide). Common drug interactions include drug ineffective among females and contusion among males.

The phase IV clinical study analyzes what interactions people have when they take Carbidopa and Zonisamide. It is created by eHealthMe based on reports of 11 people who take the same drugs from the FDA, and is updated regularly.

What is Carbidopa?

Carbidopa has active ingredients of carbidopa. It is often used in parkinson's disease. eHealthMe is studying from 3,061 Carbidopa users. Check the latest studies of Carbidopa.

What is Zonisamide?

Zonisamide has active ingredients of zonisamide. It is often used in epilepsy. eHealthMe is studying from 11,445 Zonisamide users. Check the latest studies of Zonisamide.

On Aug, 12, 2026

11 people who take Carbidopa and Zonisamide together, and have interactions are studied.

Carbidopa and Zonisamide drug interactions.

What are the common drug interactions of Carbidopa and Zonisamide, by gender? *:

female:

Drug ineffective
Therapeutic response unexpected
Chronic kidney disease
Confusional state
Disease progression
Epistaxis (bleed from the nose)
Gastrointestinal haemorrhage (bleeding gastrointestinal tract)
Gout (uric acid crystals building up in the body)
Hyperparathyroidism secondary (an abnormally high concentration of parathyroid hormone in the blood, resulting in weakening of the bones through loss of calcium-secondary)
Memory impairment

male:

Contusion (a type of hematoma of tissue in which capillaries)
Dyskinesia (abnormality or impairment of voluntary movement)
Road traffic accident
Cognitive disorder (mental health disorders affects learning, memory, perception, and problem solving)
Freezing phenomenon
Hypokinesia (decreased bodily movement)
Muscle rigidity (muscle stiffness)
Nausea (feeling of having an urge to vomit)
On and off phenomenon
Somnolence (a state of near-sleep, a strong desire for sleep)

What are the common drug interactions of Carbidopa and Zonisamide, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

n/a

40-49:

Gastrointestinal haemorrhage (bleeding gastrointestinal tract)

50-59:

n/a

60+:

Contusion (a type of hematoma of tissue in which capillaries)
Dyskinesia (abnormality or impairment of voluntary movement)
Chronic kidney disease
Confusional state
Disease progression
Epistaxis (bleed from the nose)
Gout (uric acid crystals building up in the body)
Hyperparathyroidism secondary (an abnormally high concentration of parathyroid hormone in the blood, resulting in weakening of the bones through loss of calcium-secondary)
Memory impairment
Nephrogenic anaemia (anaemia due to kidney disease)

What are the existing conditions these people have? *

Pulmonary Embolism (blockage of the main artery of the lung): 1 person, 9.09%
Nerve Injury: 1 person, 9.09%
Menopause (end of monthly cycles in women): 1 person, 9.09%
Meningioma Benign (non cancer tumour of membranes that cover the brain and spinal cord just inside the skull): 1 person, 9.09%
Liver Disorder (liver diseases): 1 person, 9.09%
Insomnia (sleeplessness): 1 person, 9.09%
Idiopathic Generalised Epilepsy (epileptic disorders that are believed to have a strong underlying genetic basis): 1 person, 9.09%
High Blood Pressure: 1 person, 9.09%
Gout (uric acid crystals building up in the body): 1 person, 9.09%
Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 1 person, 9.09%

* Approximation only. Some reports may have incomplete information.

Do you take Carbidopa and Zonisamide?

- Personalize this study to your gender, age, symptoms and drugs
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously