Cardizem cd and Aredia drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Cardizem cd (diltiazem hydrochloride) and Aredia (pamidronate disodium). Common drug interactions include bone disorder among females and pain among males.

The phase IV clinical study analyzes what interactions people have when they take Cardizem cd and Aredia. It is created by eHealthMe based on reports of 54 people who take the same drugs from the FDA, and is updated regularly.

What is Cardizem cd?

Cardizem cd has active ingredients of diltiazem hydrochloride. It is often used in high blood pressure. eHealthMe is studying from 6,045 Cardizem cd users. Check the latest studies of Cardizem cd.

What is Aredia?

Aredia has active ingredients of pamidronate disodium. It is often used in breast cancer. eHealthMe is studying from 15,364 Aredia users. Check the latest studies of Aredia.



On Jul, 13, 2026

54 people who take Cardizem cd and Aredia together, and have interactions are studied.

Cardizem cd and Aredia drug interactions.

What are the common drug interactions of Cardizem Cd and Aredia, by gender? *:

female:

  1. Bone disorder
  2. Bone marrow oedema (inflammation that causes much than the needed fluid in a bone)
  3. Bradycardia (abnormally slow heart action)
  4. Calculus urinary (stone in urinary system)
  5. Cardiac failure congestive
  6. Cellulitis (infection under the skin)
  7. Cerebrovascular accident (sudden death of some brain cells due to lack of oxygen when the blood flow to the brain is impaired by blockage or rupture)
  8. Confusional state
  9. Cough
  10. Decreased interest

male:

  1. Pain
  2. Bone disorder
  3. Osteonecrosis of jaw (death of bone of jaw)
  4. Blood calcium decreased
  5. Chest pain
  6. Oedema peripheral (superficial swelling)
  7. Depression
  8. Confusional state
  9. Impaired healing
  10. Asthenia (weakness)

What are the common drug interactions of Cardizem Cd and Aredia, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

  1. Abdominal distension
  2. Abdominal pain
  3. Abnormal behaviour
  4. Amnesia (deficit in memory caused by brain damage, disease, or psychological trauma)
  5. Anaemia (lack of blood)
  6. Anogenital warts
  7. Arteriosclerosis coronary artery (thickening and hardening of arteries- coronary artery)
  8. Asthenia (weakness)
  9. Asthma
  10. Atelectasis (partial or complete collapse of the lung)

10-19:

n/a

20-29:

n/a

30-39:

n/a

40-49:

  1. Depression
  2. Rheumatoid arthritis (a chronic progressive disease causing inflammation in the joints)
  3. Anaemia (lack of blood)
  4. Anogenital warts
  5. Asthenia (weakness)
  6. Back injury
  7. Back pain
  8. Bone disorder
  9. Bone neoplasm malignant (cancer of bone)
  10. Bone pain

50-59:

  1. Impaired healing
  2. Intervertebral disc degeneration (spinal disc degeneration)
  3. Osteoarthritis (a joint disease caused by cartilage loss in a joint)
  4. Pain
  5. Rash
  6. Skin ulcer
  7. Staphylococcal infection (an infection with staphylococcus bacteria)
  8. Anaemia (lack of blood)
  9. Arthritis (form of joint disorder that involves inflammation of one or more joints)
  10. Asthenia (weakness)

60+:

  1. Pain
  2. Anxiety
  3. Mitral valve incompetence (inefficient heart valve)
  4. Osteonecrosis of jaw (death of bone of jaw)
  5. Pulmonary hypertension (increase in blood pressure in the lung artery)
  6. Tricuspid valve incompetence (inefficient heart valve)
  7. Cardiac failure congestive
  8. Dyspnoea (difficult or laboured respiration)
  9. International normalised ratio increased
  10. Renal failure (kidney dysfunction)

What are the existing conditions these people have? *

  1. Osteoporosis (bones weak and more likely to break): 19 people, 35.19%
  2. Multiple Myeloma (cancer of the plasma cells): 15 people, 27.78%
  3. Metastases To Bone (cancer spreads to bone): 10 people, 18.52%
  4. Inflammation: 5 people, 9.26%
  5. Nausea (feeling of having an urge to vomit): 3 people, 5.56%
  6. Depression: 3 people, 5.56%
  7. Breast Cancer Metastatic: 3 people, 5.56%

* Approximation only. Some reports may have incomplete information.

Do you take Cardizem cd and Aredia?

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Related studies:

Effectiveness of, side effects of, and alternative drugs to the 2 drugs:

Browse all drug interactions of Cardizem cd and Aredia:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Cardizem cd:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all side effects of Aredia:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Cardizem cd and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Aredia and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

How the study uses the data?

The study uses data from the FDA. It is based on diltiazem hydrochloride and pamidronate disodium (the active ingredients of Cardizem cd and Aredia, respectively), and Cardizem cd and Aredia (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

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